Depends on what you consider “big”. 
I like it, though.
Windows software:
Nero Burning ROM-burns anything. I’m not exaggerating.
Quake III
Winamp
Outlook Express
Mac software:
Microsoft Word 5.1-Why bother with newer versions if I don’t use the features? Plus, it’s stable.
MacLink Plus
Micronet Utility 7.5.1-This baby will format and partition anything. Screw the hacked version of HD SC Setup.
Netscape Navigator 4.77
StuffIt Expander 5.5
Disk Copy 6.3.3
Plus, I run all that on a PowerBook 540c: 33 Mhz 68040. I don’t need a PowerPC! 
And a quick mention goes to vi, my favorite UNIX text editor.