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View Full Version : What can pass through the skin transdermally?


Wishbone Ash
09-25-2005, 01:20 AM
Isn't this based on the size of the molecules? IE certain molecules are too big to pass through?

Also what about rubbing alcohol, can it be absorbed into the skin?

KarlGauss
09-25-2005, 01:29 AM
You may find this interesting (http://www.sciencedirect.com/science?_ob=ArticleURL&_udi=B6T6C-4FSK7TF-3&_coverDate=07%2F31%2F2005&_alid=316460917&_rdoc=1&_fmt=&_orig=search&_qd=1&_cdi=5027&_sort=d&view=c&_acct=C000050221&_version=1&_urlVersion=0&_userid=10&md5=da07fd1399bb12ff55d8fc7f28b07b77) - I really don't know enough about this subject to be helpful.

Searching for 'iontophoresis' is likely to aid your web (and other) searches immensely.

astro
09-25-2005, 01:37 AM
Hydroflouric acid (http://www.bu.edu/es/labsafety/ESMSDSs/MSHydFluoricAcid.html)

CynicalGabe
09-25-2005, 01:46 AM
Many chemical warfare agents are dermally active, especially nerve and blister agents.

Huerta88
09-25-2005, 01:54 AM
Dimethyl sulfoxide (DMSO) gained some notoriety (and advocacy) over the past couple of decades, based in part on its ability to operate transdermally. Fans said this allowed it to be super therapeutic for everything from soup to nuts, critics said it could kill you. Web search on DMSO will turn up scads of stuff.

We're all, of course, ignoring the obvious, indeed, canonical, transdermal agent: herbal penis enlargement patches.

Der Trihs
09-25-2005, 03:15 AM
Some mercury compounds can pass through the skin. I remember a news story a few years ago; a scientist working with the stuff got a drop on her skin and died.

Mr2001
09-25-2005, 03:25 AM
Nicotine, estrogen, and progesterone all come in patch form.

Bryan Ekers
09-25-2005, 03:41 AM
I know chocolate's fattening effect can be transmitted through the eyes....

Ruken
09-25-2005, 11:20 AM
Some mercury compounds can pass through the skin. I remember a news story a few years ago; a scientist working with the stuff got a drop on her skin and died.Worse, Karen Wetterhahn died after the dimethyl mercury went through her glove ( :eek: ) and through her skin.
linky (http://www.dartmouth.edu/~toxmetal/HMKW.shtml)
I work with some nasty stuff in lab, and it's hard to remember that those gloves don't really do much at all for some chemicals.

Erinaceus europaeus
09-25-2005, 11:36 AM
LSD can pass through the skin.

Ragiel
09-25-2005, 11:39 AM
Nicotine, estrogen, and progesterone all come in patch form.

Testosterone, scopolamine, Fentanyl ...

Smeghead
09-25-2005, 12:55 PM
What can pass through the skin transdermally?

Everything. There is no other way to pass through the skin.

Stark Raven Mad
09-25-2005, 01:02 PM
DMSO is used extensively in bodybuilding circles to facilitate the absorption of various steroids.