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Old 02-03-2013, 07:28 AM
Mr. Kobayashi is offline
Join Date: Feb 2004
Posts: 4,712
In Max Brook's seminal zombie survival guide he says that immediate amputation of a bitten extremity has (IIRC) a 10% chance of success.

In the Walking Dead universe it's pretty effective in the TV series;
Hershel is bitten in the ankle and has his leg immediately amputated by Rick with an axe...which he has been using as an weapon against zombies. Hmmm. Anyway, he passes out but survives.

In the Walking Dead video game you can choose to
cut off your forearm after being bitten in the wrist. However some time has lapsed between the bite and amputation, so it doesn't work. The main difference though is that you don't black out as much if you amputate the arm. You also encounter a zombie with one arm so you're not the only one to try it and fail.