# Doctors and pharmacists:  Does codeine cause chills

**URL:** <https://boards.straightdope.com/t/doctors-and-pharmacists-does-codeine-cause-chills/159820>\
**Category:** Factual Questions\
**Created:** [March 8, 2003, 12:13am UTC](https://boards.straightdope.com/t/doctors-and-pharmacists-does-codeine-cause-chills/159820 "2003-03-08T00:13:21Z")\
**Posts on this page:** 7\
**Page:** 1

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**Author:** ![Spectre\_of\_Pithecanthropus](https://sea3.discourse-cdn.com/straightdope/user_avatar/boards.straightdope.com/spectre_of_pithecanthropus/32/12343_2.png) [@Spectre\_of\_Pithecanthropus](https://boards.straightdope.com/u/Spectre_of_Pithecanthropus)\
**Post date:** [March 8, 2003, 12:13am UTC](https://boards.straightdope.com/t/doctors-and-pharmacists-does-codeine-cause-chills/159820/1 "2003-03-08T00:13:21Z")

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…by slowing down circulation? I ask because I’m currently on it for postsurgical pain and I’m sitting in my house fully dressed with a terrycloth bathrobe over my clothes. I never do that ordinarily.

Or could that be from blood lost during the procedure? It was a septoplasty, so I not only lost blood during the surgery, but also when the doctor took out the padding today.

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**Author:** ![scout1222](https://avatars.discourse-cdn.com/v4/letter/s/34f0e0/32.png) [@scout1222](https://boards.straightdope.com/u/scout1222)\
**Post date:** [March 8, 2003, 12:30am UTC](https://boards.straightdope.com/t/doctors-and-pharmacists-does-codeine-cause-chills/159820/2 "2003-03-08T00:30:24Z")

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Warning! IANAD! But I did a Google search.

According to the site [www.drug-sideeffects.com](http://www.drug-sideeffects.com) the following are codeine side effects:

Codeine side effects include but are not limited to:

stomach bleeding  
kidney damage  
liver damage  
“itchies”  
constipation  
nausea  
hangover  
tiny pupils  
blurred vision  
poor night vision  
impair your ability to drive  
lowered heart rate, blood pressure and breathing  
disorientation  
convulsions  
hallucinations  
depression  
sexual problems  
agitation  
tremors  
seizures

Nothing on there about chills, but that doesn’t necessarily mean anything.

Any doctors care to chime in to help? Hope your surgery went okay and you’re healing quickly.

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**Author:** ![Qadgop\_the\_Mercotan](https://sea3.discourse-cdn.com/straightdope/user_avatar/boards.straightdope.com/qadgop_the_mercotan/32/83_2.png) [@Qadgop\_the\_Mercotan](https://boards.straightdope.com/u/Qadgop_the_Mercotan)\
**Post date:** [March 8, 2003, 12:56am UTC](https://boards.straightdope.com/t/doctors-and-pharmacists-does-codeine-cause-chills/159820/3 "2003-03-08T00:56:49Z")

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Lots of post-op patients have chills, related to fluid shifts, healing, possible infections, etc. etc. unrelated to opiates like codiene. I suppose the codiene could even contribute too. But it’s not a typical side-effect.

The best expert the OP could consult would be the surgeon who did the operation. You’re paying for that doctor’s advice.

QtM, MD

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**Author:** ![LouisB](https://avatars.discourse-cdn.com/v4/letter/l/dfb087/32.png) [@LouisB](https://boards.straightdope.com/u/LouisB)\
**Post date:** [March 8, 2003, 3:06am UTC](https://boards.straightdope.com/t/doctors-and-pharmacists-does-codeine-cause-chills/159820/4 "2003-03-08T03:06:02Z")

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I was treated for addiction to codeine. I abused that stuff for a long, long, time and I can attest to the accuracy of the above posted list of side effects. I don’t remember having chills, although there are lots of things I don’t remember from those years. I’m feeling much better now, though.

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**Author:** ![Squink](https://avatars.discourse-cdn.com/v4/letter/s/b5e925/32.png) [@Squink](https://boards.straightdope.com/u/Squink)\
**Post date:** [March 8, 2003, 4:24am UTC](https://boards.straightdope.com/t/doctors-and-pharmacists-does-codeine-cause-chills/159820/5 "2003-03-08T04:24:34Z")

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Morphine can have a hypothermic effect:

> [@](#):
>
> Action on thermogenesis. Morphine lowers the temperature of the normal animal. This action has been studied during habituation in the rabbit; the results obtained are contradictory.
> 
> While Girndt and Lipchitz (1931) find no habituation to thermal morphine reactions by chronic intoxication of the animal, Cahen (1935) notes a rise to more than one degree above normal in the temperature of the rabbit habituated to morphine for three months, and Ko (1937) points out that the hypothermy induced by morphine in the normal animal disappears with repeated injections of the drug.

[Here](http://www.unodc.org/odccp/bulletin/bulletin_1951-01-01_3_page005.html).  
[Many more](http://www.google.com/search?hl=en&lr=&ie=ISO-8859-1&safe=off&as_qdr=all&q=hypothermic+%22of+morphine%22).  
As QtM says, it’s typically not a problem. On the other hand, having remarkably large stents removed from ones nose while doped on codeine is a _very disturbing_ experience.

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**Author:** ![Spectre\_of\_Pithecanthropus](https://sea3.discourse-cdn.com/straightdope/user_avatar/boards.straightdope.com/spectre_of_pithecanthropus/32/12343_2.png) [@Spectre\_of\_Pithecanthropus](https://boards.straightdope.com/u/Spectre_of_Pithecanthropus)\
**Post date:** [March 8, 2003, 7:22pm UTC](https://boards.straightdope.com/t/doctors-and-pharmacists-does-codeine-cause-chills/159820/6 "2003-03-08T19:22:52Z")

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Thanks, all, for for your replies so far.

It occurred to me that opiates could have a chilling effect, and that might account for why many homeless people seem to be inappropriately bundled up in warm weather, if they’re addicts.

It was disturbing to have the packing taken out of my nose, let me tell you! As a matter of fact I delayed my next dose of painkiller so that I could take it just when I was leaving for the doctor’s office, and hopefully minimize the pain. It hurt, but the relief of getting those things out was stupendous.

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**Author:** ![Nametag](https://sea3.discourse-cdn.com/straightdope/user_avatar/boards.straightdope.com/nametag/32/406_2.png) [@Nametag](https://boards.straightdope.com/u/Nametag)\
**Post date:** [March 8, 2003, 8:07pm UTC](https://boards.straightdope.com/t/doctors-and-pharmacists-does-codeine-cause-chills/159820/7 "2003-03-08T20:07:35Z")

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Hey, I had a septoplasty this week, too! On the 4th. I was warned that chills could be a sign of infection (though normally when alternating with fever). Just being cold is most likely just the post-op thing, as QtM knows better than I.

For some reason I thought I’d be anaesthetized by the doctor, so I didn’t take a Vicodin before getting the packing out. Big mistake – I was crawling the walls by the time he finished, and then he had to take out the (what were they, splints?) enormous plastic disks, which didn’t look like they could ever have fit up my nose. And then there was the suction – I don’t want to think about the suction.

The homeless are bundled up for three reasons: (1) starving causes hypothermia, (2) it’s the only place some of them can carry their clothes, and (3) some of them are a little crazy.
