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Old 03-02-2005, 09:31 AM
Loopydude Loopydude is offline
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Join Date: Dec 2003
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I'd say if you're positive for antibodies for two kinds of antigen from the same virus, the chance that it is a false positive is so remote as to be not worth considering. If I might hazard a guess, you're probably a chronic carrier with too few circulating viral particles to be detectable in the bank's immunoassay. A test for circulating HBV DNA will clinch it, and it might not be a bad idea to get one.

As pointed out above, low titer is not no titer, and no titer is the only kind that can't lead to infection of a recipient. It's perfectly reasonable, given your serology, to conclude that your blood does pose an unacceptable risk. Even in the absense of a positive result in a sensitive PCR-based assay, it would still be inappropriate to give your blood to another person. You've clearly been exposed to competant virus in amounts sufficient to elicit the sort of immune response characteristic of infection. Once you've been infected, that's it; no more blood doning. It's simply too dangerous for the folks downstream. Certainly, the lower the viral load, the lower the chance of infection, but nobody wants to play Russian roulette.