Tylenol does not cause liver disease, Tylenol can cause liver damage. Keep your dose under 4 grams a day (3 grams if you’re in a high risk group) and ask your doctor to check your liver enzymes regularly if you take it regularly. Don’t take it after drinking alcohol to excess, and don’t take other medications, including over the counter cold and sinus remedies that have acetaminophen in them.
I absolutely believe you that Tylenol doesn’t help you, personally. People are all different in their reactions to medications, and Tylenol doesn’t provide relief for everyone; that’s why it’s a good thing that we have so many options after that one.
I am positively gobsmacked that you would imply that Morphine should be used as a *first *line pharmacologic intervention for mild to moderate OA, however. That’s not good for patients in the long term, with a very high risk of dependence and growing tolerance that leads to an extremely narrow therapeutic window before respiratory depression sets in.