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Old 04-27-2017, 03:56 PM
That Don Guy That Don Guy is offline
Join Date: Feb 2011
Posts: 3,833
Dr. Kudner (Kal Penn's character) on House; Penn had just accepted his job with the Obama administration.

Ed Marinaro's character (whose name escapes me) on Hill Street Blues.

Dr. Armstrong on St. Elsewhere - this may be stretching the definition of "major" somewhat, but the circumstances that led to the character's death were controversial; they wrote the character off of the show because somebody (either the producers or NBC) felt that too many viewers were turned off by the fact that she was Asian.