How come when you smoke it makes you have to poop??

Well I guess there isn’t much more to this question…I am guessing Tobacco must be a natural laxative???

I smoked for 20 years, and never noticed this effect.

I have.

Translation: There are nicotine receptors in your intestines. When you smoke, the nicotine triggers them, and they trigger your intestines to contract. Everything inside moves down the track a bit and the poop at the end knocks on the exit door. But if you smoke too much, the effect is lost.

The Master has spoken.

And what he says is pretty much what WhyNot said:

John Locke noticed the same thing: