We still have not evolved beyond our hunter-gatherer bodies, we live in those bodies but our whole style of living (and eating) has changed. We no longer walk for our food and what’s what we were built to do. Weight problems should probably be in proportion to car ownership. What kind of overweight problems occur in those countries were the principle form of transportation is the bike? I’d bet it is low. And, of course, we live way longer than the hunter-gatherer, does the metabolic rate continue at the same rate in a 20 year old as it runs in a 60 year old?
Research being aimed at genetic treatment:
Enzyme could provide continual fat burning
Embargoed until 1 p.m. CST Thursday, March 29, 2001
HOUSTON–(March 29, 2001)–An enzyme discovered by Baylor College of Medicine researchers is critical to the metabolic pathway that governs the body’s ability to burn fat and could open a door into new ways to reduce obesity, diabetes and other fat-related human diseases.
In an article in the March 30 issue of the journal Science, Dr. Salih Wakil described laboratory mice, whose genes were manipulated to make them deficient in the enzyme acetyl-CoA carboxylase 2, or ACC2, as being able to eat as much as 40 percent more than normal mice and weigh 10 to 15 percent less. (jfoltin@bcm.tmc.edu in a press release embargoes until 1 p.m. CST Thursday, March 29, 2001)
And slight different:
Press release from: Eleanor Roosevelt Institute
Hormone the trigger for fat metabolism; scientists closer to tests in humans
DENVER – March 27, 2001 – Most people believe that obesity is only caused by eating too much or not getting enough exercise. But researchers from Denver’s Eleanor Roosevelt Institute have dramatic new evidence that implicates a low level of a certain hormone as an important factor in obesity.
[snip]
“Despite the perception in both the scientific community and the lay public that the only cause of obesity is either appetite or lack of exercise, this new study provides us with more information about how and why we do or do not store fat in our bodies.”
Published in the March 27 issue of the prestigious Proceedings of the National Academy of Sciences
[snip]
…Dr. Patterson said that this new understanding of weight control may also help people with cancer who often times experience dramatic and undesirable weight loss due to chemotherapy and radiation.
Dr. Brennan and his colleague Ute Hochgeschwender, Ph.D, of the Oklahoma Medical Research Foundation, originally discovered that the gene, POMC, was tied to fat metabolism. They published their findings in the international journal Nature Medicine in the fall of 1999.
I’m still betting on walking as the best way to take care of balancing out most of our body over weight problems.
Jois