# Could the placenta continue to function?

**URL:** <https://boards.straightdope.com/t/could-the-placenta-continue-to-function/736909>\
**Category:** Factual Questions\
**Created:** [November 7, 2015, 4:34pm UTC](https://boards.straightdope.com/t/could-the-placenta-continue-to-function/736909 "2015-11-07T16:34:02Z")\
**Posts on this page:** 20\
**Page:** 7

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**Author:** ![Nullpersona](https://avatars.discourse-cdn.com/v4/letter/n/b5ac83/32.png) [@Nullpersona](https://boards.straightdope.com/u/Nullpersona)\
**Post date:** [November 17, 2015, 9:03am UTC](https://boards.straightdope.com/t/could-the-placenta-continue-to-function/736909/121 "2015-11-17T09:03:20Z")

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> [@KarlGrenze](#):
>
> Eh, no, the diagram is flawed. What that picture is pointing out is the placental fetal/maternal attachment site. The placenta is the whole sac that contains the fetus.
> 
> You’ve failed to properly see the pictures and other diagrams provided, or to carefully read and understand what is written.
> 
> Eh, nope… check the diagram. I think you’re confusing the placental fetal/maternal exchange part with the whole placenta (the attachment site). The umbilical vessels (and urachus) run from the abdomen to the placental attachment site (or placenta in non-discoid placental animals).
> 
> Stop treating the placenta as if it is solely a human thing. It is not, it happens in all mammalian species.
> 
> Your logic is unorthodox, flawed, and incorrect.

This is an impasse.

I will continue to be educated, and perhaps find I am in error.

Barring that, we have nothing further to discuss.

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**Author:** ![Nullpersona](https://avatars.discourse-cdn.com/v4/letter/n/b5ac83/32.png) [@Nullpersona](https://boards.straightdope.com/u/Nullpersona)\
**Post date:** [November 17, 2015, 9:13am UTC](https://boards.straightdope.com/t/could-the-placenta-continue-to-function/736909/122 "2015-11-17T09:13:51Z")

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> **[Amniotic sac](https://en.wikipedia.org/wiki/Amniotic_sac)**
>
> The amniotic sac, also called the bag of waters or the membranes, is the sac in which the embryo and later fetus develops in amniotes. It is a thin but tough transparent pair of membranes that hold a developing embryo (and later fetus) until shortly before birth. The inner of these membranes, the amnion, encloses the amniotic cavity, containing the amniotic fluid and the embryo. The outer membrane, the chorion, contains the amnion and is part of the placenta. On the outer side, the amnio The yolk...

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**Author:** ![Bryan\_Ekers](https://sea3.discourse-cdn.com/straightdope/user_avatar/boards.straightdope.com/bryan_ekers/32/183_2.png) [@Bryan\_Ekers](https://boards.straightdope.com/u/Bryan_Ekers)\
**Post date:** [November 17, 2015, 10:01am UTC](https://boards.straightdope.com/t/could-the-placenta-continue-to-function/736909/123 "2015-11-17T10:01:18Z")

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> [@Nullpersona](#):
>
> What causes the placenta to stop working?

Unfair labor conditions.

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**Author:** ![Oly](https://sea3.discourse-cdn.com/straightdope/user_avatar/boards.straightdope.com/oly/32/8255_2.png) [@Oly](https://boards.straightdope.com/u/Oly)\
**Post date:** [November 17, 2015, 11:16am UTC](https://boards.straightdope.com/t/could-the-placenta-continue-to-function/736909/124 "2015-11-17T11:16:34Z")

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There’s a philosophical angle to all this, but there’s also a practical one. Philosophically, everything seems to indicate, as said upthread, that the placenta has evolved to function as a temporary organ. If there was some advantage to retain it, at least in the rough and tumble evolutionary environment that has accompanied us up to now, it would have been done. To quote Jeff Goldblum from the original (and IMHO the best) Jurassic Park movie “Life, uh, finds a way.”

That’s not to say, however, that it could not be done otherwise. To paraphrase Jeff Goldblum, “Humans find a way.” If someone really wanted to keep the placenta chugging along (really more like slurping, I suppose) - attached at one end, the other or both - I would (and here I quote my mom) “bet dollars to donuts” they could. To say flat out that it can’t be done, or that the placenta is somehow _destined_ to whither and die in the same way it does now, is, again, philosophically speaking, unscientific. Biology is mechanistic. Mechanisms can be manipulated.

This is where we get into the practical part, using “practical” in the broad sense of now you’d actually have to do something. You’d have to do some research, some experimenting. You’d need money. Lots I assume. That means you’d have to convince other people you’ve got some good ideas, and a plan, and a goal. Lots of furry critters and their un- and newborn offspring would be sacrificed. A lot of grad students would earn PhDs. And, who knows, maybe someone would win a Nobel Prize.

Sounds like, from the linked article way back when, some of that is already going on.

I don’t know where you are on your life’s journey, **Nullpersona** , but if you are looking for a direction, or for something on which to focus, with your obvious interest and, shall we say, inobvious points of view, you might want to consider getting in on some of that action.

It would seem to be a symbiotic relationship waiting to happen.

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**Author:** ![Jackmannii](https://sea3.discourse-cdn.com/straightdope/user_avatar/boards.straightdope.com/jackmannii/32/311_2.png) [@Jackmannii](https://boards.straightdope.com/u/Jackmannii)\
**Post date:** [November 17, 2015, 1:10pm UTC](https://boards.straightdope.com/t/could-the-placenta-continue-to-function/736909/125 "2015-11-17T13:10:43Z")

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Carrying on the plant analogy, why aren’t seed capsules/fruits a permanent entity unto themselves, instead of temporary receptacles for developing embryos?

Don’t eat that fruit, killer!

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**Author:** ![Chief\_Pedant](https://avatars.discourse-cdn.com/v4/letter/c/a6a055/32.png) [@Chief\_Pedant](https://boards.straightdope.com/u/Chief_Pedant)\
**Post date:** [November 17, 2015, 2:34pm UTC](https://boards.straightdope.com/t/could-the-placenta-continue-to-function/736909/126 "2015-11-17T14:34:58Z")

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> [@Nullpersona](#):
>
> Chief Pedant provided proof of the placenta’s functionality up to birth.

Chief Pedant IS proof of the placenta’s functionality up to birth.

But to keep it going indefinitely, you need a uterus on one side, which means you need a Mom to support the uterus, and you need a baby on the other, since the placenta is essentially a fetal organ.

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**Author:** ![WhyNot](https://avatars.discourse-cdn.com/v4/letter/w/c77e96/32.png) [@WhyNot](https://boards.straightdope.com/u/WhyNot)\
**Post date:** [November 17, 2015, 3:00pm UTC](https://boards.straightdope.com/t/could-the-placenta-continue-to-function/736909/127 "2015-11-17T15:00:13Z")

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What the OP keeps ignoring is that, _even if the placenta stays inside the uterus_, it begins to die. Apoptosis, programmed cell death, happens in all cells except cancerous ones, but it happens more quickly in placental cells than in most others.

I do understand some of what the OP and others are saying, in terms of how it would be really neat, and possibly lifesaving for premature infants\*, if we could transplant the placenta into some other growth medium that would allow it to continue to function. What the OP seems to stubbornly refuse is that s/he’s talking about far more than changing the environment of the placenta. In order for this to work, s/he needs to change the very \*nature \*of the placenta, the structure and function of the placenta.

Could technology get us there someday? Sure. Anything is possible. But if you do it, you’re going to have a cancerous mass that shares a passing resemblance to a placenta. You won’t have a placenta in its current form.

The placenta cannot continue to function, which was the original question. You may be able to, someday, create an artificial placenta with placental tissue. Different question.

\*Happy National Prematurity Day, by the way!

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**Author:** ![KarlGrenze](https://avatars.discourse-cdn.com/v4/letter/k/dbc845/32.png) [@KarlGrenze](https://boards.straightdope.com/u/KarlGrenze)\
**Post date:** [November 17, 2015, 3:36pm UTC](https://boards.straightdope.com/t/could-the-placenta-continue-to-function/736909/128 "2015-11-17T15:36:49Z")

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> [@Nullpersona](#):
>
> [Amniotic sac - Wikipedia](https://en.wikipedia.org/wiki/Amniotic_sac)

Note that the amniotic sac is inside the chorionic sac, both of which are component of the placenta. What many people seem to visualize as placenta is the exact attachment site, which like **WhyNot** mentioned is a mesh of fetal and maternal tissues exchanging nutrients and wastes. Without this meshwork the placenta cannot work.

Please also note that this attachment is expelled by the uterus. It is not removed artificially, but nature itself decrees that the attachment must stop and the placenta must be expelled as it is no longer needed.

You could refer to the paragraph in that same link that mentions that the amnion is the inner part, the chorion the outer part, and both are part of the placenta.

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**Author:** ![Mangetout](https://sea3.discourse-cdn.com/straightdope/user_avatar/boards.straightdope.com/mangetout/32/19_2.png) [@Mangetout](https://boards.straightdope.com/u/Mangetout)\
**Post date:** [November 17, 2015, 7:52pm UTC](https://boards.straightdope.com/t/could-the-placenta-continue-to-function/736909/129 "2015-11-17T19:52:31Z")

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> [@Nullpersona](#):
>
> I stated the question had been answered.
> 
> The discussion continues.
> 
> You may choose not to participate.  
> Could the placenta have become vestigial? Not as long as humans are being born.  
> Your arguments have merit, but are assuming that the placenta decides to die instantly at birth.

Humans are not the only animals to have placentas. All placental mammals have them - mice, moose, monkeys; ermine, elk, elephants. Without exception, they discard (or recycle) the placenta once the offspring are born.

> [@](#):
>
> There is cause and effect for everything.
> 
> What causes the placenta to stop working?

Separation from the uterus. It’s not capable of independent function.

> [@](#):
>
> Have we adapted to shut them off? Possibly.
> 
> Do you have any proof of that specific genetic evolution?

Is not even a question that makes sense.

> [@](#):
>
> When very-likely and probably are the extent of your certitude, it is conjecture.

Biology is a science, not a collection of fuzzy guesses. You can study the function of the placenta in very great detail - either for yourself, or by proxy (e.g. read a biology reference book). You clearly haven’t done this, or you wouldn’t be promoting this fanciful, worthless idea.

> [@](#):
>
> I would drop it like a bad habit, if it weren’t true. Wouldn’t you?

I don’t really understand this sentence, but if you’re arguing that you are open to persuasion, I see no evidence of that.

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<div class="post-metadata">

**Author:** ![gigi](https://avatars.discourse-cdn.com/v4/letter/g/a587f6/32.png) [@gigi](https://boards.straightdope.com/u/gigi)\
**Post date:** [November 17, 2015, 11:06pm UTC](https://boards.straightdope.com/t/could-the-placenta-continue-to-function/736909/130 "2015-11-17T23:06:39Z")

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> [@KarlGrenze](#):
>
> Eh, no, the diagram is flawed. What that picture is pointing out is the placental fetal/maternal attachment site. The placenta is the whole sac that contains the fetus.

Can you describe the typical mechanics with respect to a routine vaginal delivery? How close am I: Sac breaks, amniotic fluid pours out, baby is delivered, umbilical cord is connected to “attachment site”. Does the “attachment site” aka dark red blob get delivered, and then what… the whole sac is delivered on the blob’s tail, like inside out? I’ve only ever seen footage of the dark red blob being delivered into the dish.

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<div class="post-metadata">

**Author:** ![KarlGrenze](https://avatars.discourse-cdn.com/v4/letter/k/dbc845/32.png) [@KarlGrenze](https://boards.straightdope.com/u/KarlGrenze)\
**Post date:** [November 17, 2015, 11:16pm UTC](https://boards.straightdope.com/t/could-the-placenta-continue-to-function/736909/131 "2015-11-17T23:16:01Z")

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> [@gigi](#):
>
> Can you describe the typical mechanics with respect to a routine vaginal delivery? How close am I: Sac breaks, amniotic fluid pours out, baby is delivered, umbilical cord is connected to “attachment site”. Does the “attachment site” aka dark red blob get delivered, and then what… the whole sac is delivered on the blob’s tail, like inside out? I’ve only ever seen footage of the dark red blob being delivered into the dish.

Look closely at the pictures under the Wiki’s entry of placenta. You’ll see a very very thin membrane around the “red blob”. That is the rest of the placenta (placentas, other than the attachment places, are very very thin). But parts may break (thin material). In humans and most animals, the important thing is that the attachment places themselves are removed. Remains are bad for a variety of reasons.

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**Author:** ![WhyNot](https://avatars.discourse-cdn.com/v4/letter/w/c77e96/32.png) [@WhyNot](https://boards.straightdope.com/u/WhyNot)\
**Post date:** [November 18, 2015, 12:06am UTC](https://boards.straightdope.com/t/could-the-placenta-continue-to-function/736909/132 "2015-11-18T00:06:11Z")

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I think this page is better than wikipedia. [The Placenta](http://www.sharinginhealth.ca/biology/placenta.html)

The fleshy red part that most people think of as “the placenta” is part of a part called _the decidua_. There are actually three parts even to that part. Everything that comes out of the mother before, during, and after birth, except for the baby, is all, collectively, “the placenta”, if you’re a scientist. The sacs, the umbilical cord, the amniotic liquid, the decidua…all parts of “the placenta”.

Most of us in this thread have been using the common meaning of _placenta_, referring to the decidua. But \*\*KarlGrenze \*\*is definitely correct.

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**Author:** ![KarlGrenze](https://avatars.discourse-cdn.com/v4/letter/k/dbc845/32.png) [@KarlGrenze](https://boards.straightdope.com/u/KarlGrenze)\
**Post date:** [November 18, 2015, 12:39am UTC](https://boards.straightdope.com/t/could-the-placenta-continue-to-function/736909/133 "2015-11-18T00:39:44Z")

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> [@WhyNot](#):
>
> Most of us in this thread have been using the common meaning of _placenta_, referring to the decidua. But \*\*KarlGrenze \*\*is definitely correct.

I deal with non-human placentas, and they look different. The majority of species do not have the discoid shaped deciduas (hoped I used the term correctly). So for me, that red blob is the attachment site, and part of the placenta, and it would look strikingly different if it were a dog, a horse, a pig, or a cow (they would also work and attach differently).

🙂 Thanks for reminding that what for me is clear as water is not for others. 🙂

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**Author:** ![Oly](https://sea3.discourse-cdn.com/straightdope/user_avatar/boards.straightdope.com/oly/32/8255_2.png) [@Oly](https://boards.straightdope.com/u/Oly)\
**Post date:** [November 18, 2015, 12:49am UTC](https://boards.straightdope.com/t/could-the-placenta-continue-to-function/736909/134 "2015-11-18T00:49:12Z")

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> [@WhyNot](#):
>
> \*Happy National Prematurity Day, by the way!

Thanks. I celebrated yesterday.

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**Author:** ![Leo\_Bloom](https://sea3.discourse-cdn.com/straightdope/user_avatar/boards.straightdope.com/leo_bloom/32/10377_2.png) [@Leo\_Bloom](https://boards.straightdope.com/u/Leo_Bloom)\
**Post date:** [November 18, 2015, 9:28pm UTC](https://boards.straightdope.com/t/could-the-placenta-continue-to-function/736909/135 "2015-11-18T21:28:33Z")

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Was this SerenDipitous news item mentioned upthread?:  
_Surgery Could Give Men Wombs of Their Own Within 5 Years_  
…last week’s announcement that the Cleveland Clinic is performing uterus transplant surgery on women who were born without a womb or whose uterus is diseased or malfunctioning…

Uterus transplants are still in the research stage for women suffering from uterine factor infertility (UFI). A Swedish team already has successfully transplanted uteri harvested from live donors and achieved five pregnancies and four live births. In the coming months, the Cleveland Clinic team plans to transplant uteri from deceased donors into UFI female patients…

However, biological women have a leg up on biological males when it comes to accepting and nurturing a transplanted uterus. Women already have: vasculature needed to feed the uterus with blood, pelvic ligaments designed to support a uterus, a vagina and cervix, and natural hormones that prepare the uterus for implantation and support the pregnancy…

> **[Surgery Could Give Men Wombs of Their Own Within 5 Years](https://www.yahoo.com/lifestyle/surgery-could-give-men-wombs-1302360099545142.html?soc_src=social-sh&soc_trk=tw11%2F17%2F15)**
>
> Hearing the news, we, and some of you, wondered: If science can transplant a uterus into a woman, can it transplant one into a man? Theoretically, men could receive a uterus, carry a baby to term,  and give birth. “My guess is five, 10 years...

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<div class="post-metadata">

**Author:** ![Leo\_Bloom](https://sea3.discourse-cdn.com/straightdope/user_avatar/boards.straightdope.com/leo_bloom/32/10377_2.png) [@Leo\_Bloom](https://boards.straightdope.com/u/Leo_Bloom)\
**Post date:** [November 18, 2015, 9:34pm UTC](https://boards.straightdope.com/t/could-the-placenta-continue-to-function/736909/136 "2015-11-18T21:34:41Z")

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> [@KarlGrenze](#):
>
> I deal with non-human placentas, and they look different. The majority of species do not have the discoid shaped deciduas…

You mean placenta shaped? (🙂 Hit the dictionaries/etymologies for that one.)

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**Author:** ![Emiliana](https://avatars.discourse-cdn.com/v4/letter/e/f0a364/32.png) [@Emiliana](https://boards.straightdope.com/u/Emiliana)\
**Post date:** [November 18, 2015, 10:12pm UTC](https://boards.straightdope.com/t/could-the-placenta-continue-to-function/736909/137 "2015-11-18T22:12:11Z")

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> [@WhyNot](#):
>
> I think this page is better than wikipedia. [The Placenta](http://www.sharinginhealth.ca/biology/placenta.html)
> 
> The fleshy red part that most people think of as “the placenta” is part of a part called _the decidua_. There are actually three parts even to that part. Everything that comes out of the mother before, during, and after birth, except for the baby, is all, collectively, “the placenta”, if you’re a scientist. The sacs, the umbilical cord, the amniotic liquid, the decidua…all parts of “the placenta”.
> 
> Most of us in this thread have been using the common meaning of _placenta_, referring to the decidua. But \*\*KarlGrenze \*\*is definitely correct.

Ignorance fought, even in a ludicrous thread such as this one.

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<div class="post-metadata">

**Author:** ![Nullpersona](https://avatars.discourse-cdn.com/v4/letter/n/b5ac83/32.png) [@Nullpersona](https://boards.straightdope.com/u/Nullpersona)\
**Post date:** [November 18, 2015, 11:54pm UTC](https://boards.straightdope.com/t/could-the-placenta-continue-to-function/736909/138 "2015-11-18T23:54:45Z")

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I stand corrected.

Since the chorion is the material for the vasculature to develop, and the amniotic sac provides the “landscaping cloth” I think of them as components of the larger fetal system, and the decidua as the placenta.

For clarity, I will refer to the decidua as such, from this point forward.

Whether or not the amniotic sac can be sustained, it’s contents and construction tell us what the non osmotic portion of the decidua requires. (including umbilicus)

The “maternal side of the placenta” tells us what environment is needed for the osmotic side of the decidua.

Providing similar environments after birth is not impossible.

To restate the original question:

Could the decidua continue to function?

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<div class="post-metadata">

**Author:** ![Oly](https://sea3.discourse-cdn.com/straightdope/user_avatar/boards.straightdope.com/oly/32/8255_2.png) [@Oly](https://boards.straightdope.com/u/Oly)\
**Post date:** [November 19, 2015, 1:40am UTC](https://boards.straightdope.com/t/could-the-placenta-continue-to-function/736909/139 "2015-11-19T01:40:58Z")

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What kind of response are you looking/hoping for?

If you are looking for a “no”, you have found many here.

If you are looking for a “yes”, you have found at least one here: Mine. (I’ve always been a sucker for kooky theoretically possible ideas. I take them in like other people do stray dogs.)

If you are looking for a “no” or a “yes” that is _backed up by evidence_, as in good experimental evidence from people who have actually tried to make it happen (which is, IMHO, what you really should be looking for if you are really serious about your enquiry) I humbly suggest that you are highly unlikely to find it here.

Got to [pubmed](http://www.ncbi.nlm.nih.gov/pubmed/?term=placenta). Scrounge around. It will be much more work than tossing out open ended questions and crafty metaphors\* in this forum, but, if your willing to do that work, you will get further long in your quest.

\*I’ve noticed your metaphors are often plant based. Do you have a background in farming, botany, horticulture, or something like that?

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<div class="post-metadata">

**Author:** ![KarlGrenze](https://avatars.discourse-cdn.com/v4/letter/k/dbc845/32.png) [@KarlGrenze](https://boards.straightdope.com/u/KarlGrenze)\
**Post date:** [November 19, 2015, 9:48am UTC](https://boards.straightdope.com/t/could-the-placenta-continue-to-function/736909/140 "2015-11-19T09:48:35Z")

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> [@Leo\_Bloom](#):
>
> You mean placenta shaped? (🙂 Hit the dictionaries/etymologies for that one.)

Flat disc? They all look pretty flat when deflated/emptied/after birth. 🙂

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