Airports and buildings in Denver, etc. - also similar lack of oxygen due to high altitude, or is the internal air different?

Part of a discussion of the altitude - octane argument from a prior thread of mine:

So… IMHO, a holdover from 40-50 year old figures, though there is still some effect. For that matter, most modern computer controlled ignitions will compensate to a large degree. My calculation was using the math in the video presented, at Colorado Springs altitude (6k) there was still the argument for about 1 octane’s worth of difference, but… LOTS of different information online.