# Coronavirus COVID-19 (2019-nCoV) Thread - 2021 Breaking News

**URL:** <https://boards.straightdope.com/t/coronavirus-covid-19-2019-ncov-thread-2021-breaking-news/929428>\
**Category:** The Quarantine Zone\
**Tags:** covid-quarantine\
**Created:** [January 1, 2021, 8:03am UTC](https://boards.straightdope.com/t/coronavirus-covid-19-2019-ncov-thread-2021-breaking-news/929428 "2021-01-01T08:03:30Z")\
**Posts on this page:** 20\
**Page:** 158

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**Author:** ![Treppenwitz](https://sea3.discourse-cdn.com/straightdope/user_avatar/boards.straightdope.com/treppenwitz/32/3445_2.png) [@Treppenwitz](https://boards.straightdope.com/u/Treppenwitz)\
**Post date:** [December 5, 2021, 4:39pm UTC](https://boards.straightdope.com/t/coronavirus-covid-19-2019-ncov-thread-2021-breaking-news/929428/3204 "2021-12-05T16:39:01Z")

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> [@Snowboarder\_Bo](#):
>
> Merck gets go-ahead:  
> [US panel backs first-of-a-kind COVID-19 pill from Merck | AP News](https://apnews.com/article/coronavirus-pandemic-science-business-health-medication-6932faff66f9295417b2b1f5e02a2165)

Slow response - sorry. I dug out and have been dipping into the European Public Assessment Report for this drug (it has a conditional approval in the EU). Here it is if anyone is interested - **note that the link opens a PDF**.

> **[lagevrio-also-known-molnupiravir-or-mk-4482-covid-19-article-53-procedure-assessment-report\_en.pdf](https://www.ema.europa.eu/en/documents/referral/lagevrio-also-known-molnupiravir-or-mk-4482-covid-19-article-53-procedure-assessment-report_en.pdf)**
>
> 0 B

The reason for posting is that I happened across this _makes-you-stop-and-think_ paragraph on p 89:

> In addition, an increased mutation rate of SARS-COV-2 has been observed in molnupiravir-treated subjects compared with those given placebo, in terms of nucleotide changes in the viral RNA and their translation into amino acid changes. While this effect is expected based on the mechanism of action of this class of medicines the clinical relevance of this finding is so far not known and may require further follow-up as part of the MA. [= Marketing Authorisation, ie drug licence]

{Stops and thinks.)

j

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<div class="post-metadata">

**Author:** ![CalMeacham](https://sea3.discourse-cdn.com/straightdope/user_avatar/boards.straightdope.com/calmeacham/32/35_2.png) [@CalMeacham](https://boards.straightdope.com/u/CalMeacham)\
**Post date:** [December 5, 2021, 11:23pm UTC](https://boards.straightdope.com/t/coronavirus-covid-19-2019-ncov-thread-2021-breaking-news/929428/3205 "2021-12-05T23:23:25Z")

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Practically the entire country is red (meaning increasing numbers of reported cases, seven-day-averaged), with only four states in the blue. Several have hit record highs since last Wednesday (although, admittedly, many hit the high on Thursday):

**Vermont** 679 on Dec 2  
**New Hampshire** 1644 on Dec 2  
**Maine** 874 on Dec 3  
**Michigan** 11682 on Dec 2

Several others seemed poised to set new records; not as many as I’d feared, but we’ll see what tomorrow brings.

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**Author:** ![Snowboarder\_Bo](https://sea3.discourse-cdn.com/straightdope/user_avatar/boards.straightdope.com/snowboarder_bo/32/229_2.png) [@Snowboarder\_Bo](https://boards.straightdope.com/u/Snowboarder_Bo)\
**Post date:** [December 6, 2021, 7:19am UTC](https://boards.straightdope.com/t/coronavirus-covid-19-2019-ncov-thread-2021-breaking-news/929428/3206 "2021-12-06T07:19:46Z")

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266,140,077 total cases  
5,271,350 dead  
239,777,776 recovered

In the US:

49,969,856 total cases  
808,763 dead  
39,523,573 recovered

YesterdayA few days ago’s numbers for comparison:

> [@Snowboarder\_Bo](#):
>
> 265,196,916 total cases  
> 5,258,080 dead  
> 238,969,323 recovered
> 
> In the US:
> 
> 49,878,049 total cases  
> 808,116 dead  
> 39,463,245 recovered

---

<div class="post-metadata">

**Author:** ![CalMeacham](https://sea3.discourse-cdn.com/straightdope/user_avatar/boards.straightdope.com/calmeacham/32/35_2.png) [@CalMeacham](https://boards.straightdope.com/u/CalMeacham)\
**Post date:** [December 6, 2021, 8:31pm UTC](https://boards.straightdope.com/t/coronavirus-covid-19-2019-ncov-thread-2021-breaking-news/929428/3207 "2021-12-06T20:31:18Z")

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> [@](#):
>
> # October COVID Death Rate In Reddest Tenth Of Nation Six Times Higher Than Bluest: Report
> 
> Since May, counties that voted overwhelmingly for Trump tallied nearly triple the death rate of blue state counterparts — due to COVID “misinformation,” says NPR.
> 
> [COVID](https://www.huffpost.com/news/topic/covid-19)-related American death data [shows dramatic differences](https://www.huffpost.com/entry/red-blue-states-covid-cases-deaths-wapo_n_613d675fe4b0640100a5a973)between Republican and Democratic counties, with the reddest tenth of the nation in October [chalking up a death rate six times higher](https://www.npr.org/sections/health-shots/2021/12/05/1059828993/data-vaccine-misinformation-trump-counties-covid-death-rate) than that of the bluest tenth, NPR reported.
> 
> That radical divergence for Republican counties has since [dropped to a still startling 5.5 times higher](https://acasignups.net/21/12/02/weekly-update-covid19-casedeath-rates-county-partisan-lean-vaccination-rate), according to Charles Gaba, an independent health care analyst who has been tracking partisanship pandemic trends.

> **[October COVID Death Rate In Reddest Tenth Of Nation Six Times Higher Than...](https://www.huffpost.com/entry/red-states-high-covid-death-rates-npr-study_n_61ad43bbe4b025be1af941d3)**
>
> Since May, counties that voted overwhelmingly for Trump tallied nearly triple the death rate of blue state counterparts — due to COVID "misinformation," says NPR.

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<div class="post-metadata">

**Author:** ![Snowboarder\_Bo](https://sea3.discourse-cdn.com/straightdope/user_avatar/boards.straightdope.com/snowboarder_bo/32/229_2.png) [@Snowboarder\_Bo](https://boards.straightdope.com/u/Snowboarder_Bo)\
**Post date:** [December 7, 2021, 2:19am UTC](https://boards.straightdope.com/t/coronavirus-covid-19-2019-ncov-thread-2021-breaking-news/929428/3208 "2021-12-07T02:19:47Z")

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266,680,561 total cases  
5,277,353 dead  
240,218,807 recovered

In the US:

50,148,673 total cases  
810,244 dead  
39,669,544 recovered

Yesterday’s numbers for comparison:

> [@Snowboarder\_Bo](#):
>
> 266,140,077 total cases  
> 5,271,350 dead  
> 239,777,776 recovered
> 
> In the US:
> 
> 49,969,856 total cases  
> 808,763 dead  
> 39,523,573 recovered

---

<div class="post-metadata">

**Author:** ![ThelmaLou](https://sea3.discourse-cdn.com/straightdope/user_avatar/boards.straightdope.com/thelmalou/32/390_2.png) [@ThelmaLou](https://boards.straightdope.com/u/ThelmaLou)\
**Post date:** [December 7, 2021, 2:57am UTC](https://boards.straightdope.com/t/coronavirus-covid-19-2019-ncov-thread-2021-breaking-news/929428/3209 "2021-12-07T02:57:35Z")

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Apologies if this has been answered-- any deaths reported from omicron?

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**Author:** ![needscoffee](https://sea3.discourse-cdn.com/straightdope/user_avatar/boards.straightdope.com/needscoffee/32/1076_2.png) [@needscoffee](https://boards.straightdope.com/u/needscoffee)\
**Post date:** [December 7, 2021, 3:00am UTC](https://boards.straightdope.com/t/coronavirus-covid-19-2019-ncov-thread-2021-breaking-news/929428/3210 "2021-12-07T03:00:58Z")

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I haven’t seen any reported. So far, it looks to be relatively less severe than had been feared, if I’m following correctly.

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**Author:** ![ThelmaLou](https://sea3.discourse-cdn.com/straightdope/user_avatar/boards.straightdope.com/thelmalou/32/390_2.png) [@ThelmaLou](https://boards.straightdope.com/u/ThelmaLou)\
**Post date:** [December 7, 2021, 3:11am UTC](https://boards.straightdope.com/t/coronavirus-covid-19-2019-ncov-thread-2021-breaking-news/929428/3211 "2021-12-07T03:11:53Z")

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🤞 If only…

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**Author:** ![puzzlegal](https://sea3.discourse-cdn.com/straightdope/user_avatar/boards.straightdope.com/puzzlegal/32/3827_2.png) [@puzzlegal](https://boards.straightdope.com/u/puzzlegal)\
**Post date:** [December 7, 2021, 3:28am UTC](https://boards.straightdope.com/t/coronavirus-covid-19-2019-ncov-thread-2021-breaking-news/929428/3212 "2021-12-07T03:28:45Z")

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I’m hopeful, but deaths are a lagging indicator, and omicron is new.

> **[Omicron Update: Dec 4](https://yourlocalepidemiologist.substack.com/p/omicron-update-dec-4)**
>
> It’s hard to believe it’s been one week since Omicron broke the news. While we continue to wait on lab evidence, we’re getting a substantial amount of epidemiological data every day. Here’s an update since my last… 1. Reinfections are high against...

One alarming detail is that omicron is sending kids to the hospital. That’s new. Look at the graph about half way down that link. (Sorry, I’ve spent some time trying to make it show, and i give up.)

If I’m reading that graph right, (not the one visible in the box, but the one half way down the linked page) more than 100 kids under 5 are hospitalized in Tshwane, something that we really haven’t seen before.

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**Author:** ![eschrodinger](https://sea3.discourse-cdn.com/straightdope/user_avatar/boards.straightdope.com/eschrodinger/32/122_2.png) [@eschrodinger](https://boards.straightdope.com/u/eschrodinger)\
**Post date:** [December 7, 2021, 5:15am UTC](https://boards.straightdope.com/t/coronavirus-covid-19-2019-ncov-thread-2021-breaking-news/929428/3213 "2021-12-07T05:15:08Z")

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> [@puzzlegal](#):
>
> One alarming detail is that omicron is sending kids to the hospital. That’s new. Look at the graph about half way down that link.

That’s a really interesting article, and pretty scary graphs. In addition to the hospitalizations graph, the slopes of the new infections and reinfections spikes are unreal.

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**Author:** ![Die\_Capacitrix](https://sea3.discourse-cdn.com/straightdope/user_avatar/boards.straightdope.com/die_capacitrix/32/9_2.png) [@Die\_Capacitrix](https://boards.straightdope.com/u/Die_Capacitrix)\
**Post date:** [December 7, 2021, 6:06am UTC](https://boards.straightdope.com/t/coronavirus-covid-19-2019-ncov-thread-2021-breaking-news/929428/3214 "2021-12-07T06:06:09Z")

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[Interesting](https://businesstech.co.za/news/trending/544320/what-a-hospital-in-tshwane-is-teaching-us-about-vaccinated-vs-unvaccinated-covid-patients/):

> According to the data, 66% of patients were “incidental Covid admissions”, meaning they were for other conditions and found they were positive upon the hospital arrival.

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**Author:** ![CalMeacham](https://sea3.discourse-cdn.com/straightdope/user_avatar/boards.straightdope.com/calmeacham/32/35_2.png) [@CalMeacham](https://boards.straightdope.com/u/CalMeacham)\
**Post date:** [December 7, 2021, 4:46pm UTC](https://boards.straightdope.com/t/coronavirus-covid-19-2019-ncov-thread-2021-breaking-news/929428/3215 "2021-12-07T16:46:45Z")

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I’m happy to say that the states have mostly avoided setting new records for seven-day averaged new COVIC cases for the past few days. It was looking pretty scary in several states. But Vermont and New Hampshire haven’t set new records very recently. Nor Rhode Island, Massachusetts, or Maine. Other states have retreated from the skyrocket-like rise in new cases.

**Michigan** , however, hit a new high of 10048 yesterday, beating the previous high set Dec 2, five days ago

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**Author:** ![Senegoid](https://sea3.discourse-cdn.com/straightdope/user_avatar/boards.straightdope.com/senegoid/32/6606_2.png) [@Senegoid](https://boards.straightdope.com/u/Senegoid)\
**Post date:** [December 7, 2021, 4:56pm UTC](https://boards.straightdope.com/t/coronavirus-covid-19-2019-ncov-thread-2021-breaking-news/929428/3216 "2021-12-07T16:56:53Z")

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> [@CalMeacham](#):
>
> I’m happy to say that the states have mostly avoided setting new records for seven-day averaged new COVIC cases for the past few days.

Times are getting desperate when it’s _good_ news that somebody didn’t set a new infection record.

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**Author:** ![tofor](https://sea3.discourse-cdn.com/straightdope/user_avatar/boards.straightdope.com/tofor/32/13727_2.png) [@tofor](https://boards.straightdope.com/u/tofor)\
**Post date:** [December 7, 2021, 5:53pm UTC](https://boards.straightdope.com/t/coronavirus-covid-19-2019-ncov-thread-2021-breaking-news/929428/3217 "2021-12-07T17:53:35Z")

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> [@CalMeacham](#):
>
> I’m happy to say that the states have mostly avoided setting new records for seven-day averaged new COVIC cases for the past few days. It was looking pretty scary in several states. But Vermont and New Hampshire haven’t set new records very recently. Nor Rhode Island, Massachusetts, or Maine. Other states have retreated from the skyrocket-like rise in new cases.

It’s too soon to tell. Thanksgiving totally borked all the records. There was a couple days with way too few cases being reported, then a few days with way too many. We’re still waiting for those records to even out and show us something meaningful.

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**Author:** ![susan](https://sea3.discourse-cdn.com/straightdope/user_avatar/boards.straightdope.com/susan/32/17537_2.png) [@susan](https://boards.straightdope.com/u/susan)\
**Post date:** [December 7, 2021, 6:52pm UTC](https://boards.straightdope.com/t/coronavirus-covid-19-2019-ncov-thread-2021-breaking-news/929428/3218 "2021-12-07T18:52:39Z")

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Yes, my state just did something like a 7,000 case adjustment for November due to late reporting.

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**Author:** ![BigT](https://sea3.discourse-cdn.com/straightdope/user_avatar/boards.straightdope.com/bigt/32/12044_2.png) [@BigT](https://boards.straightdope.com/u/BigT)\
**Post date:** [December 8, 2021, 2:08am UTC](https://boards.straightdope.com/t/coronavirus-covid-19-2019-ncov-thread-2021-breaking-news/929428/3219 "2021-12-08T02:08:37Z")

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[Wapo has an article](https://www.washingtonpost.com/health/2021/12/07/omicron-escape-antibodies/). Here are important parts for those who hit the paywall:

> In a preprint paper not yet peer-reviewed, scientists in South Africa reported a large, 41-fold drop in antibodies’ virus-blocking ability — “much more extensive escape” than seen against previous variants using similar experiments. But the scientists stressed the positive element of their research: Omicron did not escape antibodies completely, and people who had been previously infected and fully vaccinated with two shots of the vaccine retained “relatively high” levels of antibodies protective against omicron.

> “Omicron evades most of the vaccine response,” said Michel C. Nussenzweig, a Rockefeller University investigator who was not part of the South Africa research team but whose experiments predicted a similar drop in antibodies’ neutralizing ability. He stopped short of saying that vaccines will have to be rebooted to match omicron’s highly mutated spike protein.
> 
> “We don’t know what will happen with hospitalization or severe disease. If vaccines are keeping people out of the hospital and are making what could be a bad disease into something like a common cold, or something a bit more severe but not life-threatening in any way, then we’re good,” Nussenzweig said.

> “Thank goodness we have some concrete data now,” Benjamin Neuman, a virologist at Texas A&M University, said in an email. He said scientists had worried that omicron would be able to elude entirely the first line of defense, the neutralizing antibodies. Not so. The lab research supports the need for boosters, he added.
> 
> “It looks like quantity of antibodies will overcome the natural resistance of omicron, and that is a very good thing,” he said. “Boosters not only let the body make more diverse antibodies, they also raise antibody levels. In other words, Omicron may be vaccine-resistant, but it is not booster-proof.”

So as not to quote more, I’ll also summarize some other bits. William Hanage, an epidemiologist at the Harvard T.H. Chan School of Public Health, says that this does not mean that having had COVID-19 is more protective on its own, only along with vaccines. And David R. Martinez, a viral immunologist at the University of North Carolina Gillings School of Global Public Health, reminds people that healthy people will likely be more protected from severe disease due to there being other aspects of the immune system besides the antibodies, and that this does not mean we’re back to square one with COVID-19.

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**Author:** ![BigT](https://sea3.discourse-cdn.com/straightdope/user_avatar/boards.straightdope.com/bigt/32/12044_2.png) [@BigT](https://boards.straightdope.com/u/BigT)\
**Post date:** [December 8, 2021, 2:14am UTC](https://boards.straightdope.com/t/coronavirus-covid-19-2019-ncov-thread-2021-breaking-news/929428/3220 "2021-12-08T02:14:08Z")

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This CNN article (which should have no paywall) seems to be about the same study, and argues that the current boosters likely still protect from severe disease, as Benjamin Neuman said.

> **[Omicron coronavirus variant partly evades Pfizer vaccine's protection, study...](https://www.cnn.com/2021/12/07/health/omicron-variant-pfizer-vaccine-south-africa-study/index.html)**
>
> The Omicron coronavirus variant partly escapes the protection offered by the Pfizer vaccine, but people who have been previously infected and then vaccinated are likely to be well protected, researchers working in South Africa reported Tuesday.

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<div class="post-metadata">

**Author:** ![Snowboarder\_Bo](https://sea3.discourse-cdn.com/straightdope/user_avatar/boards.straightdope.com/snowboarder_bo/32/229_2.png) [@Snowboarder\_Bo](https://boards.straightdope.com/u/Snowboarder_Bo)\
**Post date:** [December 8, 2021, 2:57am UTC](https://boards.straightdope.com/t/coronavirus-covid-19-2019-ncov-thread-2021-breaking-news/929428/3221 "2021-12-08T02:57:56Z")

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267,387,468 total cases  
5,286,518 dead  
240,764,886 recovered

In the US:

50,270,136 total cases  
812,205 dead  
39,742,867 recovered

Yesterday’s numbers for comparison:

> [@Snowboarder\_Bo](#):
>
> 266,680,561 total cases  
> 5,277,353 dead  
> 240,218,807 recovered
> 
> In the US:
> 
> 50,148,673 total cases  
> 810,244 dead  
> 39,669,544 recovered

---

<div class="post-metadata">

**Author:** ![Steve\_MB](https://sea3.discourse-cdn.com/straightdope/user_avatar/boards.straightdope.com/steve_mb/32/5339_2.png) [@Steve\_MB](https://boards.straightdope.com/u/Steve_MB)\
**Post date:** [December 8, 2021, 12:04pm UTC](https://boards.straightdope.com/t/coronavirus-covid-19-2019-ncov-thread-2021-breaking-news/929428/3222 "2021-12-08T12:04:11Z")

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I felt a great disturbance in the Force, as if millions of managers who want their peons back in the cubicles cried into their three-martini lunches and were suddenly silenced…

> **[Google and Uber delay office returns amid omicron uncertainty](https://www.washingtonpost.com/business/2021/12/06/omicron-return-to-office/)**
>
> Major corporations that had planned to bring all their employees back into offices in early 2022 now have to decide whether those dates make sense in light of further evidence of the pandemic’s unpredictability.

> Last week, Google and Uber became some of the first major employers in the United States to announce that they would postpone their Jan. 10 return date — not to another specific day, but indefinitely. Ford Motor Co. said Monday that it was pushing its expected return from January to March…

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<div class="post-metadata">

**Author:** ![ratatoskK](https://sea3.discourse-cdn.com/straightdope/user_avatar/boards.straightdope.com/ratatoskk/32/2987_2.png) [@ratatoskK](https://boards.straightdope.com/u/ratatoskK)\
**Post date:** [December 8, 2021, 3:49pm UTC](https://boards.straightdope.com/t/coronavirus-covid-19-2019-ncov-thread-2021-breaking-news/929428/3223 "2021-12-08T15:49:15Z")

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[https://www.nytimes.com/live/2021/12/08/world/omicron-variant-covid/pfizer-says-blood-samples-showed-a-third-dose-of-its-vaccine-provides-significant-protection-against-omicron](https://www.nytimes.com/live/2021/12/08/world/omicron-variant-covid/pfizer-says-blood-samples-showed-a-third-dose-of-its-vaccine-provides-significant-protection-against-omicron)

> Pfizer and BioNTech said Wednesday that laboratory tests suggest that three doses of their coronavirus vaccine offer significant protection against the fast-spreading Omicron variant of the virus.
> 
> The companies said that tests of blood from individuals who received only two doses found more than a 25-fold reduction in antibody levels against the Omicron variant compared to an earlier version of the virus. That finding indicates that two doses alone “may not be sufficient to protect against infection” by the new variant, the companies said.

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