Well, at least they’re not owls puking in your bed.
I do hope I never have to experience that in my lifetime.
Dave Barry reference!
Well I’ve been studying cancer for almost 25 years and I’d be ok with it disappearing. 
We simplify extremely diverse ecosystems to monocultures and deserts. Maybe crop plants, and invasive weeds which colonize human-disturbed soils would die out. The insects which have found a niche in heated human homes would die out in colder areas. Probably dogs would die out, although their genes could live on in coyote and wolf hybrids. But there might be a couple hundred species we enable, compared to the millions that are threatened by us. Actually, we are threatening virtually all of them. It’s just not an argument at all.
Once when I was in the Midwest, we car camped at a small park which preserved about ten acres of original prairie. There must have been a thousand species packed into that ten acres, all packed together interacting with each other as they had for hundreds of thousands of years. I could hardly find two of the same plant in there. It was surrounded by corn fields with exactly one species in it. Square mile after square mile of corn. Not only the same species but genetically identical.
If I could have one wish it would be that mayonnaise disappeared from the world forever and could never be reinvented! Vile with no redeeming value.
All these people with their “special sauce” recipes that are just a delivery mechanism for the devil’s jizz can bite me.
Duplicates in the boxes of photos that I inherited from my mother, grandmother, and great-grandmother. Mostly I’m just not looking forward to the sorting. Partly I have way too many large copies of Mom’s high school graduation photo. As older relatives died, their children sent the signed copies back to her. Who does that?
But then what would I eat on my beans!?
Oh my lord, I hear you. When my aunt died it took 3 of us days to cull through all of her photos and half of that time was spent tossing dupes.
With older relatives, you also get postcards that were bought to commemorate vacations. They weren’t ever sent to anyone. They were just keepsakes, And they had already been passed down at least one generation.
But they weren’t labeled. There was no way to tell whose vacation they referred to. I still feel a little guilty when I think of tossing them. But once I gritted my teeth, they went fast.
That and the large number of just trees. We found several pics of ducks. No writing, no dates, no context - just ducks. That became our generic name for those types of pics. Solitary tree? ‘Duck’ picture. Random building? ‘Duck’ picture. Toss all duck pictures
while - of course - extinguished species would not magically re-appear … recall the huge number of wildlife sightings (pumas, condors, boars, foxes and whatnot) in cities during covid - just b/c fewer people were circulating …and cities became quieter.
now imagine the cities w/out population at all … they would def. buzz with wildlife within a year or so
So, I have the feeling a lot of species will “spring back” quite swiftly
Also, there never is a “given” number of fauna/flora (as sentences like “30% of the fauna of pleistocene went extinct” might imply) it is always an ongoing new ones come in, others go out forever … process or flow, rather than a status at a given time.
just like grassland burning off (and everything in it) … but coming back a year or 2 later to no long-term ill effect