# Blood Types and Genetics

**URL:** <https://boards.straightdope.com/t/blood-types-and-genetics/189227>\
**Category:** Factual Questions\
**Created:** [July 17, 2003, 8:47pm UTC](https://boards.straightdope.com/t/blood-types-and-genetics/189227 "2003-07-17T20:47:30Z")\
**Posts on this page:** 11\
**Page:** 1

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**Author:** ![biddee](https://avatars.discourse-cdn.com/v4/letter/b/839c29/32.png) [@biddee](https://boards.straightdope.com/u/biddee)\
**Post date:** [July 17, 2003, 8:47pm UTC](https://boards.straightdope.com/t/blood-types-and-genetics/189227/1 "2003-07-17T20:47:30Z")

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Is it possible for two A blood type parents to have an O child? And if so, how does that work. I had always assumed that an A- mother and an A+ father have two possibities when the child is born, A- or A+. I read a post on a pregnancy message board talking about rhesus factors where one woman said that she was A- and hubby was A+ and they have two O+ daughter and one A+ son. Does her hubby need to worry that the first two daughters aren’t his?

Thanks:confused:

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**Author:** ![Earl\_Snake-Hips\_Tucker](https://sea3.discourse-cdn.com/straightdope/user_avatar/boards.straightdope.com/earl_snake-hips_tucker/32/3269_2.png) [@Earl\_Snake-Hips\_Tucker](https://boards.straightdope.com/u/Earl_Snake-Hips_Tucker)\
**Post date:** [July 17, 2003, 8:55pm UTC](https://boards.straightdope.com/t/blood-types-and-genetics/189227/2 "2003-07-17T20:55:21Z")

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Yes. The “O” gene is recessive. So a person with type A or B can also have an “O” gene from the other parent.

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**Author:** ![Earl\_Snake-Hips\_Tucker](https://sea3.discourse-cdn.com/straightdope/user_avatar/boards.straightdope.com/earl_snake-hips_tucker/32/3269_2.png) [@Earl\_Snake-Hips\_Tucker](https://boards.straightdope.com/u/Earl_Snake-Hips_Tucker)\
**Post date:** [July 17, 2003, 8:56pm UTC](https://boards.straightdope.com/t/blood-types-and-genetics/189227/3 "2003-07-17T20:56:41Z")

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This also means that _both_ parents have to be carrying the recessive “O” gene.

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**Author:** ![Dogface](https://avatars.discourse-cdn.com/v4/letter/d/9d8465/32.png) [@Dogface](https://boards.straightdope.com/u/Dogface)\
**Post date:** [July 17, 2003, 8:56pm UTC](https://boards.straightdope.com/t/blood-types-and-genetics/189227/4 "2003-07-17T20:56:48Z")

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- and - refer to Rh type. Somebody who is Rh- is homozygous recessive. Rh+ could be homozygous dominant or heterozygous, so a + and - mating could produce either + or - children.

Blood type genotypes vs. phenotypes:

Genotype Phenotype  
aa A  
a0 A  
bb B  
b0 B  
ab AB  
00 O

Blood typing is an extremely simple genetic system.

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**Author:** ![Q.E.D](https://avatars.discourse-cdn.com/v4/letter/q/51bf81/32.png) [@Q.E.D](https://boards.straightdope.com/u/Q.E.D)\
**Post date:** [July 17, 2003, 8:58pm UTC](https://boards.straightdope.com/t/blood-types-and-genetics/189227/5 "2003-07-17T20:58:27Z")

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A person with type A blood has one type A gene and one type O gene. A person with type B blood has one B gene and one O gene. Thus two people with type A or B blood (or one of each) have a 25% chance of having a child with type O blood (two O genes). A mixed couple with an A parent and a B parent also have a 25% chance of having an AB child (one A gene and one B gene).

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**Author:** ![biddee](https://avatars.discourse-cdn.com/v4/letter/b/839c29/32.png) [@biddee](https://boards.straightdope.com/u/biddee)\
**Post date:** [July 17, 2003, 8:58pm UTC](https://boards.straightdope.com/t/blood-types-and-genetics/189227/6 "2003-07-17T20:58:31Z")

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Thank you…that’s good to know…so if the O gene is recessive and my bf is O+ and I know for a fact that both my parents were A, does that mean I’ll have an A baby?

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**Author:** ![Q.E.D](https://avatars.discourse-cdn.com/v4/letter/q/51bf81/32.png) [@Q.E.D](https://boards.straightdope.com/u/Q.E.D)\
**Post date:** [July 17, 2003, 9:02pm UTC](https://boards.straightdope.com/t/blood-types-and-genetics/189227/7 "2003-07-17T21:02:23Z")

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> [@](#):
>
> \*Originally posted by biddee \*  
> \*\*Thank you…that’s good to know…so if the O gene is recessive and my bf is O+ and I know for a fact that both my parents were A, does that mean I’ll have an A baby? \*\*

Knowing only that both your parents were A type means that you are either A or O type. If you are O, you and your boyfriend have a 100% chance of having an O baby. If you are A, you and he have a 50% chance of having an O baby.

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**Author:** ![Annie-Xmas](https://avatars.discourse-cdn.com/v4/letter/a/ecc23a/32.png) [@Annie-Xmas](https://boards.straightdope.com/u/Annie-Xmas)\
**Post date:** [July 17, 2003, 9:06pm UTC](https://boards.straightdope.com/t/blood-types-and-genetics/189227/8 "2003-07-17T21:06:03Z")

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If one of your A parents was O recessive, you could be carrying the O recessive gene. If you are the chances only 1/4 for an A child (with a recessive O gene), vs. 3/4 for an O child.

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**Author:** ![biddee](https://avatars.discourse-cdn.com/v4/letter/b/839c29/32.png) [@biddee](https://boards.straightdope.com/u/biddee)\
**Post date:** [July 17, 2003, 9:07pm UTC](https://boards.straightdope.com/t/blood-types-and-genetics/189227/9 "2003-07-17T21:07:48Z")

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Q.E.D. I am A, sorry, forgot to put that in my post. So even though my parents were both A, that doesn’t mean that I am AA, I could be AO? I think I’m getting it now…sorry to be so dense…thank you for your time.

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**Author:** ![Annie-Xmas](https://avatars.discourse-cdn.com/v4/letter/a/ecc23a/32.png) [@Annie-Xmas](https://boards.straightdope.com/u/Annie-Xmas)\
**Post date:** [July 17, 2003, 9:21pm UTC](https://boards.straightdope.com/t/blood-types-and-genetics/189227/10 "2003-07-17T21:21:57Z")

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Yes. One or both of your parents could be AO, and you could have gotten the recessive gene. If you’re O, you know you are OO (no A or B genes), or if you’re AB, you know you are AB (no O genes). A’s and B’s could have recessive O’s.

In the above example, it shoukld be 50/50 of either A or O. My mistake, the four options are AO, OO, AO, or AO. :smack:

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**Author:** ![Colibri](https://sea3.discourse-cdn.com/straightdope/user_avatar/boards.straightdope.com/colibri/32/1841_2.png) [@Colibri](https://boards.straightdope.com/u/Colibri)\
**Post date:** [July 17, 2003, 9:44pm UTC](https://boards.straightdope.com/t/blood-types-and-genetics/189227/11 "2003-07-17T21:44:17Z")

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> [@](#):
>
> \*Originally posted by biddee \*  
> \*\*Q.E.D. I am A, sorry, forgot to put that in my post. So even though my parents were both A, that doesn’t mean that I am AA, I could be AO? I think I’m getting it now…sorry to be so dense…thank you for your time. \*\*

To elaborate a little more:

Since you don’t know your parents’ genotype, but only their phenotype (A), several possibilities exist:

If they are both genotype AA, then you would have a 100% chance of being AA.

If one is AA and the other AO, then you would have a 50% chance of being AA and 50% of being AO.

If both are AO, then you have a 25% chance of being AA, 50% of being AO, and 25% of being OO. (Of course, since you already know you are A phenotype, in this scenario you actually have a 33.3% chance of being AA and 66.7% chance of being AO).
