Sherlock Holmes quote meaning

This, clearly.

No problem. Thanks for the correction. I haven’t read the story in at least 20 years.

Actually, he was quite fit and energetic, even when not on a cocaine bender. Quite the boxer as I recall.

The “secondary effects” of cocaine usage may have been a description of the fits of extreme lassitude affecting him between cocaine highs.

Freud had a lot of trouble with the downside of cocaine use.

Yes. Moment as in momentous (the opposite of momentous would be ‘of small moment’)