# The Least Fun Thing Ever. Advice? **URL:** \ **Category:** Miscellaneous and Personal Stuff I Must Share\ **Created:** [October 13, 2002, 2:57am UTC](https://boards.straightdope.com/t/the-least-fun-thing-ever-advice/132038 "2002-10-13T02:57:44Z")\ **Posts on this page:** 2\ **Page:** 1
**Author:** ![dinahmoe](https://avatars.discourse-cdn.com/v4/letter/d/8797f3/32.png) [@dinahmoe](https://boards.straightdope.com/u/dinahmoe)\ **Post date:** [October 13, 2002, 2:57am UTC](https://boards.straightdope.com/t/the-least-fun-thing-ever-advice/132038/1 "2002-10-13T02:57:44Z")
For the past year, I have been having this odd condition in my lower left leg. It consists of very painful raised nodules, and an extremely swollen ankle joint. I am 32 years old, female, and before this happened, an active snowboarder, rollerblader, hiker…etc. I have been to 5 different doctors, and had biopsies, physical therapy, steroids, and countless other treatments. Two weeks ago, a rhumetologist at Brigham & Women’s declared that he had seen just 3 other cases like mine, there was no name for it, and the best treatment for it is a drug called Methotrexate. Methotrexate is a chemotherapy drug, used for certain cancers, and rhumetiod arthritis. I started taking it this morning. Suck-diddly-uks. I am nauseated, and have a weird slimy/metallic thang going on in my mouth. Barfing has become a hobby. Has anyone had any experience with this drug? Is it gonna get worse? Better? Can I keep my hair? What’s the best way to combat tummy upset? Help? ---
**Author:** ![misstee](https://avatars.discourse-cdn.com/v4/letter/m/958977/32.png) [@misstee](https://boards.straightdope.com/u/misstee)\ **Post date:** [October 13, 2002, 5:03am UTC](https://boards.straightdope.com/t/the-least-fun-thing-ever-advice/132038/2 "2002-10-13T05:03:37Z")
My mom takes that-- she hasn’t had the best expierence with it, either. How long have you been taking it? I can ask her what they told her the side effects would be. I am sorry that you feel so ill.