# Vicadine+Alcohol=? **URL:** \ **Category:** Factual Questions\ **Created:** [June 29, 2003, 5:38am UTC](https://boards.straightdope.com/t/vicadine-alcohol/185105 "2003-06-29T05:38:06Z")\ **Posts on this page:** 10\ **Page:** 1
**Author:** ![the\_duke\_69](https://avatars.discourse-cdn.com/v4/letter/t/48db29/32.png) [@the\_duke\_69](https://boards.straightdope.com/u/the_duke_69)\ **Post date:** [June 29, 2003, 5:38am UTC](https://boards.straightdope.com/t/vicadine-alcohol/185105/1 "2003-06-29T05:38:06Z")
what would I expect if I mixed the two substances? ---
**Author:** ![Eva\_Luna](https://avatars.discourse-cdn.com/v4/letter/e/e495f1/32.png) [@Eva\_Luna](https://boards.straightdope.com/u/Eva_Luna)\ **Post date:** [June 29, 2003, 5:42am UTC](https://boards.straightdope.com/t/vicadine-alcohol/185105/2 "2003-06-29T05:42:12Z")
REALLY, really bad idea. Depending on quantity, it could kill you. (IANAD, but I’ve been prescribed more than my share of Vicodin, and I take those warnings very seriously.) ---
**Author:** ![the\_duke\_69](https://avatars.discourse-cdn.com/v4/letter/t/48db29/32.png) [@the\_duke\_69](https://boards.straightdope.com/u/the_duke_69)\ **Post date:** [June 29, 2003, 5:44am UTC](https://boards.straightdope.com/t/vicadine-alcohol/185105/3 "2003-06-29T05:44:41Z")
Ok I hade one 350 milligram vicadan and two corronas and one After shock and An Ice 101, as you cant tell I am not completely gone. LOL but I am also using spell correct. just wonder what I could expect. ---
**Author:** ![Panzerfaust](https://avatars.discourse-cdn.com/v4/letter/p/ecc23a/32.png) [@Panzerfaust](https://boards.straightdope.com/u/Panzerfaust)\ **Post date:** [June 29, 2003, 5:50am UTC](https://boards.straightdope.com/t/vicadine-alcohol/185105/4 "2003-06-29T05:50:06Z")
Well, I do it all the time, but I also have a strong natural drug resistance, as well as an even _stronger_ resistance provided by taking huge quantities of drugs on a regular basis, and I also completely lack any sense of self-preservation. Which probably doesn’t answer your question. Expect to be tired. ---
**Author:** ![Zenster](https://avatars.discourse-cdn.com/v4/letter/z/cdc98d/32.png) [@Zenster](https://boards.straightdope.com/u/Zenster)\ **Post date:** [June 29, 2003, 6:06am UTC](https://boards.straightdope.com/t/vicadine-alcohol/185105/5 "2003-06-29T06:06:30Z")
Alcohol affects the chemical transport mechanisms in your liver. Frequently, it accelerates the release rate or time of absorbtion into your bloodstream. A normally benign dose of tranquilizer (barbituate) or painkiller (codeine derivative or analogue) can suddenly be released at a rate that can affect your autonomic functions (i.e., cardiac rythym or respiration). Large doses of these drugs combined with heavy alcohol intake can frequently result in **death**. **I ADVISE YOU TO NEVER REPEAT THIS EXPERIMENT.** When your judgement is sufficiently impaired due to the intense drug synergy that can result from this dangerous combination, it is not unknow to ingest additional quantities that lead to toxic side effects. Many people have died doing this and many more will die in the future. TRY NOT TO BE ONE OF THEM. ---
**Author:** ![Panzerfaust](https://avatars.discourse-cdn.com/v4/letter/p/ecc23a/32.png) [@Panzerfaust](https://boards.straightdope.com/u/Panzerfaust)\ **Post date:** [June 29, 2003, 6:18am UTC](https://boards.straightdope.com/t/vicadine-alcohol/185105/6 "2003-06-29T06:18:06Z")
While I lack the medical background to confirm or deny **Zenster** ’s first point, he’s definitely right on the latter. Keep a sharp eye on that sort of behavior, and avoid it at all costs. I’ve done this before, to the point of pretty severe OD, and I can tell you, it ain’t fun. ---
**Author:** ![mamayama](https://avatars.discourse-cdn.com/v4/letter/m/a6a055/32.png) [@mamayama](https://boards.straightdope.com/u/mamayama)\ **Post date:** [June 29, 2003, 6:34am UTC](https://boards.straightdope.com/t/vicadine-alcohol/185105/7 "2003-06-29T06:34:44Z")
As a pharmacist, I can say: Zenster’s right. This is the sort of combination that can kill, with little warning. When you have a respiratory depressant in your system (Vicodin or other narcotic), it’s no time to be screwing with your liver metabolism. And if you do okay this time, THAT IS ABSOLUTELY NO INDICATION THAT NEXT TIME WILL BE OKAY. Just another form of Russian Roulette. There’s a number of other drugs that, by themselves, are relatively non-toxic, but are potentially lethal with the addition of a little alcohol. ---
**Author:** ![the\_duke\_69](https://avatars.discourse-cdn.com/v4/letter/t/48db29/32.png) [@the\_duke\_69](https://boards.straightdope.com/u/the_duke_69)\ **Post date:** [June 29, 2003, 7:07am UTC](https://boards.straightdope.com/t/vicadine-alcohol/185105/8 "2003-06-29T07:07:18Z")
All I am feeling right now is just a complete numb of nothing. but I am not “gone” I will add another post after I sleep it off. ---
**Author:** ![bibliophage](https://sea3.discourse-cdn.com/straightdope/user_avatar/boards.straightdope.com/bibliophage/32/7615_2.png) [@bibliophage](https://boards.straightdope.com/u/bibliophage)\ **Post date:** [June 29, 2003, 7:14am UTC](https://boards.straightdope.com/t/vicadine-alcohol/185105/9 "2003-06-29T07:14:49Z")
> [@](#): > > \*Originally posted by the\_duke\_69 \* > \*\*Ok I hade one 350 milligram vicadan and two corronas and one After shock and An Ice 101, as you cant tell I am not completely gone. \*\* The abuse of controlled substances is illegal. I direct your attention to the ATMB thread [FAQ - guidelines for posting at the SDMB](http://boards.straightdope.com/sdmb/showthread.php?s=&threadid=106617) > [@](#): > > Limited discussion of past use of drugs is OK, discussion of current use is not. Please include a disclaimer that the drug is illegal in the US. Since the question has been answered (by a pharmacist no less), I’ll close this thread. bibliophage moderator GQ [mod hat off] > [@](#): > > LOL but I am also using spell correct. Might want to get your money back. ---
**Author:** ![Zenster](https://avatars.discourse-cdn.com/v4/letter/z/cdc98d/32.png) [@Zenster](https://boards.straightdope.com/u/Zenster)\ **Post date:** [June 29, 2003, 7:24am UTC](https://boards.straightdope.com/t/vicadine-alcohol/185105/10 "2003-06-29T07:24:39Z")
Thanks for checking in, **duke**. Get some rest and plenty of (non-alcoholic) liquids.