He plays a very sympathetic role as the cop trying to undertsand/ ultimately help Thelma & Louise
I have to link to his appearance in the video for Weapon of Choice by Fatboy Slim. There are a couple of occasions where they use a stunt double, but those are obvious (any leaps, pretty much).
He played a sweet dad in The Wedding Planner and has had comedy roles on TV.
Jason Isaacs was a regular guy with marital problems with Catherine Keener in Friends with Money. It was weird to see him as a regular modern human after The Patriot.