# Paralysed man walks again after cell transplant

**URL:** <https://boards.straightdope.com/t/paralysed-man-walks-again-after-cell-transplant/702011>\
**Category:** Miscellaneous and Personal Stuff I Must Share\
**Created:** [October 21, 2014, 11:03am UTC](https://boards.straightdope.com/t/paralysed-man-walks-again-after-cell-transplant/702011 "2014-10-21T11:03:16Z")\
**Posts on this page:** 20\
**Page:** 1

<div class="post-metadata">

**Author:** ![Quartz](https://sea3.discourse-cdn.com/straightdope/user_avatar/boards.straightdope.com/quartz/32/267_2.png) [@Quartz](https://boards.straightdope.com/u/Quartz)\
**Post date:** [October 21, 2014, 11:03am UTC](https://boards.straightdope.com/t/paralysed-man-walks-again-after-cell-transplant/702011/1 "2014-10-21T11:03:16Z")

</div>

> **[Paralysed man walks again after cell transplant](https://www.bbc.co.uk/news/health-29645760)**
>
> A paralysed man becomes the first in the world to walk again following a pioneering therapy which involved transplanting cells from his nose into his severed spinal cord.

> [@](#):
>
> A paralysed man has been able to walk again after a pioneering therapy that involved transplanting cells from his nasal cavity into his spinal cord.

This is amazing news which could lead to a cure for many paralysed people.

---

<div class="post-metadata">

**Author:** ![GrandWino](https://sea3.discourse-cdn.com/straightdope/user_avatar/boards.straightdope.com/grandwino/32/67_2.png) [@GrandWino](https://boards.straightdope.com/u/GrandWino)\
**Post date:** [October 21, 2014, 3:30pm UTC](https://boards.straightdope.com/t/paralysed-man-walks-again-after-cell-transplant/702011/2 "2014-10-21T15:30:35Z")

</div>

[Story here.](http://www.independent.co.uk/life-style/health-and-families/health-news/british-doctors-on-brink-of-cure-for-paralysis-9807010.html)

Amazing time we’re living in.

> [@](#):
>
> Millions of paralysis sufferers are today offered the possibility of a cure for the first time after a new technique pioneered by British doctors allowed a man with a severed spinal cord to recover the ability to walk.
> 
> A revolutionary implant of regenerative cells has knitted back together the spinal cord of a wheelchair-bound firefighter paralysed from the chest down in a knife attack, restoring sensation and muscle control to his legs.
> 
> The astonishing breakthrough by an Anglo-Polish medical team is the first ever instance where a complete spinal paralysis has been reversed and represents the potential conquering of one of the greatest challenges in medical science. If validated, it offers hope of a life-changing therapy to the 2.5m people paralysed by spinal injury in Britain and across the world.
> 
> The technique, developed by researchers at University College London and put into practice by surgeons in the Polish city of Wroclaw, uses specialist human cells which repair damage to nasal nerves to enable spinal nerve fibres to re-grow and bridge a severed cord.

---

<div class="post-metadata">

**Author:** ![JKilez](https://avatars.discourse-cdn.com/v4/letter/j/e5b9ba/32.png) [@JKilez](https://boards.straightdope.com/u/JKilez)\
**Post date:** [October 21, 2014, 4:21pm UTC](https://boards.straightdope.com/t/paralysed-man-walks-again-after-cell-transplant/702011/3 "2014-10-21T16:21:35Z")

</div>

Wow, that is some amazing stuff. It looks like they have a ways to go before it is a “cure”, but it definitely shows potential.

---

<div class="post-metadata">

**Author:** ![Hypno-Toad](https://avatars.discourse-cdn.com/v4/letter/h/b2d939/32.png) [@Hypno-Toad](https://boards.straightdope.com/u/Hypno-Toad)\
**Post date:** [October 21, 2014, 6:43pm UTC](https://boards.straightdope.com/t/paralysed-man-walks-again-after-cell-transplant/702011/4 "2014-10-21T18:43:36Z")

</div>

I wonder if they’ll be able one day to recreate the effect of the olfactory regeneration in other nerve cells and so preclude the need for transplantation.

---

<div class="post-metadata">

**Author:** ![Smeghead](https://avatars.discourse-cdn.com/v4/letter/s/f1d935/32.png) [@Smeghead](https://boards.straightdope.com/u/Smeghead)\
**Post date:** [October 21, 2014, 6:48pm UTC](https://boards.straightdope.com/t/paralysed-man-walks-again-after-cell-transplant/702011/5 "2014-10-21T18:48:32Z")

</div>

Huh. I saw a documentary about a decade ago where they were doing this exact thing as a preliminary trial.

---

<div class="post-metadata">

**Author:** ![cmyk](https://sea3.discourse-cdn.com/straightdope/user_avatar/boards.straightdope.com/cmyk/32/3353_2.png) [@cmyk](https://boards.straightdope.com/u/cmyk)\
**Post date:** [October 21, 2014, 7:29pm UTC](https://boards.straightdope.com/t/paralysed-man-walks-again-after-cell-transplant/702011/6 "2014-10-21T19:29:43Z")

</div>

Now, if only they can restore his sense of smell!

But really, that’s a remarkable breakthrough for spinal cord injuries (and I’m guessing other similar nervous system injuries).

---

<div class="post-metadata">

**Author:** ![Oukile](https://avatars.discourse-cdn.com/v4/letter/o/13edae/32.png) [@Oukile](https://boards.straightdope.com/u/Oukile)\
**Post date:** [October 21, 2014, 8:28pm UTC](https://boards.straightdope.com/t/paralysed-man-walks-again-after-cell-transplant/702011/7 "2014-10-21T20:28:47Z")

</div>

Yes, and while we are at it: another approach based on electrical stimulation of the spinal cord:

[http://www.reevebigidea.org/the-research](http://www.reevebigidea.org/the-research)

I have some close colleagues working in this field. We are nowhere near ‘walking again normally’: these people walk in a lab with robotic assistance. But the field is getting closer to clinical trials with serious hope for improvements in lower body function and therefore quality of life.

---

<div class="post-metadata">

**Author:** ![Alessan](https://sea3.discourse-cdn.com/straightdope/user_avatar/boards.straightdope.com/alessan/32/465_2.png) [@Alessan](https://boards.straightdope.com/u/Alessan)\
**Post date:** [October 21, 2014, 8:57pm UTC](https://boards.straightdope.com/t/paralysed-man-walks-again-after-cell-transplant/702011/8 "2014-10-21T20:57:31Z")

</div>

My little brother has a C6 spinal injury from a hiking accident eight years ago. It left him with limited arm movement and almost nothing else from the neck down.

I’m following this very closely.

---

<div class="post-metadata">

**Author:** ![Amateur\_Barbarian](https://avatars.discourse-cdn.com/v4/letter/a/59ef9b/32.png) [@Amateur\_Barbarian](https://boards.straightdope.com/u/Amateur_Barbarian)\
**Post date:** [October 21, 2014, 9:01pm UTC](https://boards.straightdope.com/t/paralysed-man-walks-again-after-cell-transplant/702011/9 "2014-10-21T21:01:45Z")

</div>

Christopher Reeve always believed he’d live long enough to see this happen.

---

<div class="post-metadata">

**Author:** ![GrandWino](https://sea3.discourse-cdn.com/straightdope/user_avatar/boards.straightdope.com/grandwino/32/67_2.png) [@GrandWino](https://boards.straightdope.com/u/GrandWino)\
**Post date:** [October 21, 2014, 9:12pm UTC](https://boards.straightdope.com/t/paralysed-man-walks-again-after-cell-transplant/702011/10 "2014-10-21T21:12:33Z")

</div>

There is another thread on the topic started earlier than mine and I’ve reported this and asked it to be closed/merged. Just fyi.

---

<div class="post-metadata">

**Author:** ![twickster](https://avatars.discourse-cdn.com/v4/letter/t/ec9cab/32.png) [@twickster](https://boards.straightdope.com/u/twickster)\
**Post date:** [October 21, 2014, 9:14pm UTC](https://boards.straightdope.com/t/paralysed-man-walks-again-after-cell-transplant/702011/11 "2014-10-21T21:14:12Z")

</div>

Merged duplicate threads.

---

<div class="post-metadata">

**Author:** ![Ambivalid](https://avatars.discourse-cdn.com/v4/letter/a/a5b964/32.png) [@Ambivalid](https://boards.straightdope.com/u/Ambivalid)\
**Post date:** [October 21, 2014, 10:01pm UTC](https://boards.straightdope.com/t/paralysed-man-walks-again-after-cell-transplant/702011/12 "2014-10-21T22:01:11Z")

</div>

This is awesome news and hopefully will be the breakthrough it promises to be. However, what it will not be is any kind of boon for the millions of people who have been paralyzed for years or decades and whose bodies have atrophied and wasted away to the point that bone loss, muscle and soft tissue loss and other degenerative problems would make walking again-even if a cure ever came about-simply impossible.

---

<div class="post-metadata">

**Author:** ![Mr.Nylock](https://avatars.discourse-cdn.com/v4/letter/m/77aa72/32.png) [@Mr.Nylock](https://boards.straightdope.com/u/Mr.Nylock)\
**Post date:** [October 21, 2014, 10:14pm UTC](https://boards.straightdope.com/t/paralysed-man-walks-again-after-cell-transplant/702011/13 "2014-10-21T22:14:23Z")

</div>

> [@Ambivalid](#):
>
> This is awesome news and hopefully will be the breakthrough it promises to be. However, what it will not be is any kind of boon for the millions of people who have been paralyzed for years or decades and whose bodies have atrophied and wasted away to the point that bone loss, muscle and soft tissue loss and other degenerative problems would make walking again-even if a cure ever came about-simply impossible.

Why wouldn’t steroids or human growth hormone be able to help with that? Maybe that’s just a dumb question, I know next to nothing about medicine.

---

<div class="post-metadata">

**Author:** ![Ambivalid](https://avatars.discourse-cdn.com/v4/letter/a/a5b964/32.png) [@Ambivalid](https://boards.straightdope.com/u/Ambivalid)\
**Post date:** [October 21, 2014, 10:59pm UTC](https://boards.straightdope.com/t/paralysed-man-walks-again-after-cell-transplant/702011/14 "2014-10-21T22:59:52Z")

</div>

> [@Mr.Nylock](#):
>
> Why wouldn’t steroids or human growth hormone be able to help with that? Maybe that’s just a dumb question, I know next to nothing about medicine.

The bones of a paralyzed person, after decades of no use, become extremely brittle, light and weak; basically osteoporotic. Severely. Breaks and fractures can and do often occur from small, everyday movements such as transferring from the wheelchair to the toilet. Also, in addition to the muscle atrophy, which for people with flaccid paralysis who experience no spasticity can be **startlingly** severe, the muscles will actually shorten, or contract. This means many people with spinal cord injuries cannot actually even straighten their legs fully, or even close to fully, because the hamstring muscles are so tight and atrophied. The devastation to the human body after decades of living with spinal cord injury is truly profound. There really is no getting back what was lost after a certain point of living as a para/quadriplegic.

Even if, after years of grueling and painful, exhaustive physical therapy and groundbreaking medical treatment, a long-injured person is made able to ambulate again, it would be a night and day difference from what they were like prior to their injury. It wouldn’t be “walking” in the sense that most people know the term.

---

<div class="post-metadata">

**Author:** ![Ambivalid](https://avatars.discourse-cdn.com/v4/letter/a/a5b964/32.png) [@Ambivalid](https://boards.straightdope.com/u/Ambivalid)\
**Post date:** [October 21, 2014, 11:09pm UTC](https://boards.straightdope.com/t/paralysed-man-walks-again-after-cell-transplant/702011/15 "2014-10-21T23:09:04Z")

</div>

> [@Ambivalid](#):
>
> Even if, after years of grueling and painful, exhaustive physical therapy and groundbreaking medical treatment, a long-injured person is made able to ambulate again, it would be a night and day difference from what they were like prior to their injury. It wouldn’t be “walking” in the sense that most people know the term.

And this is the main reason why, for a large number of paralyzed people (myself included), such a “cure” would hold no interest to them. They are happy with their lives as is and don’t feel that they are even in need of any “cure” in the first place. This is the life they know now and the idea of spending years and going thru all that pain, basically stopping the life they know, just so they can “walk” in some unsightly, inefficient, horribly unstable manner just is not a desirable future. It can become a bit offensive at times when the world is constantly telling you you are in need of being fixed. That you are broken. I’ve spent the past 14 understanding and realizing just the opposite.

---

<div class="post-metadata">

**Author:** ![Cat\_Whisperer](https://sea3.discourse-cdn.com/straightdope/user_avatar/boards.straightdope.com/cat_whisperer/32/4839_2.png) [@Cat\_Whisperer](https://boards.straightdope.com/u/Cat_Whisperer)\
**Post date:** [October 22, 2014, 12:48am UTC](https://boards.straightdope.com/t/paralysed-man-walks-again-after-cell-transplant/702011/16 "2014-10-22T00:48:42Z")

</div>

I love reading stories like this, where science seems to make a huge leap forward. I understand that it isn’t a cure, it isn’t for everyone, and it has a long way to go yet, but man, what a world we live in! Moar research! I want my tooth transplants and my flying car!

---

<div class="post-metadata">

**Author:** ![Quartz](https://sea3.discourse-cdn.com/straightdope/user_avatar/boards.straightdope.com/quartz/32/267_2.png) [@Quartz](https://boards.straightdope.com/u/Quartz)\
**Post date:** [October 22, 2014, 11:29am UTC](https://boards.straightdope.com/t/paralysed-man-walks-again-after-cell-transplant/702011/17 "2014-10-22T11:29:26Z")

</div>

> [@Ambivalid](#):
>
> There really is no getting back what was lost after a certain point of living as a para/quadriplegic.

This is very much a first and I’m hoping you’re very wrong.

---

<div class="post-metadata">

**Author:** ![Alessan](https://sea3.discourse-cdn.com/straightdope/user_avatar/boards.straightdope.com/alessan/32/465_2.png) [@Alessan](https://boards.straightdope.com/u/Alessan)\
**Post date:** [October 22, 2014, 11:53am UTC](https://boards.straightdope.com/t/paralysed-man-walks-again-after-cell-transplant/702011/18 "2014-10-22T11:53:31Z")

</div>

Giving someone the ability to do something - anything - they couldn’t do before is never wrong.

---

<div class="post-metadata">

**Author:** ![Smeghead](https://avatars.discourse-cdn.com/v4/letter/s/f1d935/32.png) [@Smeghead](https://boards.straightdope.com/u/Smeghead)\
**Post date:** [October 22, 2014, 2:07pm UTC](https://boards.straightdope.com/t/paralysed-man-walks-again-after-cell-transplant/702011/19 "2014-10-22T14:07:27Z")

</div>

And, of course, even if Ambivalid is right and the atrophy proves to be irreversible, this still provides tremendous hope for people who are paralyzed in the future. If this treatment works out, future patients could be treated before the atrophy begins.

---

<div class="post-metadata">

**Author:** ![Ambivalid](https://avatars.discourse-cdn.com/v4/letter/a/a5b964/32.png) [@Ambivalid](https://boards.straightdope.com/u/Ambivalid)\
**Post date:** [October 22, 2014, 3:26pm UTC](https://boards.straightdope.com/t/paralysed-man-walks-again-after-cell-transplant/702011/20 "2014-10-22T15:26:20Z")

</div>

> [@Smeghead](#):
>
> And, of course, even if Ambivalid is right and the atrophy proves to be irreversible, this still provides tremendous hope for people who are paralyzed in the future. If this treatment works out, future patients could be treated before the atrophy begins.

Absolutely.

[Next page](https://boards.straightdope.com/t/paralysed-man-walks-again-after-cell-transplant/702011.md?page=2)
