My wife probably has Multiple Sclerosis

My mother was mis-diagnosed with MS by a neurosurgeon who had not properly interpreted her MRI. At the time, it is needless to say, our family was absolutely torn apart by the original diagnosis, which my mother and father had no reason to doubt. If anything, my mom, who was a nurse and knew the doctor personally and professionally, probably gave his ruling more credence. But, on the off-chance that he was wrong, she got a second opinion, more out of wishful thinking than anything else. That doctor ordered a spinal tap (I don’t recall if they did the eye test as well), and reviewed the MRI, and eventually determined that she didn’t have MS.

She wound up having a totally benign brain tumor that she was most likely born with, it just had not been detected until then, which was what the first doctor was seeing on the MRI and mistaking for sclerosistic plaques. The physical symptoms were caused by previously undiagnosed case of mono–the tumor was entirely unrelated to them. These diagnoses were confirmed by subsequent MRIs over the last couple years (showing no growth or additional irregularities) and a positive test for Epstein-Barr.

I have no idea how common my mom’s experience is, but I would absolutely have your wife get the other tests.

Yesterday we got the results of the spinal tap - negative.

We both feel about thirty pounds lighter after that news, but the doctor did caution that MS is a ‘slow’ disease, and she has to go back in six months for a followup test.

It turns out spinal taps aren’t fun, especially if they require ten sticks to get spinal fluid successfully.

So thanks for asking.

Yipe - sorry to hear her spinal tap experience was not so good. The few times I’ve had lumbar punctures (not for a long time now), the doctor was very slick with the needle - no problems. Hopefully next time it will be less unpleasant.

As many above have noted, MS is a very personal experience.

I was diagnosed with MS in 1980 (I was 29). Back then, they didn’t do MRIs for MS diagnosis, so the initial diagnosis was made through examination of spinal fluid via a lumbar puncture. Conclusive testing via MRIs were then done sometime in the 1980s, and I have had MRIs pretty much yearly since 1996 or so.

From my experience, the critical element is getting a competent neurologist that you are comfortable with, who can interact efficiently with your primary care doctor. In the early 1990s, I had an absolute arrogant fool for a neurologist, who made it absolutely clear that he didn’t want to waste his time with me (since, at that time, I had minimal problems due to MS). I told my primary I was uncomfortable with him, and got another neuro within the medical group. The second neuro has been a godsend.

My current neuro has been ambivalent about most of the treatments currently available for MS (copaxon, interferons, etc), and is still taking a wait-and-see attitude with tysabri. I do have once-a-month infusions of solumedrol (essentially infusable prednisone), which has been (quality of) life-saving. Since starting the monthly solumedral regimen about three years ago, no additional lesions have shown up in my brain in the annual MRIs.

Even so, I get a major flare-up of MS-symptoms approximately every two years or so. The longest one lasted for about 13 weeks (about eight years ago), more frequently lasting three to six weeks. So far, I’ve pulled out of them with little degradation of quality of life, but even if the diagnosis is “relapsing-remitting” (as most of the MS diagnoses are), it is still generally a progressive disease.

If you have “paresthesia” (pins-and-needles feelings in your extremities), exercise can be difficult. I also have balance problems, so extended walking or running is not good (although I do use a treadmill at a gym where I can hold on if necessary). The best exercise I have found is swimming - it puts less strain on my legs.

Just to make life interesting, I was hit with a major case of shingles two years ago (on the trigeminal nerve on the face). It was great having a trusted neuro to deal with this - for some reason my HMO lets me make appointment with my neuro directly without having to go through my primary for each appointment - and I can usually get in to see him within a day or so of my calling for an appointment. I was told that although for most people, once they’ve had a shingles attack, they’re probably safe for the rest of their life, this is not true for people with MS; we can get a second attack of shingles. I guess this has to do with the overall weakening of the immune system.

I have to say though, this is one disease I would not want to have to deal with without gold-plated medical insurance. I can imagine how someone without very good insurance (or no insurance at all) could deal with it.
ETA: Looks like you hopefully won’t need any of my information.

I don’t know if this counts as a zombie or not, but here I am. Another MRI last week is consistent with MS, as well as her symptoms of weakness, pain, and distinct shortage of myelin in her brain.

In short, she has multiple sclerosis. So any advice or thoughts would be appreciated.

Like KatiRoo said, MS is a personal disease and affects people differently. I have two friends with MS and they’re different as night and day. One has managed to work full-time without much difficulty and the other can be laid low by an ordinary cold, and especially stress, physical or emotional. They both say that finding the right doctor has been really helpful to them. I don’t know what medications they’re taking, but they both pay a lot of attention to their diet – protein is important, apparently.

Good luck to your wife.

I’m sorry to hear that. I just read through the thread and it’s got to be tough to get this news after the results of the spinal tap were negative. A close friend of my family has had MS for 20 somethin’ years so I have some exposure to the disease. His condition has been relatively stable over the last 10 years and he’s now in his late fifties.

You and your wife have my best.

No advice, but I wanted to give you and your wife my best wishes.

Good luck.

Anyone with MS heard of Dr. Zamboni?

I’m also sorry to hear that. But take heart–there are lots of novel MS treatments coming down the pipe this year that look very promising. Most importantly…no injections!

http://www.businessweek.com/magazine/content/10_02/b4162053108084.htm

I’m sorry for your wife’s diagnosis. The good news is that many MS patients live a nearly symptom-free life, or at least have long periods of time with minor or no symptoms.

My sister-in-law was diagnosed with MS at 30. Unfortunately she has chroinc-progressive (“the bad kind”) which has gradually become progressively worse over the years. She’s 44 now and has been in a wheelchair for about 10 years.

I won’t go into a lot of details about her condition because she is truly at a far end of the scale in terms of debilitation and I don’t want to worry you. I would recommend looking into an MS support group in your area and if possible, find an doctor you trust who specializes in MS patients. Good luck to you both!

Yes, but I kind’a can’t remember where… :halo:

Jeez, that thread even references yet another Dr. Zamboni SDMB thread.

I’ll slink away now…

I have read of several studies with extremely promising results using stem cell transplants. The latest one was treating early-stage MS, at Northwestern University. Symptoms not only were halted, but reversed. Stem Cell Transplant Reverses Early-stage Multiple Sclerosis | ScienceDaily Previously, the studies I’d seen were for later stages.

I saw this as well and sent a copy of this to a family friend who has MS.

Both my father and father in law have MS. They were both diagnosed around the same age, but their paths have been very different. My dad was using a cane and was having moderate neurological issues within about 5 years of the diagnosis. My father in law was diagnosed 15 years ago, and while he does have an electronic walking assist (it sends electronic impulses to his foot that tell him to lift it up), he doesn’t have any canes or walkers, and his neurological impairments are minimal.

MS follows very different courses for different people. Even if this diagnosis is true, it’s not a death sentence. People can live with MS. My Dad is still going to walk me down the aisle at my wedding in 9 days, and he’ll dance with me at the reception. My father in law still plays guitar despite his MS causing minor motor skill impairment. He’ll be playing guitar at our reception.

She can still live a full life, even with MS.

This is helping - thank you.

The new work being done in MS is great, but I take it with huge grains of salt, and don’t tell my wife.

My MIL has had diabetes for 40 years, and for the 15 years I’ve known her, ‘scientists’ have been ‘this close’ to curing it. So it is, I imagine, with the MS research. It’s great that it’s being done and that some people are seeing amazing results, but I’m not holding my breath.