What is an Allergen?

In any case, I think the underlying statement (the one I originally challenged, quoted below) is false, on two levels.

  1. It appears there are mechanisms by which exposure to smoke or other non-protein-based substances can result in an allergic outbreak.

  2. (Off topic for this thread, but not the hijack to the other one) Regardless of the precise mechanism, or even the precise type of reaction, responding to the question “may I expose you to chemical X?” with “Please don’t - I’m allergic” is still a sensible and reasonable response.
    The waiter does not need to understand or care that your aversity to shellfish is actually because of an intolerance. The person offering you a glass of sulphited wine does not need to know or care that the sulphite releases Sulphur Dioxide, which is then a factor in a chain of events, leading to anaphylaxis. “No thanks - I’m allergic to it” is probably the right thing to say.