View Single Post
  #43  
Old 06-26-2017, 06:40 PM
Qadgop the Mercotan Qadgop the Mercotan is offline
Charter Member
 
Join Date: Apr 2000
Location: Slithering on the hull
Posts: 25,755
Quote:
Originally Posted by Quartz View Post
Here's how to do it.
Acetylizing is not always easy, and it can go awry. Could end up with cholesterol instead. Hence the rhymes, sung to the tune of "Jingle Bells". We used to sing this in organic chemistry lab in the mid 70's, when the mood was Christmassy.

Take an acetate,
Condense it with a mate
Pretty soon you have
Acetoacetate.
Let 'em have a ball
You get geraniol,
Add another isoprene
And you've got farnesol.

Farnesol, farnesol, good old farnesol,
First it goes to squalene, then you get cholesterol.
Farnesol, farnesol, good old farnesol,
First it goes to squalene, then you get cholesterol.

Now squalene makes a roll,
Becomes lanosterol
The extra methyls do
Come off as CO2;
Then comes zymosterol,
And then desmosterol
If you don't take Triparanol
You get cholesterol.

Repeat chorus