# Enzyme based drain cleaners

**URL:** <https://boards.straightdope.com/t/enzyme-based-drain-cleaners/751931>\
**Category:** In My Humble Opinion\
**Created:** [April 11, 2016, 9:28pm UTC](https://boards.straightdope.com/t/enzyme-based-drain-cleaners/751931 "2016-04-11T21:28:06Z")\
**Posts on this page:** 2\
**Page:** 3

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**Author:** ![Do\_Not\_Taunt](https://sea3.discourse-cdn.com/straightdope/user_avatar/boards.straightdope.com/do_not_taunt/32/2968_2.png) [@Do\_Not\_Taunt](https://boards.straightdope.com/u/Do_Not_Taunt)\
**Post date:** [April 21, 2016, 5:28pm UTC](https://boards.straightdope.com/t/enzyme-based-drain-cleaners/751931/41 "2016-04-21T17:28:49Z")

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So the enzyme stuff never did anything for me. I ended up flushing a bunch of Drano down it, and sure enough, the clog cleared right away.

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**Author:** ![ci\_tech](https://avatars.discourse-cdn.com/v4/letter/c/e19b73/32.png) [@ci\_tech](https://boards.straightdope.com/u/ci_tech)\
**Post date:** [April 13, 2017, 6:10pm UTC](https://boards.straightdope.com/t/enzyme-based-drain-cleaners/751931/42 "2017-04-13T18:10:34Z")

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I followed the directions on the 2 pound bottle to a T, and all Thrift did was solidify. I took the extra step of first shop vac’ing all the water in the shower out first. I used boiling hot water to activate Thrift, but it did nothing. Has anyone had this happen to them?

Thank you in advance

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