# Are non-Lipitor cholesterol drugs just as safe?

**URL:** <https://boards.straightdope.com/t/are-non-lipitor-cholesterol-drugs-just-as-safe/467201>\
**Category:** Factual Questions\
**Created:** [October 9, 2008, 6:08pm UTC](https://boards.straightdope.com/t/are-non-lipitor-cholesterol-drugs-just-as-safe/467201 "2008-10-09T18:08:56Z")\
**Posts on this page:** 4\
**Page:** 1

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**Author:** ![teela\_brown](https://avatars.discourse-cdn.com/v4/letter/t/d9b06d/32.png) [@teela\_brown](https://boards.straightdope.com/u/teela_brown)\
**Post date:** [October 9, 2008, 6:08pm UTC](https://boards.straightdope.com/t/are-non-lipitor-cholesterol-drugs-just-as-safe/467201/1 "2008-10-09T18:08:56Z")

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My doc has me on Lipitor, which has been very effective at lowering my cholesterol. But the stuff costs me $25 a month after my insurance pays their part, and I know that the generic Lipitor is still a couple of years away. Now, Wal-Mart has that $5 prescription thing going on, but the only cholesterol drugs under this program are Lovastatin and Pravastatin.

What’s the story on this? I’d like to save some money, but my doctor thinks that Lipitor is the safest. I’ll stay with it if there’s any safety question, but what’s the conventional wisdom?

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**Author:** ![Washoe](https://avatars.discourse-cdn.com/v4/letter/w/ecae2f/32.png) [@Washoe](https://boards.straightdope.com/u/Washoe)\
**Post date:** [October 9, 2008, 6:18pm UTC](https://boards.straightdope.com/t/are-non-lipitor-cholesterol-drugs-just-as-safe/467201/2 "2008-10-09T18:18:53Z")

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Here’s a [handy reference list](http://www.hamiltonroots.com/Pharmacy/Hypercholesterolemia.htm) of the statin drugs for your perusal.

ETA:

> [@](#):
>
> After doctors and patients began switching by the millions to a cheaper alternative within the same class of drugs called simvastatin, Pfizer launched a campaign including advertisements, lobbying efforts, and a paid speaking tour by Dr. Louis W. Sullivan, a former secretary of the federal Department of Health and Human Services, to discourage the trend.[2] The main clinical advantage of Lipitor over Simvastatin is that it is not metabolised by certain liver enzymes, and thus its blood concentration is not increased when combined with grapefruit juice which inhibits these enzymes. Simvastatin patients should avoid drinking large amounts of grapefruit juice for this reason. An independent analysis showed that, at commonly prescribed doses, atorvastatin and simvastatin have no statistically significant differences in reducing cardiovascular morbidity and mortality.[8]

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**Author:** ![dolphinboy](https://sea3.discourse-cdn.com/straightdope/user_avatar/boards.straightdope.com/dolphinboy/32/330_2.png) [@dolphinboy](https://boards.straightdope.com/u/dolphinboy)\
**Post date:** [October 9, 2008, 8:09pm UTC](https://boards.straightdope.com/t/are-non-lipitor-cholesterol-drugs-just-as-safe/467201/3 "2008-10-09T20:09:09Z")

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IANAD, but I have been taking Lovastatin for years and have had good results. I used to take Lipitor but my doctor switched me over because Lovastatin was cheaper and “just as good”. YMMV 🙂

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**Author:** ![FORTRAN\_forever](https://avatars.discourse-cdn.com/v4/letter/f/f17d59/32.png) [@FORTRAN\_forever](https://boards.straightdope.com/u/FORTRAN_forever)\
**Post date:** [October 9, 2008, 10:13pm UTC](https://boards.straightdope.com/t/are-non-lipitor-cholesterol-drugs-just-as-safe/467201/4 "2008-10-09T22:13:36Z")

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I’ve been on cholesterol medication (low-level doses) for many years, and I’ve been bounced back and forth between Zocor (sp?), Lipitor, and now a Zocor-generic-equivalent (Simvastatin) based on which particular drug my health care provider at the time was willing to pay for.

Each time the HCP complained the druggist would call my doctor, who apparently said something like "yeah, sure, fine"so apparently he was OK with it.

I **have** heard that one or the other of these specific medications is medically preferred for folks who experience particular side-effects/other-problems, but apparently I’m not one of them.