# Fresh fruit is...bad for you??? **URL:** \ **Category:** In My Humble Opinion\ **Created:** [July 16, 2004, 11:02pm UTC](https://boards.straightdope.com/t/fresh-fruit-is-bad-for-you/255504 "2004-07-16T23:02:45Z")\ **Posts on this page:** 4\ **Page:** 2
**Author:** ![Terminus\_Est](https://sea3.discourse-cdn.com/straightdope/user_avatar/boards.straightdope.com/terminus_est/32/3087_2.png) [@Terminus\_Est](https://boards.straightdope.com/u/Terminus_Est)\ **Post date:** [July 18, 2004, 4:49pm UTC](https://boards.straightdope.com/t/fresh-fruit-is-bad-for-you/255504/21 "2004-07-18T16:49:38Z")
It’s not that I disagree with you or your cites, **Epimetheus**. I am just skeptical that fructose [as you seemed to imply] is a significant factor in causing obesity over straight glucose. From your own cite [http://ific.org/publications/qa/fructoseqa.cfm](http://ific.org/publications/qa/fructoseqa.cfm) > [@](#): > > Some researchers have **speculated** that fructose may not be as satiating (produce feeling of fullness) as other carbohydrates because it does not stimulate insulin and leptin secretion nor suppress ghrelin production—all hormones that help to regulate hunger and food intake. However, preliminary research in this area has used **fructose levels that are at least three to four times higher than the average amount** consumed by Americans. [bolding mine] Here’s a counter-example that found no significant difference in weight-gain in monkeys fed with glucose, fructose, and sucralose [http://216.239.41.104/search?q=cache:FUcrN\_LKUggJ:wasc.ucdavis.edu/urc/Lindaposter.ppt+leptin+fructose&hl=en](http://216.239.41.104/search?q=cache:FUcrN_LKUggJ:wasc.ucdavis.edu/urc/Lindaposter.ppt+leptin+fructose&hl=en) > [@](#): > > Our goal was to see if a diet high in fructose would promote weight gain. As our plan of action rhesus monkeys were fed a diet high in fructose, glucose, or sucralose. After 34 weeks and with n=3 in each sugar group preliminary results showed no appreciable weight gain by the fructose fed monkeys. Glycolysis is generally the considered to be the first set of metabolic reactions the drives the energy-producing Krebs cycle and energy-storing lipogenesis (i.e. triglyceride production). It begins like this: ```auto Glucose --> glucose-6-P --> fructose-6-P --> [etc] --> acetyl-CoA ``` The last compound then enters the Krebs cycle or is used to form fatty acids. Fructose can enter the reaction by being directly converted to fructose-6-P, bypassing glucose altogether. Given the same amount of glucose and fructose, the latter can be converted into acetyl-CoA just a tiny bit faster. But fructose metabolism is only a single step shorter in an extremely long series of reactions. ---
**Author:** ![Ludovic](https://avatars.discourse-cdn.com/v4/letter/l/7ab992/32.png) [@Ludovic](https://boards.straightdope.com/u/Ludovic)\ **Post date:** [July 18, 2004, 7:31pm UTC](https://boards.straightdope.com/t/fresh-fruit-is-bad-for-you/255504/22 "2004-07-18T19:31:38Z")
Now, what if you had a refreshing beverage made out of many parts of a plant, so that you would be able to drink it on the go and still consume a lot of vitamins and fiber? For instance, orange juice, pulp, seeds… of course I didn’t say what _type_ of seeds… ---
**Author:** ![Epimetheus](https://avatars.discourse-cdn.com/v4/letter/e/c4cdca/32.png) [@Epimetheus](https://boards.straightdope.com/u/Epimetheus)\ **Post date:** [July 18, 2004, 8:59pm UTC](https://boards.straightdope.com/t/fresh-fruit-is-bad-for-you/255504/23 "2004-07-18T20:59:19Z")
> [@Terminus Est](#): > > It’s not that I disagree with you or your cites, **Epimetheus**. I am just skeptical that fructose [as you seemed to imply] is a significant factor in causing obesity over straight glucose. > > From your own cite [http://ific.org/publications/qa/fructoseqa.cfm](http://ific.org/publications/qa/fructoseqa.cfm) > > [bolding mine] I agree, it is not a definate thing and there is debate even amongst nutritionalists, I only offered a reason that the person in the OP would take fruit out of the menu and offer vegetables instead. The fact that there is controversy over fructose. I personally still eat plenty of fruit. ---
**Author:** ![mangeorge](https://avatars.discourse-cdn.com/v4/letter/m/d78d45/32.png) [@mangeorge](https://boards.straightdope.com/u/mangeorge)\ **Post date:** [July 18, 2004, 11:21pm UTC](https://boards.straightdope.com/t/fresh-fruit-is-bad-for-you/255504/24 "2004-07-18T23:21:07Z")
I used “curtail” in the OP in the “cut back” sense, not in the “stop completely” sense. 🙂 [Previous page](https://boards.straightdope.com/t/fresh-fruit-is-bad-for-you/255504.md?page=1)