I have always been able to do it. If I read aloud though I realise I am a bit slower reading upside down. Fortunately impressed observers don’t notice.
One of my favourite weird abilities stories was about a woman who could take dictation in either French or English and transcribe both the original and the translation simultaneously, French right handed and English left handed.
Not to mention less messy: a left handed writer in those days had a constant struggle with ink smears, if it had to write from left to right with ink that took an eternity to dry.
Here’s another vote for autism, especially its mild cousins, having an effect on latent ability to do this sort of thing. I’ve got compulsion to draw and sketch shapes, and spatial sense that gets me funny but appreciative looks when helping friends pack a moving van. I keep to myself, have certain tics (mild trichotillomania, strong reaction to loud sounds or persistent white noise, other OCD tics regarding pens and pencils) that mirror mild autism. All that said, I can’t remember not being able to read upside-down or backwards.
I suspect it has to do with the ability to seize a pattern from a scene and either (a) perform computation on it without rotating it internally, or (b) rotate it effortlessly and compute on the new image.
I also have a possibly related talent: being able to recognize animals in tall grass along a road while driving past at 70+ mph – a brown blur resolves to “woodchuck” or “fox” or “dead rabbit missing a leg” before nearly any of my passengers even sees it.
I have little trouble reading printed text upside-down. Handwriting is another story entirely. I really have to struggle to read handwritten (cursive) text upside-down, although with most people’s handwriting these days, it’s no picnic to read it rightside-up.
I think the reason it took so long to figure out Leonardo’s “code” is that it was backward cursive. Had it been printed, anyone would have quickly figured it out.
It’s important to note here that the ability to read easily at all, even for straight upright text, is far from universal. A great many people cannot parse text directly, but must rather sound out each word (perhaps silently, but still with lip movements or regulated breathing). Asimov once wrote of being bored on a subway, and reading upside-down the comic book another commuter was reading right-side-up. He grew impatient when the other rider took too long to turn the pages, and realized that she was shaping each word in her mouth.
Of course, the SDMB is very strongly selected for those who do read effortlessly, so it might be difficult to realize in a discussion here that this is not universal.
I don’t have a factual answer for the OP, but I do have an observation that might shed some light on things.
IME, when reading right-side-up text, three things seem to happen: 1.) the words are “heard” silently in my head; 2.) each word has a “feel” or “vibe” to it that helps tell it apart from similar words, and 3.) its meaning is instantly comprehended and integrated into the sentence being “heard” nonaurally. FWIW, #1 and #2 for me result in instant word-by-word recognition rather than sounding out of letters.
When reading upside down text, #2 doesn’t seem to be there at all. 1 and 3 must be relied upon exclusively to grasp the sentence being conveyed, which slows things down a bit. OTOH, wehn raeding scrmabled txet, the eyes glide effortlessly over the words but something about them “sticks out”.
Now this is only one person’s observation, but could it be that both brain hemispheres participate in the process, one being easily disrupted by poor spelling (left) and the other by rotation (right)?
Hmm… my ability is mixed, some word’s are easy such as book, I did stumble on Ideal thinking it was ‘learn’ and I thought ‘strength’ was ‘strategy’ I do have to concentrate more aswell.
The thesis of The Gift Of Dyslexia is that dyslexics have an enhanced spatial ability that includes processing 2D information (like letters on a page) in 3D - rotation about axes, mirroring etc. It is this additional processing that creates some of the symptoms of Dyslexia (reversed letters, d/b confusion), because from a spatial point of view, they are the same, just viewed from a different frame of reference.
Maybe dyslexics have a better ability to read upside-down because their brains can do the spatial mapping.