For smallpox, we started vaccinations around 1798 and we achieved full eradication in 1980 - roughly 200 years later.
The problem isn’t so much in hitting the eradication rate of immunity, it’s hitting the eradication rate globally and staying consistent for a real, real long time. Since Covid spreads also in a wide variety of animals, that may be an even harder ask.
And it may seem like there would be no will to push to eradicate the disease once it becomes endemic but, I think, one strongly overlooked aspect of the pandemic is to realize that we’ve achieved the long impossible and cured the common cold.
Within society, between flu vaccines and the coming coronavirus vaccines, having to lie in bed coughing and sweating is going to become something that is largely optional. Some people, who would prefer to be disease free, are going to keep up on their immunations and successfully go years and decades without ever getting sick.
It is very possible that their success will lead others to follow and, eventually, you’ll have pockets of land where it’s a great travesty for someone to lie in bed coughing for a few days, and it will be giant news that it happened.
At that point in time, the push for global vaccination for the flu and the common cold will swell and we’ll finish the job.
To be sure, we’ll finish off polio and Dracunculiasis first. But, eventually, decades or centuries from now, Covid will get kicked off the cliff.
In the meanwhile, I’d stay focused on deciding whether you want to be on the leading edge of immunations or mentally segregate Covid from the common cold and the flu. Those do both kill people and have certainly killed more than Covid has, over the millennia. They’re going to keep on trying to do the same.