Tylenol w/ codeine or hydrocodone, but not aspirin?

[neutron_star]

@M. Meursault

On the contrary: meet the aptly named Vicoprofen

Interesting. Thank you.

I wonder why nobody I’ve ever known has been prescribed the stuff. It seems like it would be a more effective pain reliever than the alternatives (unless opiates somehow potentiate the effects of asprin and acetaminophen, but not ibuprofen).

[chorpler]

@neutron star

Interesting. Thank you.

I wonder why nobody I’ve ever known has been prescribed the stuff. It seems like it would be a more effective pain reliever than the alternatives (unless opiates somehow potentiate the effects of asprin and acetaminophen, but not ibuprofen).

… which has not been my experience. I’m only one data point, of course, but I always found ibuprofen to be a lot more effective with codeine or hydrocodone than acetaminophen was. (I never tried aspirin, so I can’t comment on that.)

[R.P.McMurphy]

@M. Meursault

On the contrary: meet the aptly named Vicoprofen

As was noted, acetaminophen w/codeine is available OTC in Canada. However, unless it has changed recently, codeine w/ ibuprofen is not. Is there a reason?

[Thudlow_Boink]

@Qadgop the Mercotan

It’s mildly accurate. One can die of aspirin toxicity, but it is easier to die of acetaminophen toxicity. And usually without the warning symptoms that come with aspirin toxicity

For what it’s worth, here’s a link to Cecil’s column on the dangers on Tylenol.

[vetbridge]

@MyNameIsEarl

Isn’t it easier to do cold-extraction from acetaminophen than aspirin though? In other words, isn’t it easier to separate the codeine from acetaminophen than aspirin? I mean, anyone with five minutes, and Internet connection and a coffee filter can do that.

Yep. I guess the idea is that not many people have that information. Until now.

[elfbabe]

@ftg

Umm, note the phrasing in the commercials: “plus an extra ingredient that may relieve pain.” Note the “may”. Consumer Reports and similar groups don’t know of any analgesic benefit of caffiene other than some people (but not all) like the extra buzz it gives them.

If they had proof, they’d drop the “may”. (It’s also funny that after all these decades they never bothered to do their own study about their own claims. Hmmm.)

Actually, caffeine does a DAMN good job of curing a headache… provided it’s a headache caused by caffeine withdrawal.

[edwino]

BTW,

Synalgos-DC = aspirin/caffeine/dihydrocodeine
Darvon Compound-32 and -65 = aspirin/caffeine/propoxyphene (propoxyphene is an opiate).
Empirin = aspirin/codeine
Lortab ASA (discontinued) = aspirin/hydrocodone
Percodan = aspirin/oxycodone

I’ve never seen any of these prescribed. They are not in my usual pain control algorithm.

[picunurse]

Tylenol over-dose is not just dose dependent. What one has eaten is a factor, as is alcohol or use or other drugs.
When a suspected Tylenol OD is admitted, the drug blood level is checked every 6 hours. If the first level is above (brain fart, #—read high) the patient is started on Mucomyst™treatment.

Acetylcysteine, administered orally, is indicated as an antidote to prevent or lessen hepatic injury which may occur following the ingestion of a potentially hepatotoxic quantity of acetaminophen.
It is essential to initiate treatment as soon as possible after the overdose and, in any case, within 24 hours of ingestion.

If the level hasn’t dropped by 1/2 after 12 hours, the chances of liver failure double.

[BwanaBob]

@edwino

BTW,

Synalgos-DC = aspirin/caffeine/dihydrocodeine

Correction: Synalgos DC is aspirin.caffeine.promethazine (unless they changed the formula).

I had this prescribed when I had my wisdom teeth extracted (and gums cut).
Put me into la-la land.

[Qadgop_the_Mercotan]

@BwanaBob

Correction: Synalgos DC is aspirin.caffeine.promethazine (unless they changed the formula)

Huh??

My online Micromedex still has the ingredients as Aspirin, caffiene, and dihydrocodiene. It’s been that way since the mid-80’s at least.

It’s plain Synalgos that has the ingredients you describe.

[Qadgop_the_Mercotan]

And Synalgos DCA has acetaminophen in place of the aspirin.