# At Last! Sharks with Lasers, for Real! ..Oh, wait...Zebrafish?

**URL:** <https://boards.straightdope.com/t/at-last-sharks-with-lasers-for-real-oh-wait-zebrafish/948171>\
**Category:** Miscellaneous and Personal Stuff I Must Share\
**Created:** [August 6, 2021, 11:49pm UTC](https://boards.straightdope.com/t/at-last-sharks-with-lasers-for-real-oh-wait-zebrafish/948171 "2021-08-06T23:49:59Z")\
**Posts on this page:** 5\
**Page:** 1

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**Author:** ![CalMeacham](https://sea3.discourse-cdn.com/straightdope/user_avatar/boards.straightdope.com/calmeacham/32/35_2.png) [@CalMeacham](https://boards.straightdope.com/u/CalMeacham)\
**Post date:** [August 6, 2021, 11:49pm UTC](https://boards.straightdope.com/t/at-last-sharks-with-lasers-for-real-oh-wait-zebrafish/948171/1 "2021-08-06T23:49:59Z")

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At the 2021 Biophotonics Congress they presented a paper on implanting tiny lasers in Zebrafish.

But not because it was cool. They were using them to measure heart rates.

Maybe they’ll eventually move on to monitoring sharks.

Here’s a report on it:

> [@](#):
>
> ## Tissue-Integrated Microlasers Used to Measure Contraction in Beating Heart of Zebrafish
> 
> WASHINGTON — Researchers have shown that tiny lasers integrated into heart muscle cells or tissue can be used to acquire high-resolution measurements of contractility in heart muscle cells, live zebrafish and living heart tissue at locations several times deeper than other light-based techniques. The ability to characterize the contractile properties of single cells in the beating heart could improve our understanding of heart diseases and help advance new therapies.
> 
> Marcel Schubert from the [University of St. Andrews](https://www.st-andrews.ac.uk/), UK will present the research at the all-virtual 2021 [OSA Biophotonics Congress: Optics in the Life Sciences](https://www.osa.org/en-us/meetings/osa_meetings/osa_biophotonics_congress/schedule/) to be held 12-16 April. The presentation is scheduled for Wednesday, 14 April at 11:30 PDT (UTC-07:00).
> 
> “Microscopic lasers can reveal biophysical signals deep within tissue where imaging methods can’t be applied,” said Schubert. "In the future, this technique could help to overcome the increasing burden of cardiovascular diseases by guiding the development of artificial cardiac tissue and regenerative cardiac therapies.”

> **[Tissue-Integrated Microlasers Used to Measure Contraction in Beating Heart of...](https://www.optica.org/about/newsroom/news_releases/2021/tissue-integrated_microlasers_used_to_measure_contraction_in_beating_heart_of_zebrafish/)**
>
> Optica is the leading society in optics and photonics. Quality information and inspiring interactions through publications, meetings, and membership.

> **[Tissue-Integrated Microlasers Measure Beating Heart of Zebra Fish](https://www.photonics.com/Articles/Tissue-Integrated_Microlasers_Measure_Beating/a66881)**
>
> An imaging method developed by researchers at the University of St. Andrews aims to overcome difficulties in analyzing and imaging the beating he

The actual paper:

Schubert, Marcel, Lewis Woolfson, Isla RM Barnard, Amy M. Dorward, Becky Casement, Soraya Caixeiro, Andrew Morton et al. “Deep tissue contractility sensing with biointegrated microlasers.” In _Novel Techniques in Microscopy_ , pp. NW3C-2. Optical Society of America, 2021.

> **[Deep tissue contractility sensing with biointegrated microlasers](https://opg.optica.org/abstract.cfm?uri=NTM-2021-NW3C.2)**
>
> Characterizing single cell contractility in the beating heart is strongly limited by light scattering and extreme tissue dynamics. Here, we use tissue-integrated microlasers to measure contractility in live zebrafish and living myocardial slices at a...

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**Author:** ![mbh](https://avatars.discourse-cdn.com/v4/letter/m/a6a055/32.png) [@mbh](https://boards.straightdope.com/u/mbh)\
**Post date:** [August 6, 2021, 11:54pm UTC](https://boards.straightdope.com/t/at-last-sharks-with-lasers-for-real-oh-wait-zebrafish/948171/2 "2021-08-06T23:54:44Z")

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Scott Evil will be proud.

But is it a **frikking** laser?

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**Author:** ![carnivorousplant](https://sea3.discourse-cdn.com/straightdope/user_avatar/boards.straightdope.com/carnivorousplant/32/3563_2.png) [@carnivorousplant](https://boards.straightdope.com/u/carnivorousplant)\
**Post date:** [August 7, 2021, 1:11am UTC](https://boards.straightdope.com/t/at-last-sharks-with-lasers-for-real-oh-wait-zebrafish/948171/3 "2021-08-07T01:11:34Z")

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People have been messing with zebra fish for some time. Harmless little aquarium residents.  
They were being filled with fluorescent dye at some point to trace something about flooding in Florida.  
[Zebra Longfin Danio: Tropical Fish for Freshwater Aquariums (liveaquaria.com)](https://www.liveaquaria.com/product/2741/zebra-longfin-danio?pcatid=2741&c=881+2741)

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**Author:** ![dropzone](https://sea3.discourse-cdn.com/straightdope/user_avatar/boards.straightdope.com/dropzone/32/7515_2.png) [@dropzone](https://boards.straightdope.com/u/dropzone)\
**Post date:** [August 7, 2021, 2:10am UTC](https://boards.straightdope.com/t/at-last-sharks-with-lasers-for-real-oh-wait-zebrafish/948171/4 "2021-08-07T02:10:46Z")

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Alas, it isn’t Archerfish, but they come equipped with water-jet cannon stupidly accurate to a full meter already. It won’t put your eye out, but your cigarette is toast.

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**Author:** ![Beckdawrek](https://sea3.discourse-cdn.com/straightdope/user_avatar/boards.straightdope.com/beckdawrek/32/3647_2.png) [@Beckdawrek](https://boards.straightdope.com/u/Beckdawrek)\
**Post date:** [August 8, 2021, 4:18am UTC](https://boards.straightdope.com/t/at-last-sharks-with-lasers-for-real-oh-wait-zebrafish/948171/5 "2021-08-08T04:18:17Z")

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Hey catfish bark like dogs.

Nature be weird.
