# Emergency Help Needed. Cardiac Medicine Named \*Tardil\*

**URL:** https://boards.straightdope.com/t/emergency-help-needed-cardiac-medicine-named-tardil/91502
**Category:** Factual Questions
**Created:** [November 5, 2001, 12:55am UTC](https://boards.straightdope.com/t/emergency-help-needed-cardiac-medicine-named-tardil/91502 "2001-11-05T00:55:46Z")
**Posts on this page:** 8
**Page:** 1

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### Author: ![Zenster](https://avatars.discourse-cdn.com/v4/letter/z/cdc98d/32.png) [@Zenster](https://boards.straightdope.com/u/Zenster)
#### Post date: [November 5, 2001, 12:55am UTC](https://boards.straightdope.com/t/emergency-help-needed-cardiac-medicine-named-tardil/91502/1 "2001-11-05T00:55:46Z")

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Has anyone heard of this? It is a drug for heart conditions called “Tardil”.

I found a drug named Cardizem and another reference to Diltiazem, but my friend insists these are not the same. If anyone can please help me search for information I would be profoundly grateful.

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### Author: ![Zenster](https://avatars.discourse-cdn.com/v4/letter/z/cdc98d/32.png) [@Zenster](https://boards.straightdope.com/u/Zenster)
#### Post date: [November 5, 2001, 1:06am UTC](https://boards.straightdope.com/t/emergency-help-needed-cardiac-medicine-named-tardil/91502/2 "2001-11-05T01:06:51Z")

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This drug is being taken in conjunction with treatment for a coronary thrombosis. “Tardil” may be a foreign trade name for this compound. I have found this quote:

"Doctors sometimes prescribe Cardizem for loss of circulation in the fingers and toes (Raynaud’s Syndrome), for involuntary movements (tardive dyskinesia), and to prevent heart attack.

Tiazac and Dilacor XR are used in the treatment of high blood pressure and chronic stable angina. They may be taken alone or combined with other blood pressure medications."

This seems to indicate a strong relation to the patient’s condition as described to me. However it is insisted that this is not the drug in question. Ergo, I am hoping that anyone might have data on “Tardil”. It is being described to me as a “two phase sleeping drug”.

Again, any help would be deeply appreciated.

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### Author: ![GilaB](https://avatars.discourse-cdn.com/v4/letter/g/8e7dd6/32.png) [@GilaB](https://boards.straightdope.com/u/GilaB)
#### Post date: [November 5, 2001, 1:32am UTC](https://boards.straightdope.com/t/emergency-help-needed-cardiac-medicine-named-tardil/91502/3 "2001-11-05T01:32:42Z")

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> [@](#):
>
> \*Originally posted by Zenster \*  
> \*\*Has anyone heard of this? It is a drug for heart conditions called “Tardil”.
> 
> I found a drug named Cardizem and another reference to Diltiazem, but my friend insists these are not the same. If anyone can please help me search for information I would be profoundly grateful. \*\*

**IANAD** , but according to my 1999 edition of the Physician’s Desk Reference, diltiazem hydrochloride is the generic name of Cardizem, which is a drug for people with high blood pressure and angina (severe chest pain). I can’t find a listing for a drug named “Tardil”, but I don’t think that Cardizem can be it if you’re looking for a sleeping pill.

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### Author: ![Zenster](https://avatars.discourse-cdn.com/v4/letter/z/cdc98d/32.png) [@Zenster](https://boards.straightdope.com/u/Zenster)
#### Post date: [November 5, 2001, 1:35am UTC](https://boards.straightdope.com/t/emergency-help-needed-cardiac-medicine-named-tardil/91502/4 "2001-11-05T01:35:48Z")

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Thanks for responding, **GilaB**. Evidently Tardil is a trade name for a “two phase sleeping pill” made in Russia. I’ve been able to find a Russian pharmacological search engine, but I cannot read Cyrillic characters. Sigh!

Any Russian speaking people out there?

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### Author: ![MsRobyn](https://avatars.discourse-cdn.com/v4/letter/m/90ced4/32.png) [@MsRobyn](https://boards.straightdope.com/u/MsRobyn)
#### Post date: [November 5, 2001, 1:59am UTC](https://boards.straightdope.com/t/emergency-help-needed-cardiac-medicine-named-tardil/91502/5 "2001-11-05T01:59:46Z")

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Zenster, if you remind me via e-mail (available at the bottom of this post), I will be happy to look this up on Micromedex. It’s a HUGE database of virtually every known drug, but it’s a pay service, and I don’t have it at home.

Robin

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### Author: ![Zenster](https://avatars.discourse-cdn.com/v4/letter/z/cdc98d/32.png) [@Zenster](https://boards.straightdope.com/u/Zenster)
#### Post date: [November 5, 2001, 2:17am UTC](https://boards.straightdope.com/t/emergency-help-needed-cardiac-medicine-named-tardil/91502/6 "2001-11-05T02:17:43Z")

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Bless you, **MsRobyn**. (50% cooler than ordinary Robins!) You have my deepest gratitude.

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### Author: ![Zenster](https://avatars.discourse-cdn.com/v4/letter/z/cdc98d/32.png) [@Zenster](https://boards.straightdope.com/u/Zenster)
#### Post date: [November 6, 2001, 6:33am UTC](https://boards.straightdope.com/t/emergency-help-needed-cardiac-medicine-named-tardil/91502/7 "2001-11-06T06:33:42Z")

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> [@](#):
>
> \*Originally posted by FortMarcy \*  
> \*\*Is this info what you’re looking for? If not it might be a starting point:  
> [http://www.bda.bg/drugs/details/m2888d.htm](http://www.bda.bg/drugs/details/m2888d.htm)
> 
> > [@](#):
> >
> > 1 . Amobarbital - 125 mg  
> > 2 . Glutethimid - 125 mg  
> > 3 . Promethazine - 7 mg
> 
> \*\*

**MsRobyn** , if you see this before your email, please continue to work on this link. It appears to be the item in question. The manufacturer is Egis Pharmaceuticals, maybe out of Hungary. I’ll email this to you as well. Thanks for your help.

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### Author: ![astro](https://avatars.discourse-cdn.com/v4/letter/a/9dc877/32.png) [@astro](https://boards.straightdope.com/u/astro)
#### Post date: [November 6, 2001, 7:48am UTC](https://boards.straightdope.com/t/emergency-help-needed-cardiac-medicine-named-tardil/91502/8 "2001-11-06T07:48:35Z")

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from [http://chrom.tutms.tut.ac.jp/JINNO/DRUGDATA/00alphabet.html](http://chrom.tutms.tut.ac.jp/JINNO/DRUGDATA/00alphabet.html)

**Amobarbital**  
Physical Properties  
Molecular Formula : C11H 18N2O3  
Molecular weight : 226.28  
Chemical name : 5-ethyl-5-isopentylbarbituric acid  
properties : White crystal or crystalline powder. Non smell. Taste is slightly bitter.  
melting point : 156-159c  
pH : 5.0-6.0  
log P : 2.07 ( Experimentally determined value ) 2.11 ( Calculated value )  
Ionization Constant pKa : 7.8  
Solubility -Acetone, Ethanol , Ether : easily soluble  
Water , Chloroform : hardly soluble  
Oral administration / 1day : 100-300mg  
Drug Activity Classification : Hypnotic

**Glutethimid**  
Physical Properties  
Molecular Formula : C13H 15NO2  
Molecular weight : 217.27  
Chemical name : 2-ethyl-2-phenylglutarimide  
properties : White crystalline powder. Non smell. Taste is slightly bitter.  
melting point : 83-88c  
log P : 1.90 ( Experimentally determined value ) 1.89 ( Calculated value )  
Ionization Constant pKa : 9.2  
Solubility -Ethanol, Chloroform, Ether : easily soluble  
Water : hardly soluble  
Oral administration / 1day : 250-500mg  
Drug Activity Classification : Hypnotic

**Promethazine**  
Physical Properties  
Molecular Formula : C17H 20N2S  
Molecular weight : 284.42  
Chemical name : N-(2-dimethylamino-n-propyl)phenothiazine  
properties : powder. Non smell.  
log P : 4.65 ( Calculated value )  
Ionization Constant pKa : 9.1  
Oral administration / 1day : 25-200mg  
Drug Activity Classification : Antiparkinsonian
