diphenhydramine hydrochloride = high ?

[MsRobyn]

*Originally posted by 5-HT *
**I’m sorry I don’t have a cite for this, but i seem to remember that Benadryl has anticholinergic effects and in high doses is hallucinogenic. This is not happy, fun LSD style hallucinations however. The first hand accounts of abuse I have heard generally sound very similar to fever hallucinations. Makes sense since many other anticholinergic substances are hallucinogenic(ie datura, jimson weed etc). So basically, yes, it can get you high, assuming you have a VERY wideranging definition of “high”. **

I just asked my dad about this (he’s a PharmD), and he said that Benadryl is slightly to moderately anticholinergic, but that if you take enough Benadryl to hallucinate, you’ll likely be dead first.

Robin