The Straight Dope

Go Back   Straight Dope Message Board > Main > General Questions

Reply
 
Thread Tools Display Modes
  #1  
Old 06-19-2006, 12:31 PM
neutron star neutron star is offline
Guest
 
Join Date: Feb 2000
English names for the Romanian medications "Distonocalm" and "Diclofenac" ?

I'm watching the Romanian film The Death of Mr. Lazarescu, and I've found it to be rather poorly subtitled. There is some seriously broken English, and several words don't seem to be translated at all. Among them are two medicines that Mr. Lazarescu asks of his neighbors, "Distonocalm," and "Diclofenac."

Google is no help (all I get is Romanian sites; obviously I don't speak the language), and Babelfish doesn't translate from Romanian.
Reply With Quote
Advertisements  
  #2  
Old 06-19-2006, 12:39 PM
Slithy Tove Slithy Tove is offline
Guest
 
Join Date: Jan 2000
Diclofenac is the generic name for Voltaren, and I'm looking forward to finding out what Distonocalm is.
Reply With Quote
  #3  
Old 06-19-2006, 01:02 PM
neutron star neutron star is offline
Guest
 
Join Date: Feb 2000
Whoops. Distonocalm was the only one that I actually searched for. Now that I've Googled Dicolofenac, I see that it's the same generic name in English as it is in Romanian. I assumed both were Romanian names, so I didn't search for the second.

The neighbor in the movie had Diclofenac, but not Disotonocalm, and said that she didn't buy drugs that were that strong. One Romanian Google result mentioned the drug in the same paragraph as diazepam, so I'm thinking that it could be a benzodiazepine.
Reply With Quote
  #4  
Old 06-19-2006, 07:21 PM
Bob Scene Bob Scene is offline
Guest
 
Join Date: Oct 2000
I apologize for Googling up this answer and not knowing what I'm talking about, but I thought this was interesting.

Apparently, Distonocalm is a brand name for a mixture of drugs that isn't commonly sold in English-speaking countries, so there's no English equivalent.

According to this page, Distonocalm consists of atropine, propanolol, amobarbital and ergotamine.

Atropine is a parasympathetic antagonist, propanolol is a sympathetic antagonist (usually used as a blood-pressure medicine), amobarbital is a barbiturate and ergotamine is a vasoconstrictor used for treating migraines.

What does that combination do? My Romanian is a little rusty (I studied Spanish in high school), but I think it's for calming down your digestive tract. It's not a benzodiazepine, but amobarbital works on the same GABA-gated chloride channels that benzodiazepines do, so Distonocalm would probably have some kind of tranquilizing effect.
Reply With Quote
  #5  
Old 06-19-2006, 07:35 PM
Qadgop the Mercotan Qadgop the Mercotan is offline
Charter Member
 
Join Date: Apr 2000
Location: Slithering on the hull
Posts: 22,414
Quote:
Originally Posted by Bob Scene
Distonocalm consists of atropine, propanolol, amobarbital and ergotamine.

Atropine is a parasympathetic antagonist, propanolol is a sympathetic antagonist (usually used as a blood-pressure medicine), amobarbital is a barbiturate and ergotamine is a vasoconstrictor used for treating migraines.

What does that combination do?
It appears to me to be more like someone's shotgun approach to treating migraines. I've seen all 4 classes of meds used to treat migraines before.

Tho GI problems would be my second guess. Except for the ergotamine and propranolol.

At any rate, it seems like a stupid combination to me. Atropine to raise the heart rate, propranolol to lower it? Ergotamine to act as a stimulant, and amobarbital as a sedative? If it's in the right doses, all these meds might cancel each other out!
Reply With Quote
  #6  
Old 06-20-2006, 03:27 AM
Dr_Paprika Dr_Paprika is offline
Guest
 
Join Date: Oct 2000
Indicatii: Distonii neuro-vegetative cu manifestari digestive (dureri abdominale, difuze sau localizate, senzatie de balonare sau greutate epigastrica, arsuri epigastrice, greturi, varsaturi, tulburari ale tranzitului intestinal), cu manifestari cardiovasculare (tahicardie, extrasistole, palpitatii, puls labil, crize de vasoconstrictie sau vasodilatatie cu senzatie de valuri de caldura, transpiratie, ameteli, extremitati reci, parestezii etc.). Tulburari neurovegetative din nevroza astenica, climacteriu, hipertiroidism, hipertensiune arteriala in stadiu incipient.

But of course.
Reply With Quote
  #7  
Old 06-20-2006, 06:31 AM
Bob Scene Bob Scene is offline
Guest
 
Join Date: Oct 2000
Quote:
Originally Posted by Dr_Paprika
It appears to me to be more like someone's shotgun approach to treating migraines. I've seen all 4 classes of meds used to treat migraines before.

Tho GI problems would be my second guess.
No, it's definitely for digestive problems. Dr_Paprika's quote is from the page I linked to, which gives the indications for the drug in Romanian. The quote starts out "Indications: Neuro-vegetative dystonia with digestive manifestations (abdominal pain...)" Like I said, my Romanian is weak, but I can understand that much. ("Neuro-vegetative" apparently refers to the autonomic nervous system in general.) After the list of digestive indications it has a list of cardiovascular indications, so apparently it's for some combination of the two.

It may or may not be a smart combination for that purpose, but that's what it's intended for.
Reply With Quote
  #8  
Old 06-20-2006, 08:21 PM
Qadgop the Mercotan Qadgop the Mercotan is offline
Charter Member
 
Join Date: Apr 2000
Location: Slithering on the hull
Posts: 22,414
Quote:
Originally Posted by Bob Scene
Quote:
Originally Posted by Dr_Paprika
It appears to me to be more like someone's shotgun approach to treating migraines. I've seen all 4 classes of meds used to treat migraines before.

Tho GI problems would be my second guess.
Um, that was my quote, not Doc Pap's. I would hate to have him credited with my wrong answer.

It still seems like a stupid combination of drugs to me.

I knew romanian was derived from latin, but I didn't realize how close it was!
Reply With Quote
  #9  
Old 06-20-2006, 08:28 PM
gabriela gabriela is offline
Guest
 
Join Date: Mar 2006
Propanolol has for years been (mis?)used for a temporary appearance of calm in people who have bad nerves. It ablates the heart's response to adrenalin. So your heart can't race on it, even when you're scared.

Classical musicians are notorious for using it for auditions, when any nerves can cause the fingers to stumble into mistakes. It makes you calm in panicky situations, so calm.

Psycho Chief (if anyone remembers him from the post chain about the poor guy with the Brut bottle up his ass) took propanolol to calm himself when he went to present his little research project in front of the Society of University Surgeons, a notorious group of sharks in the guise of academics. He said someone came up to him afterwards and said, "It would have been nice if you could have sounded as if you were interested at all in your own presentation."

Propanolol. For people who don't even want to sound interested.
Reply With Quote
  #10  
Old 02-03-2013, 02:57 PM
hiltoncoa hiltoncoa is offline
Guest
 
Join Date: Feb 2013
In case anyone still wants to know years later . . .

Hi all, I know that I'm stumbling upon this thread many years after the question was asked, but I thought someone may need to know this information for medical reasons in the future. Distonocalm is a medication used to treat acute headaches and migraines. It is also a psychotropic drug, and caution should be taken to not mix it with alcohol, as it may cause hallucinations. The Romanian government has placed controls on this drug to prevent addicts from abusing it for this reason.

http://www.gov.ro/press-release__l2a39432.html

It is not a medication for treating GI issues, and should not be taken without a prescription.

I hope this helps answer this question.
Reply With Quote
Reply



Bookmarks

Thread Tools
Display Modes

Posting Rules
You may not post new threads
You may not post replies
You may not post attachments
You may not edit your posts

BB code is On
Smilies are On
[IMG] code is Off
HTML code is Off

Forum Jump


All times are GMT -5. The time now is 03:02 PM.


Powered by vBulletin® Version 3.8.7
Copyright ©2000 - 2014, vBulletin Solutions, Inc.

Send questions for Cecil Adams to: cecil@chicagoreader.com

Send comments about this website to: webmaster@straightdope.com

Terms of Use / Privacy Policy

Advertise on the Straight Dope!
(Your direct line to thousands of the smartest, hippest people on the planet, plus a few total dipsticks.)

Publishers - interested in subscribing to the Straight Dope?
Write to: sdsubscriptions@chicagoreader.com.

Copyright 2013 Sun-Times Media, LLC.