# Quick question about hydroxychloroquine

**URL:** <https://boards.straightdope.com/t/quick-question-about-hydroxychloroquine/916731>\
**Category:** The Quarantine Zone\
**Tags:** covid-quarantine\
**Created:** [July 29, 2020, 5:04pm UTC](https://boards.straightdope.com/t/quick-question-about-hydroxychloroquine/916731 "2020-07-29T17:04:36Z")\
**Posts on this page:** 6\
**Page:** 2

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**Author:** ![Omar\_Little](https://sea3.discourse-cdn.com/straightdope/user_avatar/boards.straightdope.com/omar_little/32/269_2.png) [@Omar\_Little](https://boards.straightdope.com/u/Omar_Little)\
**Post date:** [August 6, 2020, 6:05pm UTC](https://boards.straightdope.com/t/quick-question-about-hydroxychloroquine/916731/21 "2020-08-06T18:05:43Z")

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> [@Ann\_Hedonia](#):
>
> They make almost ZERO case for the use of Hydroxychloroquine as a COVID cure, in fact neither of your cites even mention Hydroxychloroquine.

You need to read more closely. I was not posting in defense of hydroxychlorquine. I know this topic is a political trigger for some. I was making the point that many physicians that have used the drug are using it for it’s blood thinning capabilities, which are not in dispute. Although there are better blood thinners on the market than this particular drug. The articles I posted were about the effects that clotting and clots are primary condition of those with severe cases of COVID.

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**Author:** ![DMC](https://sea3.discourse-cdn.com/straightdope/user_avatar/boards.straightdope.com/dmc/32/18049_2.png) [@DMC](https://boards.straightdope.com/u/DMC)\
**Post date:** [August 6, 2020, 10:37pm UTC](https://boards.straightdope.com/t/quick-question-about-hydroxychloroquine/916731/22 "2020-08-06T22:37:31Z")

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> [@Snowboarder\_Bo](#):
>
> There are a number of rebuttals to Dr. Risch’s paper; they are linked on the right hand side of the page under the heading “More On This Topic”

My favorite rebuttal is from his colleagues, who actually associate him with Peter Duesberg (yes, he of the belief that AIDS was not caused by HIV, and ended up being at least partially responsible for hundreds of thousands of deaths) in their strongly worded rebuttal.

[https://medium.com/@gregggonsalves/statement-from-yale-faculty-on-hydroxychloroquine-and-its-use-in-covid-19-47d0dee7b2b0](https://medium.com/@gregggonsalves/statement-from-yale-faculty-on-hydroxychloroquine-and-its-use-in-covid-19-47d0dee7b2b0)

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**Author:** ![Snowboarder\_Bo](https://sea3.discourse-cdn.com/straightdope/user_avatar/boards.straightdope.com/snowboarder_bo/32/229_2.png) [@Snowboarder\_Bo](https://boards.straightdope.com/u/Snowboarder_Bo)\
**Post date:** [August 6, 2020, 11:27pm UTC](https://boards.straightdope.com/t/quick-question-about-hydroxychloroquine/916731/23 "2020-08-06T23:27:25Z")

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Excellent!

For those that don’t want to read the entire letter, the conclusion sums it all up nicely:

> [@](#):
>
> While minority opinions, anecdotal evidence, novel interpretations and challenges to orthodoxies in a field can be important, at some point, the application of the scientific method generating evidence from multiple, well-designed clinical trials and observational studies does matter and should be heard over the noise of conspiracy theories, purported hoaxes, and the views of zealots.

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**Author:** ![Tfletch1](https://sea3.discourse-cdn.com/straightdope/user_avatar/boards.straightdope.com/tfletch1/32/5340_2.png) [@Tfletch1](https://boards.straightdope.com/u/Tfletch1)\
**Post date:** [August 7, 2020, 3:24am UTC](https://boards.straightdope.com/t/quick-question-about-hydroxychloroquine/916731/24 "2020-08-07T03:24:30Z")

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> [@Omar\_Little](#):
>
> One of the effects of hydroxychloroquine found by some doctors are it anti-inflammatory properties and inhibiting platelet clumping and blood clots. There have been several studies that have found in severe cases of COVID-19, that the protein von Willebrands factor is increased in the bloodstream which promotes clotting. It is this clotting in the lungs which is one of the fatal factors of COVID19. It is a standard protocol now to give patients in the ICU with COVID19 blood thinners to fight off this increased clotting brought on by the virus.

Cites needed for this whole paragraph.

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**Author:** ![DrDeth](https://avatars.discourse-cdn.com/v4/letter/d/b487fb/32.png) [@DrDeth](https://boards.straightdope.com/u/DrDeth)\
**Post date:** [August 16, 2020, 9:42pm UTC](https://boards.straightdope.com/t/quick-question-about-hydroxychloroquine/916731/25 "2020-08-16T21:42:49Z")

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why? It is well known that the drug helps with certain symptoms. So does aspirin. That doesn’t make either one a cure or a preventative.

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**Author:** ![Tfletch1](https://sea3.discourse-cdn.com/straightdope/user_avatar/boards.straightdope.com/tfletch1/32/5340_2.png) [@Tfletch1](https://boards.straightdope.com/u/Tfletch1)\
**Post date:** [August 16, 2020, 10:19pm UTC](https://boards.straightdope.com/t/quick-question-about-hydroxychloroquine/916731/26 "2020-08-16T22:19:58Z")

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Are you addressing me? It is not well known that hydroxychloroquine helps with certain symptoms. Regardless, Omar Little is making very specific claims. For example, von Willebrand’s factor is part of the clotting cascade and there is such thing as covid-19 associated coagulopathy. I don’t know of any studies to show that they are linked and would like to see them. It would be interesting. In addition, I would like like to see a study that links hydroxychloroquine to von Willebrand’s factor or anything in the clotting cascade. I was under the impression that its mode of action is through processing of autoantigens and T cell hyperactivity.

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