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  #1  
Old 06-14-2005, 07:35 AM
Chairman Pow Chairman Pow is offline
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Dissolving pills under tongue

I've noticed that some medicatins ask that you dissolve the pills under your tongue before swallowing. Why is this?

I imagine that it has something to do with making sure that the pill is fully dissolved before it enters your stomach and is thus absorbed faster (and letting the enzymes in the mouth work on it as well). Or perhaps the membrane under the tongue is thin enough to absorb stuff directly?
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  #2  
Old 06-14-2005, 08:05 AM
Pjen Pjen is online now
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Quote:
Originally Posted by Chairman Pow
Or perhaps the membrane under the tongue is thin enough to absorb stuff directly?
Correct- sub lingual adminstration is quicker than gastric and as quick as suppository. In both sub-lingual and rectal form the medicine passes through thin skin directly into inerstitial fluid surrounding venul;es and arterioles and hence straight into the blood supply. Additionally it also bypasses what is called first pass elimination- everything going into the stomach and absorbed into the bloodstream there goes directly to the liver which may work frantically to get the chemical out of the blood stream on its 'first pass' through the liver.

Glyceril Tri-Nitrate is given sublingually- fast adminsitartion and misses first pass, therefore going directly to the heart and having a quick and major effect there.

Note: Chewing tobacco works in the same way!
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  #3  
Old 06-14-2005, 09:32 AM
Ike Witt Ike Witt is offline
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Quote:
Originally Posted by Pjen
Note: Chewing tobacco works in the same way!
Skoal can fight angina?
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Old 06-14-2005, 10:02 AM
Pjen Pjen is online now
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Originally Posted by adam yax
Skoal can fight angina?
ho ho ho
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  #5  
Old 06-14-2005, 01:49 PM
Mathochist Mathochist is offline
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Quote:
Originally Posted by adam yax
Skoal can fight angina?
I've never known someone with an 'gina who liked tobacco chewers.
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  #6  
Old 06-14-2005, 06:34 PM
Chairman Pow Chairman Pow is offline
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This is getting out of hand.

Thanks for the answer though. Suddenly all those bizzare directions to swish stuff in my mouth make sense.

Does this work with anything, or is it only things that are prone to being absorbed? Like, would it work with my liquid vitamins, or alcohol?
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  #7  
Old 06-14-2005, 06:38 PM
Doug Bowe Doug Bowe is offline
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Vitamins?

Well, I've had bariatric surgery and have to take B-12 sub lingual once a week. It's either that or take an hour and a half a month and pay VNA for a b-12 shot.
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  #8  
Old 06-14-2005, 07:24 PM
ouryL ouryL is offline
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no tastebuds under tongue
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  #9  
Old 06-14-2005, 07:39 PM
I can't believe that's butter! I can't believe that's butter! is offline
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Can this be done with something like aspirin in the event of a horrible migraine, and so forth?
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