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Old 02-02-2013, 11:38 PM
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Der Trihs is offline
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Join Date: Aug 2005
Location: California
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It depends on the nature of the fictional pathogen. Something that's carried by blood would be everywhere in seconds, so amputation is useless. Something that travels up the nerves to the brain on the other hand could potentially be stopped by amputation; I recall reading that rabies can be theoretically* stopped that way, if it's a limb that is bitten.

*The problem being that we have better methods these days, and even if we didn't, unless you know the person is infected you'd risk cutting off a limb for nothing.