At least 2001, The Martian, Gravity, Moon, Close Encounters, and Ex Machina tried. The Black Mirror series is another attempt to look at the implications of science and technology.
But not outstanding enough to be nominated before K-Pax. 
The blight was ill-thought out. The fact the yahoos had plenty of gasoline for their trucks, even though much of mankind had died, was silly. The idea that the best solution would be a self-contained space station was bonkers (especially one created in a world where children were taught that science was verboten). The “love is the most powerful force” musings of Ms. Hathaway was banal and cliched. And on, and on, and on.
At the risk of being redundant, my top five, in order:
*2001: A Space Odyssey
Forbidden Planet
Inception* (the best Philip K. Dick story that he never wrote)
War of the Worlds (the 1953 version; not to diss Spielberg’s effort)
Aliens
Anyone who ever gets around to lensing a decent version one of Ian M. Banks’ Culture novels will have a good shot at getting my vote.
Time Travel: Terminator I (perfect loop; the rest should not have been made)
Humanized Tech: Blade Runner (what does it mean to be Human?)
Inside the Brain: Inception ("…or am I a butterfly dreaming I’m a man?") or Total Recall (what is memory/dream)
Earth’s Humanity’s Future: Serenity, with or without *FireFly *behind it. (though not very optimistic about authority’s behaviors)
Visitor(s) from Space: Close Encounters of the Third Kind and/or E.T. (though – well, see above)
Life Beyond Earth: Planet of the Apes ? 
Dune ? Perhaps Avatar (even though it was Ferngully in Space).
Parallel Dimensions: The One (no, it was BAD; I only watched it because it’s a Jet Li martial arts flick).
–G!
I think They Live is the best Philip K. Dick movie that didn’t actually come from anything by Philip K. Dick.
I like it precisely for the reasons the Uniqueorn mentions. Things like the layout of his dwelling, the way police can check on the inside of the dwelling without opening the door, the way traffic was handled, things like that.
To add to Dropo’s list of monster movies, one that is rarely mentioned but that I like is The Monolith Monsters. Just alien rocks, that grow hugely tall and then fall over, shatter and the pieces start growing again, all based on contact with water (sort of the reverse of Day of the Triffids) and no discernible intelligence. People either get crushed or turned into stone. I don’t remember how the people won this one, it was something clever I think.