Ok, so what's the straight dope on the whole "Splenda is practically DDT" crap?

It seems like I am always having to run a battery of experiments every time I’m working with a molecule with nitro groups or just several nitrogens. DSC, TSC, and RC1 mostly. And, of course, formation of N2 is the main driving force in several reactions, such as the Mitsonobu and AIBN as a radical initiator. By the way, I really, really hate DEAD.