# Any vaccine with very-long-term side effects? **URL:** \ **Category:** Factual Questions\ **Created:** [August 3, 2021, 5:15pm UTC](https://boards.straightdope.com/t/any-vaccine-with-very-long-term-side-effects/947976 "2021-08-03T17:15:12Z")\ **Posts on this page:** 12\ **Page:** 2
**Author:** ![Chronos](https://sea3.discourse-cdn.com/straightdope/user_avatar/boards.straightdope.com/chronos/32/134_2.png) [@Chronos](https://boards.straightdope.com/u/Chronos)\ **Post date:** [August 9, 2021, 6:45pm UTC](https://boards.straightdope.com/t/any-vaccine-with-very-long-term-side-effects/947976/21 "2021-08-09T18:45:19Z")
Really, it’s only the combination of vaccinations and tomatoes that’s dangerous. ---
**Author:** ![Hari\_Seldon](https://sea3.discourse-cdn.com/straightdope/user_avatar/boards.straightdope.com/hari_seldon/32/5173_2.png) [@Hari\_Seldon](https://boards.straightdope.com/u/Hari_Seldon)\ **Post date:** [August 10, 2021, 12:11am UTC](https://boards.straightdope.com/t/any-vaccine-with-very-long-term-side-effects/947976/22 "2021-08-10T00:11:40Z")
Only in the presence of air breathing. ---
**Author:** ![nearwildheaven](https://avatars.discourse-cdn.com/v4/letter/n/90db22/32.png) [@nearwildheaven](https://boards.straightdope.com/u/nearwildheaven)\ **Post date:** [August 10, 2021, 10:48pm UTC](https://boards.straightdope.com/t/any-vaccine-with-very-long-term-side-effects/947976/23 "2021-08-10T22:48:42Z")
Everyone who drinks dihydrogen monoxide will eventually die, too. ---
**Author:** ![Richox](https://avatars.discourse-cdn.com/v4/letter/r/8797f3/32.png) [@Richox](https://boards.straightdope.com/u/Richox)\ **Post date:** [August 19, 2021, 10:17am UTC](https://boards.straightdope.com/t/any-vaccine-with-very-long-term-side-effects/947976/24 "2021-08-19T10:17:03Z")
What about those who don’t? ---
**Author:** ![naita](https://sea3.discourse-cdn.com/straightdope/user_avatar/boards.straightdope.com/naita/32/5862_2.png) [@naita](https://boards.straightdope.com/u/naita)\ **Post date:** [August 19, 2021, 1:54pm UTC](https://boards.straightdope.com/t/any-vaccine-with-very-long-term-side-effects/947976/25 "2021-08-19T13:54:53Z")
More important _for this specific topic_ than the doubts about the existence of this association is that these were not “very-long term” effects. They supposedly showed up in the first few months. Example from one of the studies mentioned in the linked Wikipedia article: > The reports concern children 12 to 16 years old, whose symptoms occurred one to two months after vaccination. ---
**Author:** ![naita](https://sea3.discourse-cdn.com/straightdope/user_avatar/boards.straightdope.com/naita/32/5862_2.png) [@naita](https://boards.straightdope.com/u/naita)\ **Post date:** [August 19, 2021, 1:57pm UTC](https://boards.straightdope.com/t/any-vaccine-with-very-long-term-side-effects/947976/26 "2021-08-19T13:57:01Z")
> [@Richox](#): > > What about those who don’t? They will be hospitalized and doctors will administer intravenous dihydrogen monoxide to prevent them from becoming immortal. ---
**Author:** ![Dr.Winston\_OBoogie](https://sea3.discourse-cdn.com/straightdope/user_avatar/boards.straightdope.com/dr.winston_oboogie/32/2945_2.png) [@Dr.Winston\_OBoogie](https://boards.straightdope.com/u/Dr.Winston_OBoogie)\ **Post date:** [August 19, 2021, 2:39pm UTC](https://boards.straightdope.com/t/any-vaccine-with-very-long-term-side-effects/947976/27 "2021-08-19T14:39:13Z")
> [@Richox](#): > > What about those who don’t? They became addicted in utero, so end up with severe withdrawal symptoms; severe enough to cause death. ---
**Author:** ![ExTank](https://avatars.discourse-cdn.com/v4/letter/e/35a633/32.png) [@ExTank](https://boards.straightdope.com/u/ExTank)\ **Post date:** [August 19, 2021, 7:37pm UTC](https://boards.straightdope.com/t/any-vaccine-with-very-long-term-side-effects/947976/28 "2021-08-19T19:37:38Z")
It’s in the news that Moderna is starting (going ahead with?) human trials of an HIV vaccine. My Google-Fu is work-blocked right now, so what other human trials have been done with mRNA? ---
**Author:** ![shh1313](https://sea3.discourse-cdn.com/straightdope/user_avatar/boards.straightdope.com/shh1313/32/8020_2.png) [@shh1313](https://boards.straightdope.com/u/shh1313)\ **Post date:** [August 19, 2021, 8:44pm UTC](https://boards.straightdope.com/t/any-vaccine-with-very-long-term-side-effects/947976/29 "2021-08-19T20:44:22Z")
This trial is for advanced pancreatic cancer, and lung cancer. I think there’s on for breast cancer too. Pass the info on. Good news. \>\>.\> The website [ClinicalTrials.gov](http://ClinicalTrials.gov) [https://clinicaltrials.gov/](https://clinicaltrials.gov/) provides more details about [A Study of mRNA-5671/V941 as Monotherapy and in Combination With Pembrolizumab (V941-001) - Full Text View - ClinicalTrials.gov](https://clinicaltrials.gov/ct2/show/NCT03948763)), as well as many others. You can visit the [Emerging Med Trial Finder](https://app2.emergingmed.com/lustgarten/home) for a listing of all active pancreatic cancer clinical trials. [New Trial to Find Biomarkers to Guide Treatment](https://www.curetoday.com/view/new-trial-to-find-biomarkers-to-guide-treatment) Phase II trial testing for melanoma cancer \>\> > **[First patient dosed in BioNTech Phase II trial of mRNA cancer vaccine](https://www.clinicaltrialsarena.com/news/first-patient-dosed-in-biontech-phase-ii-trial-of-mrna-cancer-vaccine/)** > > BioNTech has announced that it has commenced dosing in it's BNT111 Phase II cancer vaccine trial in advanced melanoma. Cancerous tumors phase I testing. \>\>\> > **[Medical areas of focus & Modalities - Moderna](https://www.modernatx.com/research/medical-areas-of-focus?)** > > Moderna’s medical areas of focus include infectious diseases, immuno-oncology, rare diseases, cardiovascular diseases and autoimmune disease. ''Moderna and Merck formed a [strategic alliance](https://www.modernatx.com/newsroom/press-releases/merck-and-moderna-announce-strategic-collaboration-advance-novel-mrna-based)to develop mRNA-4157 in combination with Merck’s anti-PD-1 therapy, KEYTRUDA. We are currently conducting a Phase 1 study evaluating the safety, tolerability, and immunogenicity of mRNA-4157 alone in subjects with resected solid tumors and in combination with KEYTRUDA in subjects with unresectable solid tumors (KEYNOTE-603)." ---
**Author:** ![shh1313](https://sea3.discourse-cdn.com/straightdope/user_avatar/boards.straightdope.com/shh1313/32/8020_2.png) [@shh1313](https://boards.straightdope.com/u/shh1313)\ **Post date:** [August 19, 2021, 8:52pm UTC](https://boards.straightdope.com/t/any-vaccine-with-very-long-term-side-effects/947976/30 "2021-08-19T20:52:12Z")
Currently in trial testing for non hodgkins lymphoma. It looks like we are on the cusp of curing cancer and ,any other diseases. [https://www.google.com/url?sa=t&source=web&rct=j&url=https://www.cancer.gov/news-events/cancer-currents-blog/2019/in-situ-vaccine-non-hodgkin-lymphoma&ved=2ahUKEwih45GP-r3yAhUkRTABHbcFAvYQFnoECB4QAQ&usg=AOvVaw0yGY6VnGTKjsofe60USbb3](https://www.google.com/url?sa=t&source=web&rct=j&url=https://www.cancer.gov/news-events/cancer-currents-blog/2019/in-situ-vaccine-non-hodgkin-lymphoma&ved=2ahUKEwih45GP-r3yAhUkRTABHbcFAvYQFnoECB4QAQ&usg=AOvVaw0yGY6VnGTKjsofe60USbb3) ---
**Author:** ![naita](https://sea3.discourse-cdn.com/straightdope/user_avatar/boards.straightdope.com/naita/32/5862_2.png) [@naita](https://boards.straightdope.com/u/naita)\ **Post date:** [August 19, 2021, 10:21pm UTC](https://boards.straightdope.com/t/any-vaccine-with-very-long-term-side-effects/947976/31 "2021-08-19T22:21:12Z")
> [@shh1313](#): > > Currently in trial testing for non hodgkins lymphoma. It looks like we are on the cusp of curing cancer and ,any other diseases. Trials fail all the time. “We are on the cusp of curing cancer” is a premature evaluation. ---
**Author:** ![Francis\_Vaughan](https://sea3.discourse-cdn.com/straightdope/user_avatar/boards.straightdope.com/francis_vaughan/32/3093_2.png) [@Francis\_Vaughan](https://boards.straightdope.com/u/Francis_Vaughan)\ **Post date:** [August 20, 2021, 1:17am UTC](https://boards.straightdope.com/t/any-vaccine-with-very-long-term-side-effects/947976/32 "2021-08-20T01:17:30Z")
> [@shh1313](#): > > It looks like we are on the cusp of curing cancer and ,any other diseases. These treatments are typically only for a very small subset of the broader cancer types that are named. The progress is very much one of chipping away at things. Cancers have varied treatability even within a particular type, and of may evolve aggressively, often circumventing an initial effective treatment. Turning the bodies own immune system around to recognise a cancer is one of the techniques that has long been worked on, and mRNA vaccines are one way of trying that. But there is little chance it is going to be a universal cure. Given the cancer has already evaded the immune system once - simply to exist at all - imagining that some can’t do it again is wishful thinking. mRNA technology is likely going to be an exciting area of therapies. But like all before, is unlikely to be a silver bullet. Some of the big ticket diseases that afflict us we still have little idea of the cause, let alone a treatment. [Previous page](https://boards.straightdope.com/t/any-vaccine-with-very-long-term-side-effects/947976.md?page=1)