# LSD and Orange Juice

**URL:** <https://boards.straightdope.com/t/lsd-and-orange-juice/222137>\
**Category:** Factual Questions\
**Created:** [January 1, 2004, 5:08pm UTC](https://boards.straightdope.com/t/lsd-and-orange-juice/222137 "2004-01-01T17:08:27Z")\
**Posts on this page:** 5\
**Page:** 1

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**Author:** ![gypsymoth3](https://avatars.discourse-cdn.com/v4/letter/g/85e7bf/32.png) [@gypsymoth3](https://boards.straightdope.com/u/gypsymoth3)\
**Post date:** [January 1, 2004, 5:08pm UTC](https://boards.straightdope.com/t/lsd-and-orange-juice/222137/1 "2004-01-01T17:08:27Z")

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is it true that drinking orange juice will bring your trip back a little while after doing LSD? if so, how?

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**Author:** ![KidCharlemagne](https://avatars.discourse-cdn.com/v4/letter/k/ed8c4c/32.png) [@KidCharlemagne](https://boards.straightdope.com/u/KidCharlemagne)\
**Post date:** [January 1, 2004, 6:05pm UTC](https://boards.straightdope.com/t/lsd-and-orange-juice/222137/2 "2004-01-01T18:05:31Z")

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Vitamin C is the alleged active ingredient. In the 70’s, two doctors attempted to isolate compounds that would inhibit the effects of LSD and determined that vitamin C tended to decrease confusion and paranoia. I can’t attest to the legitimacy of the experiments and I don’t recall a proposed mechanism of pharmacologic action.

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**Author:** ![Johanna](https://sea3.discourse-cdn.com/straightdope/user_avatar/boards.straightdope.com/johanna/32/8318_2.png) [@Johanna](https://boards.straightdope.com/u/Johanna)\
**Post date:** [January 2, 2004, 12:16am UTC](https://boards.straightdope.com/t/lsd-and-orange-juice/222137/3 "2004-01-02T00:16:20Z")

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The folklore I heard years ago was niacin as the emergency vitamin dose if you needed to bring a trip down in a hurry. This seems to have been based on the idea that niacin causes the head to flush with blood, thus (supposedly) flushing the LSD molecules out of your brain. All I know is: a lot of niacin all at once makes your ears feel hot because of the sudden increased blood flow there.

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**Author:** ![alterego](https://avatars.discourse-cdn.com/v4/letter/a/6bbea6/32.png) [@alterego](https://boards.straightdope.com/u/alterego)\
**Post date:** [January 2, 2004, 1:53am UTC](https://boards.straightdope.com/t/lsd-and-orange-juice/222137/4 "2004-01-02T01:53:17Z")

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This is not simply with LSD. A search on Google will show you that grapefruit and orange juice have boosting effects on many prescription and illegal drugs.

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**Author:** ![II\_Gyan\_II](https://avatars.discourse-cdn.com/v4/letter/i/bbe5ce/32.png) [@II\_Gyan\_II](https://boards.straightdope.com/u/II_Gyan_II)\
**Post date:** [January 2, 2004, 1:59am UTC](https://boards.straightdope.com/t/lsd-and-orange-juice/222137/5 "2004-01-02T01:59:13Z")

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Niacin smoothens your trip (but **diminishes** the high). Chlorpromazine **aborts** the trip.