The Straight Dope

Go Back   Straight Dope Message Board > Main > General Questions

Reply
 
Thread Tools Display Modes
  #1  
Old 07-07-2009, 12:56 AM
Hazle Weatherfield Hazle Weatherfield is offline
Guest
 
Join Date: Dec 2006
Diphenhydramine and restless legs

Why does Simply Sleep (diphenhydramine) give me restless legs for about an hour after I take it. NyQuil sometimes does this; not as often, though.
Reply With Quote
Advertisements  
  #2  
Old 07-07-2009, 07:34 AM
Mama Zappa Mama Zappa is offline
Charter Member
 
Join Date: Feb 2003
Posts: 9,874
This stuff (also known as Benadryl) is notorious for aggravating RLS. Any antihistamine can do so, actually, but Benadryl is sort of the poster child for the linkage as it's the active ingredient in over the counter sleep aids (i.e. does exactly the OPPOSITE of what you want it to do).

http://rls.org/Page.aspx?pid=543
Reply With Quote
  #3  
Old 07-07-2009, 10:01 AM
kayaker kayaker is offline
Member
 
Join Date: Jul 2009
Location: Western Pennsylvania
Posts: 15,321
Yep, I hate diphenhydramine. It makes me feel very sleepy, yet I am unable to sleep.
Reply With Quote
  #4  
Old 07-07-2009, 10:17 AM
Harriet the Spry Harriet the Spry is offline
Guest
 
Join Date: Jun 2003
In my personal experience, I can get the benefit I need for allergy control from a children's dose (12.5 mg) of diphenhydramine. That's half of what's in one adult regular pill. It makes me a little drowsy, enough to help me fall asleep, but doesn't give me unpleasant side effects or make me too drowsy to stay awake if I take it during the day. It's possible the standard dose is higher than you need.

Talk to your doctor or pharmacist to discuss the right dosage for you .
Reply With Quote
  #5  
Old 07-08-2009, 06:38 PM
Napier Napier is offline
Charter Member
 
Join Date: Jan 2001
Location: Mid Atlantic, USA
Posts: 7,982
Interesting. For perhaps 10 years now I have noticed a bit of RLS when taking codiene. I wondered if it was perhaps because I was moving my legs less when taking it, so that they actually DID need to move more to have their normal activity level.
Reply With Quote
  #6  
Old 07-08-2009, 08:39 PM
Hazle Weatherfield Hazle Weatherfield is offline
Guest
 
Join Date: Dec 2006
Thanks, everyone! I had no idea!
Reply With Quote
  #7  
Old 07-08-2009, 08:39 PM
Mama Zappa Mama Zappa is offline
Charter Member
 
Join Date: Feb 2003
Posts: 9,874
Quote:
Originally Posted by Napier View Post
Interesting. For perhaps 10 years now I have noticed a bit of RLS when taking codiene. I wondered if it was perhaps because I was moving my legs less when taking it, so that they actually DID need to move more to have their normal activity level.
That would be pretty odd - codeine is an opiate, and those generally HELP restless legs. I once had some cough syrup with codeine and my symptoms were much better; ditto other times since then where I've had Vicodin. Was there anything else in the codeine prep you were taking?

Of course, for every rule, there's an exception!
Reply With Quote
  #8  
Old 07-08-2009, 09:50 PM
RickJay RickJay is offline
Charter Jays Fan
Moderator
 
Join Date: Jun 2000
Location: Oakville, Canada
Posts: 32,069
Quote:
Originally Posted by Mama Zappa View Post
That would be pretty odd - codeine is an opiate, and those generally HELP restless legs.
I have RLS and codeine has no effect on it at all, nor any other opiate. Benadryl definitely makes it worse.

I take clonazepam, which seems to work pretty well and doesn't give me any of the side effects usually attributed to it except possibly morning headaches (though I used to get those anyway.)
Reply With Quote
Reply



Bookmarks

Thread Tools
Display Modes

Posting Rules
You may not post new threads
You may not post replies
You may not post attachments
You may not edit your posts

BB code is On
Smilies are On
[IMG] code is Off
HTML code is Off

Forum Jump


All times are GMT -5. The time now is 04:09 AM.


Powered by vBulletin® Version 3.8.7
Copyright ©2000 - 2014, vBulletin Solutions, Inc.

Send questions for Cecil Adams to: cecil@chicagoreader.com

Send comments about this website to: webmaster@straightdope.com

Terms of Use / Privacy Policy

Advertise on the Straight Dope!
(Your direct line to thousands of the smartest, hippest people on the planet, plus a few total dipsticks.)

Publishers - interested in subscribing to the Straight Dope?
Write to: sdsubscriptions@chicagoreader.com.

Copyright 2013 Sun-Times Media, LLC.