This was #11 for me. I had a vague worry about “10 of them said precancerous… what if 11 is the ‘lucky’ one where they find something really bad”.
Well, #11 turned out to be lucky indeed, just the other way from what I was worried about
I have other surgery… in just over 2 weeks. I wanted this out of the way first because a) if it turned up Something Bad, it would derail the other procedure (which is also related to cancer but is preventive) and b) imagine doing a colonoscopy just a month or so after abdominal surgery!
I’ve been using compounded semaglutide (Ozempic) for almost four months. I’ve lost a shade over 30 lbs since I started. It’s made a huge difference because I’m no longer obsessing about food and not eating as much junk food. I no longer keep junk food in my desk drawer because I know I won’t eat it; there are donuts in the office and I couldn’t care less if I tried. My challenge is in eating enough protein and enough fruits and vegetables each day because I don’t want to eat at all.
Somehow Ozempic has stopped working as well for me. While I still can’t overeat as I once did, I still get cravings and slightly overeat now and then. Currently losing very slowly if at all, on 2mg for 3 weeks now.
Any pointers? I’ve lost about 15lbs but would love to get 15 more, possibly even 25 would be great.
My wife had limited initial results on Ozempic/Wegovy the ended in a stall. Switching to Mounjaro/Zepbound got things going again. It has two different active drugs in it, but a little less of either individually so the side effects were less too.
I’m down 60 lb - I plateaued out for a while then started drifting down again. 290 down to 230 …would like another 30 lb…I think.
Started on Ozempic then switched to Liraglutide when Ozempic not available.
Lots of positive outcomes for me and more to come.
Downsides - hard to keep indigestion at bay, occasional runs.
Bananas probably the best for that.
I’ve only been on lowest dose.
No food cravings except the occasional carnivore urge.
No low blood sugar headaches.
A1C in normal range …no pre-diabetes anymore.
Clothes fit better.
I did not and do not lose weight dieting or exercising tho I did in my thirties viaw exercise - not diet.
It is entirely reduced food intake due to the glutides.
I eat much much smaller portions as I just flat out time out after satiation hits…don’t want any more…no effort on my part.
Replacing muscle mass is my issue now.
I’m 77. 2 years or so on glutides and count it a success.
The former. Ozempic is a GLP-1 agonist, while Zepbound is both a GLP-1 and a GIP agonist. Two modes of action.
Retatrutide, coming maybe next year, is a triple agonist that’s in the final round of testing. It appears to be even more effective than either Ozempic or Zepbound with the side benefit that patients taking it appear to lose less muscle mass than with the current drugs.
Anyone notice a pronounced difference in Ozempic effects with the weather? Could be I’m just noticing more normal seasonal variation. In winter I’m a furnace constantly seeking fuel, less so in the summer.
I think that’s normal. Ozempic seems to restore normal appetite to many people. I think a lot of obesity is caused by an unhealthy appetite, and one of the chief effects of ozempic is to improve that.
While the video would be appropriate for some other thread, this thread is for people who have decided to take these drugs, and the video is kinda thread shitting, as well as unkind to the other participants in the thread.
I’m down 60 lb - I plateaued out for a while then started drifting down again. 290 down to 230 …would like another 30 lb…I think.
Started on Ozempic then switched to Liraglutide when Ozempic not available.
Lots of positive outcomes for me and more to come.
Downsides - hard to keep indigestion at bay, occasional runs.
Bananas probably the best for that.
I’ve only been on lowest dose.
No food cravings except the occasional carnivore urge.
No low blood sugar headaches.
A1C in normal range …no pre-diabetes anymore.
Clothes fit better.
I did not and do not lose weight dieting or exercising tho I did in my thirties via exercise - not diet.
It is entirely reduced food intake due to the glutides.
I eat much much smaller portions as I just flat out time out after satiation hits…don’t want any more…no effort on my part.
Replacing muscle mass is my issue now.
I’m 77. 2 years or so on glutides and count it a success.
Went off my glutide for 10 days after my near fatal bout with sepsis.
My food cravings came roaring back within a week…found myself cruising food things online.
Was getting silly as all I could think of was something delicious to chow down on…the very bland hospital diet didn’t help.
Bowl of porridge, one piece of toast butter and jam and endless tea for brekkie in hospital gets old.
Instead of waiting till my regular day I gave up last night and restarted the injections - immediately the cravings mostly stopped and the quick satiation restarted.
I still have a Whopper in mind later today.
I’ll add a bit of a different perspective to things.
I used Wegovy from about March 2024 through about 2 months ago. Lost about 40 lbs then plateaued. The main thing I’ve noticed is that they cut out the “food noise”, meaning that I no longer see a bag of chips, think “Mmm.. Chips!” and then proceed to eat the entire bag. I can either (at my own choice!) eat a couple or just walk on by. There isn’t that.. compulsive aspect anymore. It’s really odd- I never really thought of it that way until it was gone.
Thing was, I had one episode of about 3 weeks where I had the sulfur burps, bloating, stomach pain, and eventually a violent diarrhea. Then I was fine and have remained there ever since.
I suppose that to some degree, I just adjusted my eating to match what my stomach felt like in terms of fullness, and that may have mitigated many of the side effects. But I haven’t had any side effects that weren’t there pre-GLP1 inhibitor. So if I eat too much pizza too late, I’ll still get heartburn in the wee hours of the morning, just like before. The only change is what “too much” is.
Now my Dr. has put me on Zepbound, and the annoying part of that is you start back with the lowest dosage and ramp up. So I’ve had a month or so of more hunger pangs and food noise than I’m used to, but I haven’t gained weight as far as I can tell. My hope is that on the higher dosages, I’ll get back to losing weight and go down another pants size. That would make me really happy!
That doesn’t sound right. When my wife’s doctor switched her from Ozempic to Zepbound, she went to the equivalent dose on the ladder, not back to the start. I see the same in the discussions on the support groups I’m in.
Yeah, not suggesting this is on you. I certainly have no specific expertise. Just relaying a couple anecdotes. Maybe because my wife was still only one one of the lower Wegovy/Ozempic doses (not the starter dose) it was more strightforward to switch. Dunno.
