# I hate my body right now

**URL:** <https://boards.straightdope.com/t/i-hate-my-body-right-now/519411>\
**Category:** Factual Questions\
**Created:** [November 30, 2009, 1:31am UTC](https://boards.straightdope.com/t/i-hate-my-body-right-now/519411 "2009-11-30T01:31:02Z")\
**Posts on this page:** 3\
**Page:** 1

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**Author:** ![aruvqan](https://sea3.discourse-cdn.com/straightdope/user_avatar/boards.straightdope.com/aruvqan/32/2891_2.png) [@aruvqan](https://boards.straightdope.com/u/aruvqan)\
**Post date:** [November 30, 2009, 1:31am UTC](https://boards.straightdope.com/t/i-hate-my-body-right-now/519411/1 "2009-11-30T01:31:02Z")

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Not because I’m fat, and not because I am having joint issues, but because apparently I am either truely stupid, or a mutant. [don’t worry I am seeing my doc tomorrow morning anyway]

My doctor gave me clonidine in a patch form. Either somehow the sticky side of the patch does not have any medication on it, or I seem to not be able to absorb it through my skin.

I checked the instructions when I opened the box, it takes 3 days to get to where you have a theraputic level in your blood, so I call and confirm that I need to take my meds and taper off over the 3 days and I do so. it is now the 5th day, and since tapering off the damned pills, nada. It is as if I had absolutely nothing stuck to my arm. Does correct? Yup, same dose I was taking in pill form…

How can I NOT be absorbing something designed to absorb? I double checked, arm clean and dry? Yup. Sticky side on the arm? Yup. I wanted to take a shower and the edge was looking like it was coming up, so I used the cover patch that they helpfully included to keep it on the arm …

_sigh_

So, am i an idiot, or can people actually _not_ absorb stuff through the skin that is designed to go through?

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**Author:** ![running\_coach](https://sea3.discourse-cdn.com/straightdope/user_avatar/boards.straightdope.com/running_coach/32/15836_2.png) [@running\_coach](https://boards.straightdope.com/u/running_coach)\
**Post date:** [November 30, 2009, 1:49am UTC](https://boards.straightdope.com/t/i-hate-my-body-right-now/519411/2 "2009-11-30T01:49:12Z")

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From [here](http://www.rxlist.com/catapres-tts-drug.htm).

> [@](#):
>
> Proceeding from the visible surface towards the surface attached to the skin, there are four consecutive layers: 1) a backing layer of pigmented polyester and aluminum film; 2) a drug reservoir of clonidine, mineral oil, polyisobutylene, and colloidal silicon dioxide; 3) a microporous polypropylene membrane that controls the rate of delivery of clonidine from the system to the skin surface; 4) an adhesive formulation of clonidine, mineral oil, polyisobutylene, and colloidal silicon dioxide. **Prior to use, a protective slit release liner of polyester that covers the adhesive layer is removed**.

Did you do this?

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**Author:** ![aruvqan](https://sea3.discourse-cdn.com/straightdope/user_avatar/boards.straightdope.com/aruvqan/32/2891_2.png) [@aruvqan](https://boards.straightdope.com/u/aruvqan)\
**Post date:** [November 30, 2009, 4:23am UTC](https://boards.straightdope.com/t/i-hate-my-body-right-now/519411/3 "2009-11-30T04:23:39Z")

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> [@runner pat](#):
>
> From [here](http://www.rxlist.com/catapres-tts-drug.htm).
> 
> Prior to use, a protective slit release liner of polyester that covers the adhesive layer is removed.
> 
> Did you do this?

yup … wont stick unless you do [like peeling apart and sticking on a bandaid/sticking plaster]

We were so hoping that this would help - apparently I metabolize clonidine really rapidly, it tanks out on me in about 6 and a half hours or so rather than the 8 hours … and a 1 week patch would stop the sine wave action of my diastolic =(

I am wondering if it is because I do seem to metabolize clonidine so fast I just cant get the proper theraputic dose in my system and keep it there … _sigh_
