# Coronavirus general discussion and chit-chat

**URL:** <https://boards.straightdope.com/t/coronavirus-general-discussion-and-chit-chat/917903>\
**Category:** The Quarantine Zone\
**Tags:** covid-quarantine\
**Created:** [August 12, 2020, 5:29pm UTC](https://boards.straightdope.com/t/coronavirus-general-discussion-and-chit-chat/917903 "2020-08-12T17:29:38Z")\
**Posts on this page:** 1\
**Showing post:** 1570

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**Author:** ![puzzlegal](https://sea3.discourse-cdn.com/straightdope/user_avatar/boards.straightdope.com/puzzlegal/32/3827_2.png) [@puzzlegal](https://boards.straightdope.com/u/puzzlegal)\
**Post date:** [May 21, 2022, 5:55pm UTC](https://boards.straightdope.com/t/coronavirus-general-discussion-and-chit-chat/917903/1570 "2022-05-21T17:55:21Z")

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Can you elaborate on this:

> [@How's Florida for Covid right now? Need input regarding possible business trip soon-ish](https://boards.straightdope.com/t/hows-florida-for-covid-right-now-need-input-regarding-possible-business-trip-soon-ish/964677/25):
>
> and the open reading frame (ORF) proteins, particularly ORF8, appear to be largely dictating the pathogenicity of the virus

(Clipped from a different thread.)

I haven’t seen much on research into what makes this virus more or less damaging, and I’m curious.

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