I’ve never had much luck trying to run screws into epoxy etc. if they had any kind of load on them at all. If it’s mostly cosmetic and the strain on the screw is modest, a glob of metal-compatible epoxy (usually gray/silver) in the hole, with the screw run in carefully as it’s mostly hardened, and then tape or some other support to hold the screw and trim in place until the epoxy sets… might work.