I’ll note at the start that, as @XT already stated, these experiments were with viruses not related to SARS_CoV-2 so the pandemic could not have arisen from them. These were the experiments I was describing in the Rand Paul thread as a “rescue-of-function” as opposed to “gain-of-function”. No experiments were designed to make more virulent or transmissible viruses. They were simply testing out each bat virus spike proteins by making hybrid viruses. They tested in cell culture and in mice. However, one of the constructs made mice more sick than the original WIV1 virus.
Tabak said in his letter that the research plan had been reviewed by the agency before funding, and the agency determined that it did not meet the NIH’s definition of gain-of-function — or what the agency terms [research involving enhanced pathogens of pandemic potential](Research Involving Enhanced Potential Pandemic Pathogens | National Institutes of Health (NIH)) — “because these bat coronaviruses had not been shown to infect humans.” It therefore was not subject to review under the Department of Health and Human Services’ framework for enhanced pathogens.
But, he added, “out of an abundance of caution and as an additional layer of oversight,” the agency had outlined criteria in the terms and conditions of the grant award for a secondary review, “such as a requirement that the grantee report immediately a one log increase in growth,” meaning a 10-fold increase in viral growth, to “determine whether the research aims should be re-evaluated or new biosafety measures should be enacted.”
“EcoHealth failed to report this finding right away, as was required by the terms of the grant,” the letter reads. “EcoHealth is being notified that they have five days from today to submit to NIH any and all unpublished data from the experiments and work conducted under this award.”
Tabak then spent the bulk of the letter’s second page explaining that bat coronaviruses used in the experiments “could not have been the source of SARS-CoV-2 and the COVID-19 pandemic,” as we’ve established.
The NIH is simply being extra careful, as they should be. Meanwhile Republicans lie about it to suggest that this caused the pandemic because that’s what they do.