# Doctors/Pharmacist/Drugs Question

**URL:** <https://boards.straightdope.com/t/doctors-pharmacist-drugs-question/201044>\
**Category:** Factual Questions\
**Created:** [September 11, 2003, 9:09pm UTC](https://boards.straightdope.com/t/doctors-pharmacist-drugs-question/201044 "2003-09-11T21:09:08Z")\
**Posts on this page:** 2\
**Page:** 1

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**Author:** ![HighSoci](https://avatars.discourse-cdn.com/v4/letter/h/ba8739/32.png) [@HighSoci](https://boards.straightdope.com/u/HighSoci)\
**Post date:** [September 11, 2003, 9:09pm UTC](https://boards.straightdope.com/t/doctors-pharmacist-drugs-question/201044/1 "2003-09-11T21:09:08Z")

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Is it possible to OD on Zoloft or are all the remours of it being a placibo true? If so, how would it kill someone? Would it cause them to stop breathing? Make their heart explode? Or maybe just put them into a deep sleep to never wake again?

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**Author:** ![Sad\_Waters](https://avatars.discourse-cdn.com/v4/letter/s/898d66/32.png) [@Sad\_Waters](https://boards.straightdope.com/u/Sad_Waters)\
**Post date:** [September 11, 2003, 9:32pm UTC](https://boards.straightdope.com/t/doctors-pharmacist-drugs-question/201044/2 "2003-09-11T21:32:35Z")

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Zoloft and other SSRIs are relatively safe unlike their predecessors – Tricyclic antidepressants. That is one of the reasons why they are prescribed, patients are less likely to hurt themselves if they attempt to OD.

Most likely it would cause you to become very sleepy and nauseous.  
If you are really interested, you should go look it up in a PDR or call the Poison Center in your town.