Teller was also a staunch advocate for the Strategic Defense Initiative (SDI), and particularly nuclear weapon powered X-ray and neutral particle directed energy weapons despite many technical objections to practicability that could not be mitigated by advancing the technology.
Lynn Margulis developed the now-widely accepted endosymbiotic theory (that eukaryotic organizisms with discrete organelles developed via symbiotic combination of separately evolved organisms) which underlies essentially of all modern molecular biology. She did this virtually single-handedly and in strong opposition by the established scientific consensus, for which she arguably should be due a Nobel Prize in Physiology or Medicine due to the value of the theory in understanding the role and dysfunction of mitochondria in cellular-level physiology. She went on, along with James Lovelock, to promote the so-called Gaia Hypothesis, that the entire planet is a single symbiotic organism that evolves via some kind of deliberate cooperative development, supposedly deprecting the role of natural selection to a minor factor in evolutionary development. Although the claim did bring additional attention to the wide scale interdependency to organisms and natural climate and hydrological systems in the overall biosystem, the idea that the entire planet is a single organism is oft-descried as “more hype than thesis” insofar as it doesn’t provide any falsifiable tests or a scientifically useable postulates.
Nikola Tesla is well known for his experiments with creation and conduction of electricity. In fact, the three-phase power transmission method employed today in every commerical and residential power grid in the world is based upon his system of alternating current, despite vigorous opposition by Edison. Tesla is almost as well known, however, for some of his more crackpot ideas and claims. While Tesla was a great experimentalist and integrator, his grasp on the actual physical principles of his experiements was often shaky.
Bruce medalist (and overlooked for a Nobel prize awarded to Fowler and Chandrasekshar) astronomer Fred Hoyle made great contributions to astrophysics and cosmology. However, he was noted for his staunch opposition to Big Bang theory long past the point that it was accepted by the astronomy community (due to the discovery of the cosmic microwave background and the cosmic redshift). He also argued against the (now widely accepted) chemical evolution of life, arguing (from no evidence whatsoever) that life began by pansporidia (from viruses falling from space). He made repeated claims that pulsars were signals from other civilizations well after it was widely theorized that they were in fact natural phenomena.
Kary B. Mullis, who was the 1993 Nobel Laureate for Chemistry for is invention of the polymerase chain reaction (PCR) which is used in most DNA matching tests and genome sequencing until recently. Mullis, however, has had a long history of bizarre and unfounded speculations, the most notorious of which is his claim that AIDS is not caused by the HIV virus. Although he has a small following on this issue, the vast majority of active researchers in the field of virology think he’s totally off his nut on this. In fact, most chemists regard his discovery/invention of PCR to be about the only viable thing he has ever produced in his career.
And as for Einstein: After a brief but fruitful period of innovation which turned the physics world upside down (or rather, without absolute reference whatsoever) he proceeded to blunder about, seeking a Theory of Everything for the next 30 years without success or conclusion. He considered his addition of a cosmological constant in GR to account for the expansion of the universe a big mistake, even though it now appears that there is in fact reason to believe that the “constant” is an appropriate correction.
Stranger