Well, according to this there is some doubt that there is a scientific basis for this (unlike the anecdotal one that we have all heard and, frankly, I thought was fact):
I think that any sort of radical change in diet will give anyone gastric distress. I’ve seen this myself…if I suddenly eat a ton of, say, lobster with other rich foods I’ll be in a hell of a lot of distress. I imagine the same goes for someone used to eating Vegan or just vegetarian would have some distress from eating a large steak, since it’s very different than what they are used too. So, I think that the answer to the OP is probably ‘yes’, their digestive systems will react badly and they will probably spend some uncomfortable times on the toilet, but they will adjust fine in a short time…and ‘getting sick’, I’d guess, is probably more a psychological reaction except those who actually have meat based allergies. Getting the shits though…yeah, I think that’s likely. And not just for Vegans or vegetarian types making a change.
I agree with this part- whenever I go on vacation I have some sort of gastric issue and I have always attributed it mostly to my diet being different. But this “getting sick” that’s more than a psychological reaction- I’ve only ever heard vegans/vegetarians describe vomiting and/or a case of the runs when consuming animal products. Do people claim that they end up deathly ill or something?
I am on an intermittent fasting schedule that has me consuming only water for a 42 hour stretch three times a week. The first 3 or four times I broke my fast after this I experienced GI distress and diarrhea, but since then I have no issues.
My theory is that of the more than 1000 individual bacteria that form the gut biome there are some that require feeding more frequently than others. During the first few fasts these bacteria die off and are slowly replaced by ones that are more resistant to periods of fasting. By the time you’ve done this for a week or two natural selection has made your gut biome resistant to fasting.
It’s kind of funny, because people on fasting forums will adopt all kinds of special techniques to break their fast, but I’m convinced that time and time alone can eliminate the problem. What happens is they try something, and that doesn’t work, and they try something else, and that doesn’t work, and so on. When natural selection has solved their problem they swear that the cure was the last thing they tried, so you’ll see recommendations for chia seeds, bone broth, nuts, avocados, leafy greens, Greek yogurt, cooked vegetables, etc.; all of which people swear are effective.
Vegans may very well have had natural selection alter their gut biome, but in a few days or weeks I’m sure it can evolve to cope with meat.