# Fatal Fentanyl?

**URL:** <https://boards.straightdope.com/t/fatal-fentanyl/1014539>\
**Category:** Factual Questions\
**Created:** [February 19, 2025, 8:49pm UTC](https://boards.straightdope.com/t/fatal-fentanyl/1014539 "2025-02-19T20:49:56Z")\
**Posts on this page:** 3\
**Page:** 3

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**Author:** ![nearwildheaven](https://avatars.discourse-cdn.com/v4/letter/n/90db22/32.png) [@nearwildheaven](https://boards.straightdope.com/u/nearwildheaven)\
**Post date:** [February 21, 2025, 1:09am UTC](https://boards.straightdope.com/t/fatal-fentanyl/1014539/41 "2025-02-21T01:09:26Z")

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This new drug, suzetrigine, looks like a spinoff of anticonvulsants (lamotrigine has been on the market for many years) and we really are getting down to the molecular level, aren’t we?

(This is one reason why I am seriously thinking about putting my licenses on inactive status in 2026, something I always told myself I would never do.)

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**Author:** ![Wesley\_Clark](https://sea3.discourse-cdn.com/straightdope/user_avatar/boards.straightdope.com/wesley_clark/32/20581_2.png) [@Wesley\_Clark](https://boards.straightdope.com/u/Wesley_Clark)\
**Post date:** [February 21, 2025, 1:19am UTC](https://boards.straightdope.com/t/fatal-fentanyl/1014539/42 "2025-02-21T01:19:19Z")

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My understanding was there are 10 different sodium channels, and the 1.7 and 1.8 channels mostly control pain. This new drug selectively targets the 1.7 channel. I thought lamotrigine mostly worked by inhibiting the 1.4 sodium channel.

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**Author:** ![nearwildheaven](https://avatars.discourse-cdn.com/v4/letter/n/90db22/32.png) [@nearwildheaven](https://boards.straightdope.com/u/nearwildheaven)\
**Post date:** [February 21, 2025, 1:20am UTC](https://boards.straightdope.com/t/fatal-fentanyl/1014539/43 "2025-02-21T01:20:03Z")

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Nux vomica is actually the raw material for strychnine.

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