# AB+ blood type

**URL:** <https://boards.straightdope.com/t/ab-blood-type/623557>\
**Category:** Factual Questions\
**Created:** [May 30, 2012, 5:03pm UTC](https://boards.straightdope.com/t/ab-blood-type/623557 "2012-05-30T17:03:29Z")\
**Posts on this page:** 14\
**Page:** 3

<div class="post-metadata">

**Author:** ![drewder](https://avatars.discourse-cdn.com/v4/letter/d/57b2e6/32.png) [@drewder](https://boards.straightdope.com/u/drewder)\
**Post date:** [June 1, 2012, 12:10am UTC](https://boards.straightdope.com/t/ab-blood-type/623557/41 "2012-06-01T00:10:16Z")

</div>

> [@kayT](#):
>
> Just a slight hijack: do you all who donate do so at Red Cross? I am O+ and would maybe donate but not to them. I’m sort of curious to know if those of you who had a negative experience (being hounded; being treated like they’re doing you a favor) were at Red Cross.

The best donation experience I’ve had was when I was in the army in Monterey CA. They actually gave me a little shot of lidocaine which made the entire experience completely pain free. I’ve donated with the red cross although not very often and I’ve never had them hound me.

---

<div class="post-metadata">

**Author:** ![Cub\_Mistress](https://avatars.discourse-cdn.com/v4/letter/c/ea666f/32.png) [@Cub\_Mistress](https://boards.straightdope.com/u/Cub_Mistress)\
**Post date:** [June 1, 2012, 1:27am UTC](https://boards.straightdope.com/t/ab-blood-type/623557/42 "2012-06-01T01:27:51Z")

</div>

I’m AB+ and I don’t really care if my RBCs get tossed, my body can make plenty of them! (given a good diet, etc.) I have my 5 gallon pin from the Red Cross and have given blood through Blood Assurance, too ( not too close in time, I promise!) I have seen patients come back from the brink of death with a transfusion and go home an live for many relatively happy years after a tranfusion. I am proud to have been a teeny-tiny part of that.

---

<div class="post-metadata">

**Author:** ![KarlGrenze](https://avatars.discourse-cdn.com/v4/letter/k/dbc845/32.png) [@KarlGrenze](https://boards.straightdope.com/u/KarlGrenze)\
**Post date:** [June 1, 2012, 1:54am UTC](https://boards.straightdope.com/t/ab-blood-type/623557/43 "2012-06-01T01:54:42Z")

</div>

Red blood cells are not the only component of blood, there are also platelets and plasma. Those ABs whose RBC’s may not get as much use as other blood types… Well, ask about plasma or platelet apheresis, where they take the blood, centrifuge it, and only keep the parts they want (plasma and/or platelets). The rest is returned to the donor.

It takes longer, but can be done more frequently.

---

<div class="post-metadata">

**Author:** ![Pai325](https://avatars.discourse-cdn.com/v4/letter/p/c68b51/32.png) [@Pai325](https://boards.straightdope.com/u/Pai325)\
**Post date:** [June 1, 2012, 4:45am UTC](https://boards.straightdope.com/t/ab-blood-type/623557/44 "2012-06-01T04:45:58Z")

</div>

> [@Antigen](#):
>
> Nope nope nope.
> 
> Rh negative folks can get Rh positive blood once, and sometimes more than once, in an emergency. That’s because the antibodies against the Rh (D) aren’t formed until the body’s been exposed to it, as opposed to the Anti-A and Anti-B that are naturally occurring in the body (depending on blood type).(ASCP)

Do they still have the rhogam shot? Do you give that if you have to give positive blood to a negative person?

---

<div class="post-metadata">

**Author:** ![Antigen](https://avatars.discourse-cdn.com/v4/letter/a/848f3c/32.png) [@Antigen](https://boards.straightdope.com/u/Antigen)\
**Post date:** [June 1, 2012, 10:31am UTC](https://boards.straightdope.com/t/ab-blood-type/623557/45 "2012-06-01T10:31:18Z")

</div>

> [@Pai325](#):
>
> Do they still have the rhogam shot? Do you give that if you have to give positive blood to a negative person?

Depends on the circumstances. I’ve personally never seen it happen, but we had a protocol in place to suggest it, when we gave a Rh-pos unit to an Rh-neg woman of childbearing age. That’s because the anti-D she makes in response to a Rh-pos unit may affect any pregnancies she has afterwards. But when we gave 75-year-old men Opos units because we didn’t have enough Oneg to keep them alive, we didn’t bother.

What did happen more regularly is a Rhogam shot given to an Rh negative young woman who received Rh positive platelets. Platelets don’t have the RhD antigen on them, but the process of platelet collection always leaves behind a small amount of red cells. Because platelets are often so hard to come by, due to their short shelf life (5 days) we gave positive units to negative patients much more often than with units of red cells.

---

<div class="post-metadata">

**Author:** ![KarlGrenze](https://avatars.discourse-cdn.com/v4/letter/k/dbc845/32.png) [@KarlGrenze](https://boards.straightdope.com/u/KarlGrenze)\
**Post date:** [June 1, 2012, 1:59pm UTC](https://boards.straightdope.com/t/ab-blood-type/623557/46 "2012-06-01T13:59:51Z")

</div>

> [@Antigen](#):
>
> What did happen more regularly is a Rhogam shot given to an Rh negative young woman who received Rh positive platelets. Platelets don’t have the RhD antigen on them, but the process of platelet collection always leaves behind a small amount of red cells. Because platelets are often so hard to come by, due to their short shelf life (5 days) we gave positive units to negative patients much more often than with units of red cells.

Ah, makes sense that they want my platelets much more than my whole blood (A-). Well, that and the fact that I have lots of platelets, apparently.

---

<div class="post-metadata">

**Author:** ![bup](https://avatars.discourse-cdn.com/v4/letter/b/6bbea6/32.png) [@bup](https://boards.straightdope.com/u/bup)\
**Post date:** [June 1, 2012, 2:31pm UTC](https://boards.straightdope.com/t/ab-blood-type/623557/47 "2012-06-01T14:31:39Z")

</div>

> [@kayT](#):
>
> Just a slight hijack: do you all who donate do so at Red Cross? I am O+ and would maybe donate but not to them. I’m sort of curious to know if those of you who had a negative experience (being hounded; being treated like they’re doing you a favor) were at Red Cross.

I donate to LifeSource; however, LifeSource and the Red Cross have set things up like a cartel, since they aren’t really ‘in competition’ - they’ve divided up things, pretty much. Here in Chicagoland, LifeSource is more-or-less the only choice. Some places, the Red Cross may be the only choice.

Google your location and blood donations.

---

<div class="post-metadata">

**Author:** ![CC](https://avatars.discourse-cdn.com/v4/letter/c/f1d935/32.png) [@CC](https://boards.straightdope.com/u/CC)\
**Post date:** [June 1, 2012, 6:14pm UTC](https://boards.straightdope.com/t/ab-blood-type/623557/48 "2012-06-01T18:14:11Z")

</div>

1. the underlying issue of the OP is certainly one of the most intriguing questions to show up here.

2. Years ago, I was fired from donating blood when they discovered that I had antibodies for Hep B in my blood. They said that I must have come in contact with it at some point. I don’t have antigens. I have no evidence of the virus. But they wouldn’t take my blood. Has anything changed? Can I go back to donating?

---

<div class="post-metadata">

**Author:** ![artemis](https://avatars.discourse-cdn.com/v4/letter/a/91b2a8/32.png) [@artemis](https://boards.straightdope.com/u/artemis)\
**Post date:** [June 1, 2012, 6:47pm UTC](https://boards.straightdope.com/t/ab-blood-type/623557/49 "2012-06-01T18:47:37Z")

</div>

> [@mnemosyne](#):
>
> You make me doubt myself. I was - until this post - rather thoroughly convinced that the blood could be filtered or centrifuged (I don’t know the technique) to selectively remove the Rh+ while leaving behind usable blood products for donation to Rh- patients. Is that not correct?

No, it’s not correct. The Rh factors (which are actually a whole complex of antigens; the one you’re referring to is technically known as D) are membrane-bound proteins, and are an integral part of the red cell. You can’t remove them.

---

<div class="post-metadata">

**Author:** ![artemis](https://avatars.discourse-cdn.com/v4/letter/a/91b2a8/32.png) [@artemis](https://boards.straightdope.com/u/artemis)\
**Post date:** [June 1, 2012, 6:55pm UTC](https://boards.straightdope.com/t/ab-blood-type/623557/50 "2012-06-01T18:55:29Z")

</div>

> [@Nunavut\_Boy](#):
>
> You should reconsider. Even if they do throw out some of the AB cells donated, AB plasma is like liquid gold. Whenever there’s a big emergency and they don’t have time to type the patient, they give O neg cells and AB plasma. And since in a massive bleed situation, cells and plasma and platelets are given in a 1:1:1 ratio, we need a lot of it!

Precisely! There’s no such thing as a single “universal blood donor,” despite the fact that people bring it up in these sorts of threads all the time. Type O red cells can be given to anyone (with rare exceptions), but type O plasma can ONLY be given to people with type O blood. The opposite is true for type AB: AB red cells can only be give to AB recipients, but type AB plasma can be given to anyone (again, with rare exceptions).

Doesn’t matter what blood type you have: if you can donate, do so. SOME part of what comes out of your veins will be useful!

---

<div class="post-metadata">

**Author:** ![artemis](https://avatars.discourse-cdn.com/v4/letter/a/91b2a8/32.png) [@artemis](https://boards.straightdope.com/u/artemis)\
**Post date:** [June 1, 2012, 7:03pm UTC](https://boards.straightdope.com/t/ab-blood-type/623557/51 "2012-06-01T19:03:56Z")

</div>

> [@CC](#):
>
> Years ago, I was fired from donating blood when they discovered that I had antibodies for Hep B in my blood. They said that I must have come in contact with it at some point. I don’t have antigens. I have no evidence of the virus. But they wouldn’t take my blood. Has anything changed? Can I go back to donating?

I don’t think anything has changed (at least not as far as I could fine with a quick Google search). As of right now, you’re still permanently deferred. It doesn’t hurt to keep checking every few years, though, just in case the policy is revised some day.

---

<div class="post-metadata">

**Author:** ![Hari\_Seldon](https://sea3.discourse-cdn.com/straightdope/user_avatar/boards.straightdope.com/hari_seldon/32/5173_2.png) [@Hari\_Seldon](https://boards.straightdope.com/u/Hari_Seldon)\
**Post date:** [June 2, 2012, 12:19am UTC](https://boards.straightdope.com/t/ab-blood-type/623557/52 "2012-06-02T00:19:27Z")

</div>

> [@KarlGauss](#):
>
> You are essentially describing the [Bombay Blood Group](http://en.wikipedia.org/wiki/Bombay_blood) phenomemon (as noted by Mr. **Smeghead** above).
> 
> As an aside, I strongly suspect that a typo is more common, much more, than the Bombay Blood Group (1:250000).

That was a fascinating quote, but I bet that that isn’t the only way it can happen. Genetics is more complicated than most of us are aware of. Incidentally, it suggests it could happen with AB as well as just A. I still bet on mistyping–or the milkman.

---

<div class="post-metadata">

**Author:** ![Diceman](https://avatars.discourse-cdn.com/v4/letter/d/22d042/32.png) [@Diceman](https://boards.straightdope.com/u/Diceman)\
**Post date:** [June 2, 2012, 2:53am UTC](https://boards.straightdope.com/t/ab-blood-type/623557/53 "2012-06-02T02:53:17Z")

</div>

> [@Hari\_Seldon](#):
>
> That was a fascinating quote, but I bet that that isn’t the only way it can happen. Genetics is more complicated than most of us are aware of. Incidentally, it suggests it could happen with AB as well as just A. I still bet on mistyping–or the milkman.

Again, the milkman isn’t a possibility. An AB person _must_ have one A parent and one B parent. If the mother is O, then it isn’t possible that the AB son is biologically hers, regardless of who the father is. Ditto for the father: he can’t be the biological father. If everyone’s blood type was recorded correctly, then pretty much the only possibility is that the AB son was adopted.

---

<div class="post-metadata">

**Author:** ![md2000](https://avatars.discourse-cdn.com/v4/letter/m/73ab20/32.png) [@md2000](https://boards.straightdope.com/u/md2000)\
**Post date:** [June 2, 2012, 4:22am UTC](https://boards.straightdope.com/t/ab-blood-type/623557/54 "2012-06-02T04:22:29Z")

</div>

> [@Diceman](#):
>
> Again, the milkman isn’t a possibility. An AB person _must_ have one A parent and one B parent. If the mother is O, then it isn’t possible that the AB son is biologically hers, regardless of who the father is. Ditto for the father: he can’t be the biological father. If everyone’s blood type was recorded correctly, then pretty much the only possibility is that the AB son was adopted.

It was mentioned very early in the thread- the\*\*\* incredibly\*\*\* remote possibility that the mother is, say, all of A except 1 enzyme and the father all of B except one enzyme, and they also produce the complementary for each other… Assuming that one chromosome can be both \*A-short \*and _B-complementary_, aand vice versa.

My odds are on quiet adoption, or possibly switched at birth.

[Previous page](https://boards.straightdope.com/t/ab-blood-type/623557.md?page=2)
